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My Beautiful Genome: Exposing Our Genetic Future, One Quirk at a Time [Paperback]

Lone Frank
4.3 out of 5 stars  See all reviews (7 customer reviews)


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Book Description

October 3, 2011 1851688331 978-1851688333
What if you could predict your future – which political party you will vote for, what kind of person you will marry, which disease will end your life, whether your blue mood will fester into something more troubling, even debilitating. Would you want to know? Taking a uniquely intimate and cheeky approach to the personal genomics revolution, internationally acclaimed science writer Lone Frank swabs up her genetic code to explore who any of us are in the days when a catalogue of your full six billion DNA building blocks is available for $10,000 and the local Walgreens offers genetic screening tests to anyone. She challenges the august Nobel Prize winners and the hyperactive business mavericks who are pushing to map and decipher every fetus’s genome within the next decade. She tests the potential to detect diseases early, as well as our capacity to develop chronic anxieties when our DNA is seen as a death sentence. She ponders whether personality, including her own above-average irritability and non-conformity, can really be reduced to biochemistry. And she prods the psychologists who hope to uncover just how much or how little our environment will matter in the new genetic century – a quest made all the more gripping as Frank considers her family’s and her own struggles with depression. At turns compellingly candid and irreverently insightful, Frank provides the first truly personal account of the new science of consumer-led genomics – and to what extent our genes determine our destiny. Lone Frank is the author of The Neurotourist: Postcards from the Edge of Brain Science (ISBN 9781851687961). She holds a PhD in neurobiology and was previously a research scientist working in the biotechnology industry in the United States. An award-winning science journalist and TV documentary presenter, she has written for such publicationsn as Scientific American, Science, and Nature Biotechnology and is a frequent speaker at venues including Harvard Medical School, the Library of Congress, the Royal Society, and TED. Praise for The Neurotourist “A fascinating exploration of the most intriguing brain experiments so far.” New Scientist “Riveting.” Rita Carter, author of Mapping the Mind


Editorial Reviews

Review

Review Source: Publishers Weekly

Review Date: 6 June 2011

Review Content:A probing biological memoir... Refreshing [and] wonderfully poetic.

About the Author

Lone Frank is the author of The Neurotourist: Postcards from the Edge of Brain Science (ISBN 9781851687961). She holds a PhD in neurobiology and was previously a research scientist in the biotechnology industry. An award-winning science journalist and Danish TV presenter, she has written for such publications as Scientific American, Science, and Nature Biotechnology.

Product Details

  • Paperback: 328 pages
  • Publisher: Oneworld Publications (October 3, 2011)
  • Language: English
  • ISBN-10: 1851688331
  • ISBN-13: 978-1851688333
  • Product Dimensions: 5.3 x 1 x 8.5 inches
  • Shipping Weight: 9.6 ounces
  • Average Customer Review: 4.3 out of 5 stars  See all reviews (7 customer reviews)
  • Amazon Best Sellers Rank: #799,462 in Books (See Top 100 in Books)

More About the Author

Lone Frank has a shady past as a research scientist with a Ph.D in neurobiology. However, a decade ago she decided to leave the lab bench to become a full-time science writer. Today she is Denmark's most distinguished science writer and a well-known voice in debates about science, technology and society. She writes for the pre-eminent Danish newspaper, Weekendavisen, as well as for publications outside her native country such as Science, Nature and Frankfurter Allgemeine Zeitung. She has co-produced and presented several series of science programs on cutting edge science for the Danish National Broadcasting Corporation. Currently, she is making a documentary on the science of happiness and writing her next book.

Lone Frank has appeared on NPR's Leonard Lopate Show and Radio Lab as wells as Wisconsin Public Radio's To the Best of our Knowledge.

Customer Reviews

4.3 out of 5 stars
(7)
4.3 out of 5 stars
Most Helpful Customer Reviews
3 of 3 people found the following review helpful
5.0 out of 5 stars Hang onto your codons and enjoy the ride January 19, 2012
Format:Paperback
Armed with dry wit and an art for self depreciative analysis, Dr Frank embarks on a journey through the recent developments in human genetics. She fronts pioneers and personalities of genetic science, past and present, and cuts straight to the big issues in their field. These meetings, conducted through various media and in person, are always reported insightfully, usually humorously. She treats herself as the guinea pig, using different commercial and research assay and analysis techniques to test her current genetic wellbeing and future health, both physical and mental, and that of others including her putative progeny. As a starting point, she needs to honestly appraise herself, her dead parents and surviving relatives in order to focus her research.

