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NMR Spectroscopy of Glycoconjugates
 
 
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NMR Spectroscopy of Glycoconjugates [Hardcover]

Jes?s Jim?nez-Barbero (Editor), Thomas Peters (Editor)


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Book Description

3527304142 978-3527304141 December 30, 2002 1
While for many years NMR spectroscopy was one of the most useful methods of analyzing smaller molecules, nowadays it is an indispensable tool in determining the structure of complex biomolecules too. One reason for this is not least the development of increasingly powerful appliances that enabled this complicated analysis using tiny amounts of the substances in the first place. Just as the image of a 2D spectrum allows an insight into the spatial structure of a molecule, the chronological examination of an NMR experiment enables the description of the molecular dynamics. It is only by explaining such characteristics that we can really come to understand the functioning of biomolecules.
This book is neither a purely analytical nor bioorganic work, and as such fills a gap for everybody working in determining the structure of carbohydrates and their conjugates. In a clearly comprehensible manner, the text summarizes the latest knowledge surrounding the use of NMR spectroscopy with such biologically important substance classes as polysaccharides, glycoproteins and glycolipides. Furthermore, it provides an insight into the interactions with other biomolecules such as proteins, nucleic acids or carbohydrates. A valuable guide for all glucochemists.

Editorial Reviews

From the Back Cover

While for many years NMR Spectroscopy was one of the most useful methods of analyzing smaller molecules, nowadays it is an indispensable tool in determining the structure of complex biomolecules too. One reason for this is not least the development of increasingly powerful appliances that enabled this complicated analysis using tiny amounts of the substances in the first place. Just as the image of a 2D spectrum allows an insight into the spatial structure of a molecule, the chronological examination of an NMR experiment enables the description of the molecular dynamics. It is only by explaining such characteristics that we can really come to understand the functioning of biomolecules.
This book is neither a purely analytical nor bioorganic work, and as such fills a gap for everybody working in determining the structure of carbohydrates and their conjugates. In a clearly comprehensible manner, the text summarizes the latest knowledge surrounding the use of NMR spectroscopy with such biologically important substance classes as polysaccharides, glycoproteins and glycolipides. Furthermore, it provides an insight into the interactions with other biomolecules such as proteins, nucleic acids or carbohydrates. A valuable guide for all glucochemists.

Product Details

  • Hardcover: 336 pages
  • Publisher: Wiley-VCH; 1 edition (December 30, 2002)
  • Language: English
  • ISBN-10: 3527304142
  • ISBN-13: 978-3527304141
  • Product Dimensions: 9.4 x 6.8 x 0.9 inches
  • Shipping Weight: 1.7 pounds
  • Amazon Best Sellers Rank: #5,017,772 in Books (See Top 100 in Books)

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Inside This Book (learn more)
First Sentence:
NMR spectroscopy is undoubtedly a technique of the utmost importance in studies on the structure, dynamics and function of many kinds of molecules, including those pertaining to the fields of carbohydrate chemistry and biochemistry. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
similar torsional angles, full relaxation matrix approach, ulosyl bromide, dipolar data, sulfated saccharides, residual dipolar coupling constants, refocusing interval, biomolecular force fields, thioglycosidic linkage, residual dipolar couplings, dipolar coupling data, relaxation vectors, heparin disaccharide, anomeric resonances, alignment tensor, negative cross peaks, overall correlation time, chemical shift variations, simulated annealing protocol, minimum image convention, glycolipid structure, protein protons, motional parameters, glycosidic torsion angles, rigid fragment
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Magn Reson, Chem Soc, Carbohydr Res, New York, Simulation Methods, Monte Carlo, Homonuclear Selective Methods, Example Application, Perkin Trans, John Wiley, Pure Appl, Tetrahedron Lett, Acad Sci, Academic Press, Adv Carbohydr, Blackwell Science, Study Carbohydrate-Protein Interactions, Biol Chem, Client Soc, Covalent Tethering of Lex Units, Elsevier Science, Experimental Aspects, Nature Struct, Reson Chem
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