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NMR Spectroscopy Explained: Simplified Theory, Applications and Examples for Organic Chemistry and Structural Biology [Hardcover]

Neil E. Jacobsen
5.0 out of 5 stars  See all reviews (5 customer reviews)

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Book Description

August 24, 2007 0471730963 978-0471730965 1
NMR Spectroscopy Explained : Simplified Theory, Applications and Examples for Organic Chemistry and Structural Biology provides a fresh, practical guide to NMR for both students and practitioners, in a clearly written and non-mathematical format. It gives the reader an intermediate level theoretical basis for understanding laboratory applications, developing concepts gradually within the context of examples and useful experiments.
  • Introduces students to modern NMR as applied to analysis of organic compounds.
  • Presents material in a clear, conversational style that is appealing to students.
  • Contains comprehensive coverage of how NMR experiments actually work.
  • Combines basic ideas with practical implementation of the spectrometer.
  • Provides an intermediate level theoretical basis for understanding laboratory experiments.
  • Develops concepts gradually within the context of examples and useful experiments.
  • Introduces the product operator formalism after introducing the simpler (but limited) vector model.

Frequently Bought Together

NMR Spectroscopy Explained: Simplified Theory, Applications and Examples for Organic Chemistry and Structural Biology + Understanding NMR Spectroscopy, Second Edition + Structure Determination of Organic Compounds: Tables of Spectral Data
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Editorial Reviews


"The uses of the many modern multiple NMW techniques are explained and demonstrated quite well." (CHOICE, September 2008)

From the Back Cover


Used in concert with complementary analytical techniques such as light spectroscopy and mass spectrometry, Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool for the determination of organic structure. This book fosters a real-world understanding of NMR spectroscopy and how it works without burying the reader in technical details and physical and mathematical formalism. With an accessible, clear style and approach, NMR Spectroscopy Explained:

  • Introduces readers to modern NMR spectroscopy as it is applied to the analysis of organic compounds and biomolecules

  • Minimizes complicated theory and focuses on the practical aspects of NMR spectroscopy

  • Provides comprehensive coverage of how NMR spectroscopy experiments actually work and how to optimize them on the spectrometer

  • Provides examples of every experiment, with detailed interpretation of data

  • Presents essential descriptive theory in mainly nonmathematical terms

The guide starts with a basic model and expands it one step at a time, complete with experiments and examples, helping readers who are not experts in physics or physical chemistry to develop an empowering understanding of even the most complex biological NMR spectroscopy techniques. It is an ideal reference for professionals in industry and academia who use NMR spectroscopy technology, NMR facility managers, and upper-level undergraduates and graduate students in organic chemistry, biochemistry, pharmacology, biophysics, and engineering.

Product Details

  • Hardcover: 688 pages
  • Publisher: Wiley-Interscience; 1 edition (August 24, 2007)
  • Language: English
  • ISBN-10: 0471730963
  • ISBN-13: 978-0471730965
  • Product Dimensions: 9.8 x 7.5 x 1.6 inches
  • Shipping Weight: 2.8 pounds (View shipping rates and policies)
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (5 customer reviews)
  • Amazon Best Sellers Rank: #943,125 in Books (See Top 100 in Books)

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Most Helpful Customer Reviews
8 of 8 people found the following review helpful
5.0 out of 5 stars Great NMR Book November 5, 2009
Format:Hardcover|Verified Purchase
I've been working with NMR for over 11 years and over the years have acquired numerous books on the subject. This book is hands down the best on the subject. The author clearly explains everything, where other books throw up a graph/spectrum/equation and expect you to figure it out magically at times. Areas I've been confused on for years suddenly all make sense.

This book along with "Structure Determination of Organic Compounds" by Pretsch, Buhlmann, and Affolter and maybe "200 and More NMR experiments" by Berger and Braun are currently the only NMR books worth owning. Skip the rest.

Two thumbs way up!!
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12 of 14 people found the following review helpful
5.0 out of 5 stars Buy this book if you really want to understand nmr December 2, 2007
Format:Hardcover|Verified Purchase
Initially I wanted to write a review for this book after I finish the whole book. However, since the publication of this book, I have noticed that nobody has ever written a review. I have only finished approximately 400 pages but I want to let people to know that this is clearest exposition on modern nmr spectroscopy I have ever come across. I have read a number of nmr books. These include the following

J.D. Roberts "ABC of FT NMR"
T. Claridge "High Resolution NMR spectroscopy in organic chemistry"
J. Sanders " Modern NMR spectroscopy"
H. Friebolin "Basic One- and Two-Dimenionsal NMR"

None of the above is as good as this book. The one that comes close to this is Friebolin's book. However, it is not as detail and does not cover topics such as operator formalism and density matrix. This book also covers the basic theoretical principles and presented in a very lucid way. I enjoy reading this book tremendously.

Dec 14, 2009. It has been almost 2 years since I wrote the initial review. Since then, I have the opportunity to read the whole book a second time. My opinion of this book remains the same. If you really want to understand NMR, you cannot go wrong with this book.
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3 of 3 people found the following review helpful
5.0 out of 5 stars Great Book, Great Professor May 9, 2010
Format:Hardcover|Verified Purchase
I've always found NMR to be extremely difficult but when I got this book, it really helped me to understand how to read and analyze NMR spectra. I also had the great honor of having the author of this book as my professor recently and the guy really knows his stuff and is great at conveying his knowledge. So if you never understood NMR or don't really understand it that much, or just want a great book about NMR, this is the book for you and you can trust in the fact that the author knows his stuff. I know this book is costly, but trust me you won't regret it at all!
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1 of 1 people found the following review helpful
5.0 out of 5 stars excellent introduction to nmr theory February 5, 2013
I have read several books about NMR theory and practice, and this book provides by far the most lucid description of essentially all aspects of modern NMR (polarization transfer, coherence selection, cross-relaxation, exchange phenomena, solvent suppression, pulsed field gradients, triple resonance methods, residual dipolar couplings, etcetera). The book begins with a simple vector model, progresses to a product operator description, and toward the end, introduces readers to the density matrix representation. In addition to providing a strong conceptual understanding of pulse sequences and sequence modules (e.g., INEPT, DPFGSE, COSY, NOESY, ROESY, TOCSY, HSQC, HMQC, HMBC), the book also describes practical considerations like hardware, data collection, and data processing. The final chapter of the book describes the application of NMR to structural biology. This chapter might have benefited from a description of modern approaches for probing the dynamics of biological systems (e.g., relaxation dispersion NMR), which are one of the primary strengths of NMR compared to diffraction or microscopy for studies of biological systems. I recommend this book for any NMR user that seeks a greater conceptual understanding of the behavior and manipulation of nuclear spin states (i.e., how their NMR experiments work at the level of the ensemble of nuclear spins), and as a foundation for reading more advanced texts like those by Slichter, Abragam, Ernst, or Levitt.
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5.0 out of 5 stars Perfect :) May 5, 2013
Format:Hardcover|Verified Purchase
This book include not only principle but also practical things. Most interesting point is this book include the feelings of the author. E.g. Why we choose vector model or product operator. This book supports the conflict of our mind why we choose the reasonable strategy to illustrate the NMR.
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