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The Neural Crest in Development and Evolution [Hardcover]

Brian K. Hall (Author)


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Book Description

July 30, 1999
This book is about the neural crest and neural crest cells, dealing with their discovery, their embryological and evolutionary origins, their cellular derivatives - in both agnathan and jawed vertebrates or gnathostomes - and the broad topics of migration and differentiation in normal development. Knowledge of the development and evolution of the neural crest sheds light on many of the oldest unanswered questions in developmental biology, such as: What is the role of the germ layers in early embryogenesis? How does the nervous systems develop? How does the vertebrate head arise developmentally and how did it arise evolutionary? How do growth factors and Hox genes direct cell differentiation and embryonic patterning? Cells from the neural crest are also associated with many developmental abnormalities. The book includes discussions of what goes wrong when development is misdirected by mutations, or by exposure of embryos to exogenous agents such as drugs, alcohol, or excess vitamin A. The book also includes discussions of tumors (neurocristopathies) and syndromes and birth defects involving neural crest cells.

Product Details

  • Hardcover: 313 pages
  • Publisher: Springer; 1 edition (July 30, 1999)
  • Language: English
  • ISBN-10: 0387987029
  • ISBN-13: 978-0387987026
  • Product Dimensions: 9.5 x 6.4 x 0.8 inches
  • Shipping Weight: 15.2 ounces
  • Amazon Best Sellers Rank: #3,951,634 in Books (See Top 100 in Books)

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Inside This Book (learn more)
First Sentence:
In 1868, Wilhelm His (1831-1904), a Swiss embryologist, identified a band of cells sandwiched between the developing neural tube and the future epidermal ectoderm in neurula-stage chick embryos as the source of spinal and cranial ganglia. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
ral crest cells, visceral arch cartilages, rostral trunk neural crest, clonal cell culture, crest cell migration, skeletogenic neural crest, neural crest induction, placodal ectoderm, neural crest cell development, homoiogenetic induction, neural crest markers, neural crest arises, fourth germ layer, neural crest cell differentiation, nodose placode, visceral cartilages, visceral arch skeleton, defective neural crest, epidermal ectoderm, neural keel, cardiac neural crest, visceral arches, fin mesenchyme, mandibular mesenchyme, arch ectoderm
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Julia Platt, Joseph Merrick, The Company of Biologists Ltd, Treacher Collins, United States, Elephant Man, John Wiley, Wiley-Liss Inc, David Newth, Gavin de Beer, Patrick Tam
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