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Mysterious Epigenome, The [Kindle Edition]

Thomas E. Woodward , James P. Gills
4.2 out of 5 stars  See all reviews (30 customer reviews)

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Book Description

In this creative and inventive book, authors Thomas E. Woodward and James P. Gills take readers on an exploration of the human epigenome. Acting as tour guides leading visitors through a 3-D model of a human cell, Woodward and Gills bring to life the human molecular makeup. Readers (as visitors) will get up close and personal with the minute details of human molecular structure, including E. coli, flagellum, a DNA helix, an RNA molecule, and more. By seeing it with their own eyes, readers will gain a better understanding of their genetic systems and a better appreciation for the Creator who put this all into place.

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Editorial Reviews

About the Author

Thomas E. Woodward (PhD, University of South Florida) is a professor at Trinity College of Florida. He is founder and director of the C.S. Lewis Society, and lectures in universities on scientific, apologetic, and religious topics. The author of Doubts About Darwin, he has been published in Moody magazine and Christianity Today.

James P. Gills, MD has earned a reputation as the most experienced cataract surgeon in the world. He is the founder and medical director of the renowned St. Luke’s Cataract & Laser Institute in Tarpon Springs, Florida, and has dedicated his life to restoring much more than physical vision. His not-for-profit publishing outreach, Love Press, has distributed well over three million copies of his books on a donation basis through LoveLines: The Honor Innovation.

Product Details

  • File Size: 2530 KB
  • Print Length: 170 pages
  • Page Numbers Source ISBN: 0825441927
  • Publisher: Kregel Publications (March 30, 2012)
  • Sold by: Amazon Digital Services, Inc.
  • Language: English
  • ASIN: B007Q3LW0G
  • Text-to-Speech: Enabled
  • X-Ray:
  • Lending: Not Enabled
  • Amazon Best Sellers Rank: #169,401 Paid in Kindle Store (See Top 100 Paid in Kindle Store)
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Customer Reviews

Most Helpful Customer Reviews
35 of 41 people found the following review helpful
4.0 out of 5 stars Darwin knew nothing of the complex cell February 8, 2012
By Joan N.
The Human Genome Project was a great success in advancing our knowledge of DNA, but nearly a decade later, the scientists are finding out there is much more to the story.

Scientists are now finding a complex system instructing DNA called the epigenome. (from the Greek, epi, having the nuance of "over" or "above.") "The epigenome refers to the entire coordinated system of 'control information' that resides above and beyond the bare DNA sequences." (54) The authors liken the epigenome to the director of the DNA orchestra.
The authors focus on two areas: the latest news from the world of DNA, and how science stumbled upon the control system of our DNA. The theme of human health is emphasized throughout the book.

The authors reveal the complexity of the cell. Human DNA has 3.1 billion letter-pairs, the equivalent of 14,000 books of 250 pages each. Some plants have even more, such as the Paris japonica, having the record at 149 billion letters per cell. Even a species of wheat has five times as much DNA as the human cell. But the biggest surprise? The record is held by a single-cell species, Polychaos dubium, with about 670 billion letters of DNA. And Darwin knew nothing of it.

What is the role of the eipgenome system? Its central function is to control the expression of DNA. But the picture is not complete. Research on the epigenome is accelerating, and scientists around the world are delving into both the molecular structure and the functional roles of the epigenome's sections and layers." (69)

One ongoing mystery has been how a stem cell, specifically, a fertilized human egg cell, can differentiate into all the types of tissues in the body. The epigenome has been shown to be the key.
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33 of 42 people found the following review helpful
5.0 out of 5 stars Darwin, move over, and let epigenetics take over! January 31, 2012
An overemphasis on natural history, especially evolutionism, currently exists at all levels of education. This has left most people in the dark regarding the real scientific advances taking place right now that are helping us unlock the mysteries of life and health. If you have recently taken a general biology course, read this book and I can guarantee you will learn something new. And if it doesn't upset you that this information wasn't in your biology course, it should!

Woodward and Gills do a fantastic job of introducing the topic of epigenetics in a creative, lucid, and thoughtful way that anyone can understand. As the authors state on p. 14, "our DNA responds to cues from a higher control system written into the cell, and the programming of this system can even change over time." Epigenetics is the "higher control system", and we have just scratched the surface on our knowledge of what it is and what it does.

