on September 9, 2010
I am a dentist and began taking D-3 after testing deficient. I soon noticed that my gums stopped bleeding when flossing and so I now provide a Calcium/D-3 combination to my patients; then I noticed my high blood pressure dropped and I actually passed out from low blood pressure! I was taking two blood pressure medications and have cut back to one. I dropped 10 pounds in two months and have now dropped another 5 pounds. Every time I notice a beneficial change in my body, I go online and find that, yes, D-3 can cause that. My wife's leg pains are caused by D-3 deficiency according to her cardiologist. It is recognized as a prevention measure for several cancers. I took 10,000 each day until my level hit 70, then cut back to 5,000. I could also say that my mental health has improved tremendously. All of the good things you associate with being out in the sun happen when you take D-3.
on November 8, 2009
I am so glad to find this strength available on Amazon so affordable. These little tiny perles are so easy to take it's a pleasure. My doctor told me that for high immunity he would recommend maintaining a blood level of 75-80 ng/mL. After a month on 5000 a day (one perle) he checked my level and it was only 35. He's having me take 2 a day, 10,000 units, for 3 months and will check again. The correct test is called "25 Hydroxyvitamin D".
There's a lot of interesting information on this topic at[...], and they sell a home test.
on October 5, 2010
As a hospital pharmacist and editor for a newsletter for hospitals around the country, I am well aware of the activity of vitamin D-3 (cholecalciferol). It's more potent then vitamin D-2 (ergocalciferol) and I personally like the gel caps. Vitamin D affects about 200 genes in the body and there are vitamin D receptors located in the heart. They're not there for nothing. High-dose vitamin D therapy can be used for a number of conditions that are too numerous to mention. 5,000 units/day taken by the average weight perons should result in a serum level of about 40-45ng/ml 25-hydroxy-D. Higher doses may be needed for some individuals to bring them into the 50-60ng/ml range. See http:[...] for more information.
on January 27, 2010
After out naturepath suggested this product, our entire family is taking one a day. Our previously trashed immune systems have finally gotten the break they deserve. We have all been sooo healthy; without colds, or flu, or anything else. It has been the single most beneficial supplement we have ever taken. Our family loves it.
on April 30, 2012
New test results came in for the Vitamin D3 25-hydroxy levels. I was taking 40,000 IU of another brand in order to get my level to the optimal level (around 85 ng/mL), but even at 40,000 IU I was still too low (43 ng/mL). But with this brand of D3, I only have to take 15,000 IU to get to the optimal level.
I did all of this under doctor supervision. My doctor also highly recommend to take Vit K with the Vit D3 pills. Hypercalcemia (calcium toxicity) has been shown to arise from Vit K deficiency, and Vit D3 causes your body to metabolise Vit K like crazy. So unless you want hardened arteries and a bunch of other possibly deadly side-effects, you need to take Vit K! Better yet, go see a doctor that knows about the recent studies (published around 2010, 2 years ago) on Vitamins D3 and K, and get your levels up with medical supervision, like I did.
REASON FOR MY SUPPLEMENTATION:
I developed late onset asthma, mainly during exercise and during seasonal allergies. I went to several specialists to see if this could be corrected. All I got were inhalers from these doctors. Then, I found a sports medicine doctor that was also into health and rejuvenation. He has been a God-send. He has helped me discover that Casein protein found in milk products (and some body-building supplements) and my low D3 levels were to blame. I no longer have asthma attacks, and haven't been sick in over a year - even when my kids and wife were sick.
To be fair, Casein was the real culprit to the asthma and seasonal allergy issues, but the benefits of Vit D3 cannot be ignored. I have found that my knees don't hurt anymore (which is damage from my years in the Army), I sleep better at night, and I have a more positive outlook. One only has to search on PUBMED (an online library of scientific experiments) to see what the amazing benefits of vitamin D3 (and K) can do.
