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Neural Networks and Genome Informatics, Volume 1 (Methods in Computational Biology and Biochemistry) [Hardcover]

C.H. Wu (Editor), J.W. McLarty (Editor)
4.3 out of 5 stars  See all reviews (3 customer reviews)


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Book Description

October 5, 2000 0080428002 978-0080428000 1
This book is a comprehensive reference in the field of neural networks and genome informatics. The tutorial of neural network foundations introduces basic neural network technology and terminology. This is followed by an in-depth discussion of special system designs for building neural networks for genome informatics, and broad reviews and evaluations of current state-of-the-art methods in the field. This book concludes with a description of open research problems and future research directions.

Product Details

  • Hardcover: 220 pages
  • Publisher: Elsevier Science; 1 edition (October 5, 2000)
  • Language: English
  • ISBN-10: 0080428002
  • ISBN-13: 978-0080428000
  • Product Dimensions: 9.6 x 6.7 x 0.6 inches
  • Shipping Weight: 1.2 pounds
  • Average Customer Review: 4.3 out of 5 stars  See all reviews (3 customer reviews)
  • Amazon Best Sellers Rank: #4,713,835 in Books (See Top 100 in Books)

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Average Customer Review
4.3 out of 5 stars (3 customer reviews)
 
 
 
 
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7 of 7 people found the following review helpful:
5.0 out of 5 stars Timely text for beginners and experts alike, June 14, 2001
By A Customer
This review is from: Neural Networks and Genome Informatics, Volume 1 (Methods in Computational Biology and Biochemistry) (Hardcover)
In contrast to so many other bioinformatics books this one is written by genuine experts who have first-hand experience in both computer science and modern biology.

Each chapter is a masterpiece of clarity and good judgement in selection of topics to be covered. The book contains a large glossary of terms which makes it accessible for multidisciplinary readers. The authors made considerable effort to provide unbiased selection of most appropriate references following each chapter. This makes the book a superb research monograph for the specialists in addition to being a suitable text for educated beginners.

The book should be read by computer scientists who contemplate doing work in bioinformatics as well as by biologists who contemplate working in bioinformatics. Anybody who wants to design neural networks for specific biological applications will benefit the most from reading this text. Anybody who just wants to understand how and why neural networks can be used in biology will benefit from reading this book as well. Practicing computational biologists and bioinformaticians should have this book available as a desk reference. Psychologists, cognitive and social scientists who are interested in neural networks and artificial learning will likely benefit from reading this book as well.

I hasten to add that it would be really good for the book and for its readers if the publisher considered either lowering the price or printing a cheaper paperback edition.

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5 of 6 people found the following review helpful:
5.0 out of 5 stars GreatBook, May 30, 2001
By A Customer
This review is from: Neural Networks and Genome Informatics, Volume 1 (Methods in Computational Biology and Biochemistry) (Hardcover)
This is a book that comes out at the right time, a time when tons of information from genomics and several improved analysis tools based on great ideas are both becoming available. I believe readers from a broad range of academic background will benefit from the integration of knowledges from genome informatics, statistics, computer science, engineering, and mathmatics, a feature that this book exemplifies.
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3 of 5 people found the following review helpful:
3.0 out of 5 stars Good as a literature survey, May 30, 2002
This review is from: Neural Networks and Genome Informatics, Volume 1 (Methods in Computational Biology and Biochemistry) (Hardcover)
This book serves well to introduce the reader to the literature on the applications of neural networks to bioinformatics. It falls short however in giving an in-depth view of how neural networks operate and does not include any source code. Performance issues with the use of neural networks in genome informatics should have been given a more careful treatment. Considering its price, this is disappointing. A reader could obtain the required reading material on this subject from an online search. An instructor in a course in bioinformatics might use this book as a reference source however. Those who have used neural networks in other fields might be able to use the book as a guide to applying them to genome informatics. Thus the book could be viewed as a (very expensive) literature review article, but it does include some interesting remarks at various places: 1. Amino acid groupings that are found automatically by a Kohonen self-organizing map. 2. Feature representation and input encoding. 3. The discussion on cross-validation. 4. The discussion on protein secondary structure prediction. Genetic algorithms are mentioned here, so readers not familiar with these will have to gain the background elsewhere.
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Inside This Book (learn more)
First Sentence:
Driven largely by the vast amounts of DNA sequence data, a new field of computational molecular biology has emerged: genome informatics. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
coding region recognition, classification artificial neural system, weight matrix method, protein family classification, nucleic acid sequence analysis, input variable selection, pruned network, promoter prediction, folding classes, protein secondary structure prediction, translational initiation sites, gene recognition, indirect encoding, genome informatics, network pruning, signal peptide prediction, two output units, sequence discrimination, one output unit, training multilayer perceptrons, optimal brain surgeon, radial basis function networks, sequence windows, neural network design, single output unit
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nucleic Acids Res, Comput Appl Biosci, Mol Biol, Protein Sci, Methods Enzymol, New York, Comput Biol, Proc Natl Acad Sci, Protein Eng, Adv Neural Inf Process Syst, Neural Comput, Neural Information Processing Systems, Protein Chem, Coding Recognition, Comput Chem, Pac Symp Biocomput, San Mateo, Van Nostrand Reinhold, Adam Hilger, Biomol Struct Dyn, Boca Raton, Classification Networks, Kohonen Freq, Most Probable, Mot Biol
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