Genetic mutations are the supposed "engines that drive evolution." However, when it comes to epigenetics, these so-called engines appear to be off, as phenotypic changes are passed from parent to offspring with no sign of a genetic change having occurred. More than ever, our understanding of the genome and epigenome makes it clear that we were indeed fearfully and wonderfully made. It is past time for Darwinism to move to the back of the class, or to another class like history or philosophy, so we can make more room in science courses to talk about real scientific advances. If you are not convinced that a paradigm shift in biology education is necessary and long overdue, then you haven't read The Mysterious Epigenome!
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2 of 2 people found the following review helpful
3.0 out of 5 stars Just okay July 4, 2013
Woodward and Gills's book "The Mysterious Genome" (***) provides overviews of some of the latest in research on epigenetics in an easy-to-read format. The highlight for me was the information itself: summaries of epigenetic information in the form of methylation, histones, membranes, cell architecture, 3D shape of DNA, and their influence on development. It also touches on the health and diet-related significance of epigenetics (a subject covered very well in Cate Shanahan's great book Deep Nutrition: Why Your Genes Need Traditional Food). It's a good summary in that regard (although you can get equal or better detail in either of Stephen Meyer's books, or Jablonka's Evolution in Four Dimensions). However, I have a few problems with the book. First of all, I found the fictionalized journeys through the cell pretty cheesy. If you don't have a good idea of the basics of genetics (DNA, RNA, proteins), the format probably works, but if you do, those introductory sections are pretty simple and somewhat boring. (Thankfully, the book itself is short enough to read in a sitting or two.) Also, while the authors support intelligent design (a theory I too support), portions of the book come from a strong Christian perspective. I don't really have a problem with that either, but I can't support their particular stance on theology (i.e., supernaturalism). David Ray Griffin provides a much better discussion of the relation of God and religion in general in relation to science, particularly in his book ... Read more ›
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Most Recent Customer Reviews
5.0 out of 5 stars Who knew?
I love science and new technology and this fits the bill. Easy to read and understand and gives one hope and courage for the future.
Published 1 month ago by Phyllis F Elmore
3.0 out of 5 stars A lot of story telling if you are into that.
I was hoping for more science on how the epigenome has developed and reacts in today's world. At the end of the day this is a creator vs. Read more
Published 1 month ago by Well Doc
4.0 out of 5 stars More focus on epigenetics and less on their fantasyland ride.
I would have liked Woodward and Gills to explain epigenetics more and left out their narration and less about rides in the tommorwland-style tour down to the molecular level of a... Read more
Published 3 months ago by Jon Covey
4.0 out of 5 stars PARADIGM CHANGING SUBJECT ...
Einstein once said: "Religion without science is blind, but science without religion is lame." This book clearly demonstrates Einstein's wisdom in both regards. Read more
Published 8 months ago by Robert Steven Thomas
1.0 out of 5 stars Not what I was expecting
I was expecting a novel that looked at the beauty and complexity of the inner workings of the cell. Instead of allowing the reader to be amazed at the interactions of genome with... Read more
Published 9 months ago by Jan St.Pierre
5.0 out of 5 stars Tons of New Information!
Many new developments in the world of epigenetics are very well treated in this compact volume! Very well written and comprehensive in scope.
Published 11 months ago by Baron of Locksley
5.0 out of 5 stars It's worth a read
For those new to epigenetics, this book will have you understanding many of the concepts in this thrilling new field. Read more
Published 11 months ago by Larry Turner
5.0 out of 5 stars Evolution is a Lie
Want to know why then read this work and you will understand and you be angry about the lies you have been taught in the government and private secular institutions that you... Read more
Published 11 months ago by Noah
5.0 out of 5 stars Complex subject written for a layman
I'm not a scientist so I doubt it is fair or right for me to critique the books scientific claims. What I can say is that the author did a good job of explaining complex ideas in... Read more
Published 12 months ago by Steve Hanchett
5.0 out of 5 stars Wonderful informative book
This author wrote this book to the normal person and is able to lead you through a very complex subject with ease. This mystery is quite fascinating and thouroughly!
Published 13 months ago by talk2katheryn
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