This is a manual which aims to provide a biological approach to nerve injuries, concentrating on the upper extremity, to bridge the gap between neuroscientists and clinicians, and to stimulate improved methods of treatment. It describes the state-of-the-art, outling current understanding of the pathophysiology of nerve damange and stressing the implications of surgical management. Empahsis is given to areas such as neurotrophic factors and intraneural microcirculation and diffusion barriers.
