In the last decade, if not only in the last five years, an unprecedented advance occured in the understanding of the primary defect involved in Duchenne muscular dystrophy. As a consequence, new promising lines and trends of research emerged: molecular diagnosis by use of anti-dystrophin antibodies or by DNA probes and those more strictly dealing with the perspectives of therapy, including myoblast transfer and gene therapy. The many outstanding papers which appear in this volume document the incredible power of modern tools of medical research in unravelling the complexity of the pathology and in finding new therapeutical strategies.
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