Best of luck!
on November 21, 2012
itamin D3 deficiency is common in older adults and has been implicated in psychiatric and neurologic disorders. For example, in one study of 80 older adults (40 with mild Alzheimer’s disease and 40 nondemented persons), Vitamin D3 deficiency was associated with low mood and with impairment on two of four measures of cognitive performance.6
Musculoskeletal disorders have been linked to Vitamin D3 deficiency in a number of studies. One of the newest studies explored the role that low Vitamin D3 levels play in the development of chronic low back pain in women. Sixty female patients in Egypt complaining of low back pain lasting more than three months were studied. Researchers measured levels of Vitamin D3 in the women with low back pain and compared those levels to those of 20 matched healthy controls.
The study revealed that patients with low back pain had significantly lower Vitamin D3 levels than controls. Low Vitamin D3 levels (25 OHD < 40 ng/ml) were found in 49/60 patients (81 percent) and 12/20 (60 percent) of controls.7
One of the best known and long-established benefits of Vitamin D3 is its ability to improve bone health and the health of the musculoskeletal system. It is well documented that Vitamin D3 deficiency causes osteopenia, precipitates and exacerbates osteoporosis, causes a painful bone disease known as osteomalacia, and exacerbates muscle weakness, which increases the risk of falls and fractures. Vitamin D3 insufficiency may alter the regulatory mechanisms of parathyroid hormone (PTH) and cause a secondary hyperparathyroidism that increases the risk of osteoporosis and fractures.8
Scientists are developing a greater appreciation for Vitamin D3’s ability to improve cognition. In a recent study, Vitamin D3 deficient subjects scored worse on mental function tests compared to individuals who had higher levels of the Vitamin.9 The researchers wrote, “In conclusion, the positive, significant correlation between serum 25(OH)D concentration and MMSE [mental state examination scores] in these patients suggests a potential role for Vitamin D in cognitive function of older adults.”
Scientists have linked various aspects of immune health to a Vitamin D3 deficiency. Vitamin D3 regulates T cells, which are important to the functioning of a strong immune system. Vitamin D3 acts as an immune system modulator, preventing excessive expression of inflammatory cytokines and increasing the killing efficiency of macrophages. In addition, it dramatically stimulates the expression of potent anti-microbial peptides, which exist in immune system cells such as neutrophils, monocytes, natural killer cells, and in cells lining the respiratory tract. These Vitamin-D3-stimulated peptides play a major role in protecting the lung from infection.13
In addition, Vitamin D3 deficiency may influence development and progression of various autoimmune diseases.14
Vitamin D3 deficiency has been linked to a host of other conditions such as high blood pressure, fibromyalgia, diabetes, multiple sclerosis, rheumatoid arthritis, and an increased risk of pre-eclampsia and insulin resistance during pregnancy.11,15-16 Most recently, low Vitamin D3 levels have been linked to an increased prevalence of early age-related macular degeneration.17
In many of my patients, even after consuming 2,000 to 4,000 IU of Vitamin D3 per day, their test results indicate that their Vitamin D3 levels have not increased. These patients needed to consume 8,000 IU of Vitamin D3 per day to achieve proper blood levels of the Vitamin. Patients should, therefore, have their physicians test their serum 1,25-dihyroxy D3 levels to determine the proper level of supplementation required. Testing is very important due to the fact that, in a small number of patients, Vitamin D3 supplementation can raise calcium levels to an excessively high level. I have found this to be especially true in African American patients. Testing for 1,25-dihyroxy Vitamin D3, PTH and calcium blood levels should therefore become a part of every woman’s regular blood work.
A growing number of researchers who have widely studied Vitamin D3 are almost begging the general public to consume more of this important nutrient. Due to Vitamin D3’s high safety profile in doses up to 10,000 IU per day and because of the wide role it plays in our health, consuming 2,000 to 4,000 IU per day of this nutrient at times of the year when sunlight is scarce is a prudent way to improve overall health.
These Vitamin D3 capsules are wonderful.
My doctor informed me that I was Vitamin D3 deficient a while back so the first thing I did was check for NOW brand D3, because I know I can trust their brand after years of use.
These 5,000 IU capsules aren't any bigger than 1,000 IU or 2,000 IU capsules I've seen.
There's no strange smell, there's no bad taste, and they're small so they're easy to swallow.
If you need Vitamin D in a 5,000 IU dose, these are perfect for me, so they would hopefully work for you too!