As an example, Frank's meeting with psychiatric epidemiologist, Kenneth Kendler, is warmly described and none of the ambiguity of genetic and psychiatric research or their applications is avoided. But her reaction after the meeting, when events contrive to confront the impact of her genetic makeup on her life to date, is numbing. Frank acknowledges that many genetic insights are intuitive anyway, and may not require brain scans to discover, but she has the scans anyway. This thoroughness is the strength of the book. And it is only through this approach that Frank is equipped to comment on "the war between epidemiologists and genetic researchers", between individual processes and statistics. This approach, based on the assertion that there are ultimately no healthy or unhealthy genes, only evolutionary variation, enables Frank to tackle daunting topics such as the inheritability of schizophrenia and autism spectra phenomena objectively. These examples are all selected from one of the book's eight rich chapters.
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3 of 3 people found the following review helpful
4.0 out of 5 stars for anyone wondering what "personal genomics" means September 13, 2011
By Chris
Format:Paperback
Personal genomics is not coming, it's here. But it's not so common that we can all get our DNA sequenced and analyzed and interpreted tomorrow. Lone Frank gives us a preview of the tests we'll all be having soon, and the questions those tests will raise about our health, identity, and history. The science is explained through personal stories and entertaining encounters with the researchers who are at the cutting edge of human genomics and its many implications.
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2 of 2 people found the following review helpful
Format:Paperback
A great story of how you can gain a completely new perspective of yourself based on knowledge of your code - I can highly recommend it

Great review in Financial Times
[...]

Science writer Lone Frank gets up close and personal with her genetic code
A decade or so after scientists triumphantly revealed a first draft of the human genome, the 3bn biochemical letters that make up our DNA, the script is turning out to be far harder to decipher - and therefore to use - than the enthusiasts led us to believe.
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1 of 1 people found the following review helpful
5.0 out of 5 stars Informative and Enjoyable March 3, 2012
By Jetgirl
Format:Paperback
I found this book a fascinating and very easy read on a subject I know very little on. As a health professional i have a basic understanding of molecular genetics, but this book really opened my eyes up in to the commercial application of genetics and the link between genes and who we are, as well as the big knowledge gaps that are yet to be filled. I walked away feeling that it may be fun to get my genetic fortune-telling done. Frank narrates a scientific and sociological topic from her own experiments in getting her genome read and interviewing other people, in such a way that you can snuggle up on the couch with the book and feel like you are reading a fun novel.

Summary:

The first part of this book explores popular genetics-with genealogy now the most popular hobby in the USA, a market has grown for people tracing their heritage through genetic sequences. Commercial organisations have also grown where people pay to for a genome sequence to get risk factors for certain diseases and certain traits. However, how valid are these commercial products? There are problems with determining risk factors for diseases, as association studies these genetic markers are based on can be weak and don't account for the multifactorial nature of disease, familial markers are left out, a lot of diseases may be hereditary but the genetic marker hasn't yet been identified, and we are forever finding new disease markers that substantially change ones genetic risk. Genetic genealogy is also questionable. It looks at only the halotypes of one in a thousand distance ancestors, as mitochondrial DNA and the Y chromosome are the only parts of DNA that don't undergo recombination.
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3.0 out of 5 stars Enjoyable though imperfect. (Avoid on Kindle) April 26, 2013
By DD
Format:Kindle Edition|Amazon Verified Purchase
An enjoyable story of a women exploring her own genome. The book skillfully gets across the importance of this new field. However, it does suffer from a few clumsy phrases. Additionally the kindle edition is filled with typos.
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4.0 out of 5 stars My beautiful genome December 26, 2012
Format:Paperback|Amazon Verified Purchase
Very interesting book with bravely revealing personal experience of the author.
I found posible answers at some my questions, considering the role of gene in the case of depression.
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4.0 out of 5 stars A very informative and entertaining book indeed! September 18, 2011
By Kurt
Format:Paperback
A very informative and entertaining book for all of us interrested in genetics from a layman perspective. Here, the complicated subjects are finally explained in a understandable way for us "Dummies". Lone Frank invests her own body in a quest for knowledge of her DNA and what this knowledge can be used for today and in the future. She talks to world leading scientists and share her own thoughts with a lot of wit.
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