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NMR in Drug Design (Analytical Biotechnology)
 
 
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NMR in Drug Design (Analytical Biotechnology) [Hardcover]

David J Craik (Editor)

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Book Description

0849378249 978-0849378249 February 1, 1996 1
NMR in Drug Design discusses the use of nuclear magnetic resonance (NMR) in studies of the design, structure, mechanism, and actions of pharmaceutical agents. Topics include rational drug design, NMR techniques in drug design, conformational analysis by NMR, macromolecular structure determination, protein-ligand interactions, drug-DNA interactions, and studies of enzyme mechanisms by NMR. This reference book provides invaluable practical information to the scientist working in drug design or NMR research.

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Inside This Book (learn more)
First Sentence:
New drug development is based on two complementary strategies. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
quinomycin antibiotics, piperizine ring, deoxyribose spin systems, echinomycin complexes, free trimethoprim, major groove protons, piperizine moiety, terephthalamide derivatives, nogalose sugar, protease backbone, pyrimethamine analogues, random fractional deuteration, hexamer duplex, shielding parameter, isotope filters, pterin ring, overall correlation time, minor groove binders, trial distances, potential hydrogen bond donors, intercalation site, drug signals, molecular correlation time, peptide plane, ligand resonances
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Oxford University Press, Methods Enzymol, Nucleic Acids Res, Academic Press, John Wiley, Anti-Cancer Drug Design, Clarendon Press, Function Genet, Peptide Protein Res, Proteins Struct, American Chemical Society, Practical Approach, The Nuclear Overbauser Effect, Cambridge University Press, Macmillan Press, Marcel Dekker, Nature Struct, Perkin Trans, Aided Mol, Cancer Res, Liebigs Ann, Pergamon Press, Plenum Press, Principles of Medicinal Chemistry
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