This volume presents a critical appraisal of the neurological literature on neuromuscular disease from an evidence-based perspective. Writing in a readable, accessible style, the author considers, in detail, a broad range of the published literature relevant not only to questions of treatment, but also to issues of diagnosis and prognosis. Through a series of questions and answers concerning specific neuromuscular disorders, each chapter critiques the best available evidence to illustrate strengths and weaknesses of the data and make the reader aware of the quality of clinical research studies in general. Introductory chapters facilitate this learning process by elucidating the epidemiological and biostatistical issues pertinent to diagnosis, treatment, and prognosis. A broad range of disorders of the anterior horn cell, nerve roots, peripheral nerves, neuromuscular junction, and muscle are critically appraised and discussed.
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Editorial Reviews
Review
From the reviews: "The book religiously adheres to empirical evidence from studies of clinical evaluation and treatment of neuromuscular disease. … its writing is crystal clear, with nice summaries in each section and at the end of each chapter. … it is a superb tool in conjunction with traditional teaching or when used by practitioners or teachers. … it is an outstanding source of the actual evidence, carefully reviewed and discussed, free of flashy distraction. As such, I will turn to it frequently as a trusted reference." (S. Claiborne Johnston, Muscle & Nerve, February, 2007) "...useful for non-specialised and specialised neurologists treating neuromuscular disorders, and especially for those under the pressures of medicine who have difficulties in gathering detailed information required to reach unbiased conclusions." -Schweizer Archiv Fur Neurologie und Psychiatrie "The information … constitutes an easily accessible resource for the busy practitioner or the novice in the field, because the reader can select questions of interest without needing to read a whole review on the subject. The format is didactic and keeps the reader engaged. … this book can provide easy reading for the busy general neurologist and offers quick and succinct answers to questions raised in everyday practice regarding the diagnosis and management of common neuromuscular problems." (Marinos C. Dalakas, The New England Journal of Medicine, May, 2007)
From the Back Cover
Evidence-based medical practice stresses the examination of evidence from clinical research as the basis for clinical decision making, rather than relying on unsystematic clinical experience and pathophysiological rationale. In Neuromuscular Disease: Evidence and Analysis in Clinical Neurology, Michael Benatar, MBChB, demonstrates this approach in the case of neuromuscular disease with a critical appraisal of the neurological literature. Writing in a readable, accessible style, the author considers, in detail, a broad range of the published literature relevant not only to questions of treatment, but also to issues of diagnosis and prognosis of neuromuscular disease. Through a series of questions and answers concerning specific neuromuscular disorders, each chapter critiques the best available evidence to illustrate strengths and weaknesses of the data and make the reader aware of the quality of clinical research studies in general. Introductory chapters facilitate this learning process by elucidating the epidemiological and biostatistical issues pertinent to diagnosis, treatment, and prognosis. A broad range of disorders of the anterior horn cell, nerve roots, peripheral nerves, neuromuscular junction, and muscle are critically appraised and discussed. Original and illuminating, Neuromuscular Disease: Evidence and Analysis in Clinical Neurology clarifies the available evidence base for why neurologists practice as they do in neuromuscular disease and suggests a healthy degree of skepticism about claims that are made without supporting evidence.
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Inside This Book
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Key Phrases - Statistically Improbable Phrases (SIPs):
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chronic reinnervation changes, demyelinating physiology, recurrent myoglohinuria, segmental neurological deficits, nonsystemic vasculitis, fixed muscle weakness, pharmacological remission, median motor conduction velocity, single randomized study, typical clinical phenotype, nonnecrotic muscle fibers, axonal physiology, neurological disability score, patient blinding, muscle carnitine deficiency, peripheral nerve vasculitis, forearm exercise test, global symptom score, muscle strength score, incorporation bias, complete areflexia, asymmetric polyneuropathy, glycosylated hemoglobin concentration, proximal nerve segments, rural nerve biopsy Key Phrases - Capitalized Phrases (CAPs): (learn more)
Clinical Neurology, Muscle Nerve, Ann Neurol, Neurol Neurosurg Psychiatry, Arch Neurol, Neurol Sci, Humana Press Inc, Acta Neurol Scand, Hand Surg, Acad Sci, Paraproteinemic Neuropathies, American Academy of Neurology, Arthritis Rheum, Bone Joint Surg, Electromyogr Clin Neurophysiol, Cochrane Database Systematic Reviews, Eur Neurol, Unclear Unclear Adequate Unclear Adequate, Arch Phys Med Rehabil, Clin Orthop Relat Res, Cochrane Database Syst Rev, Med Genet, Neurontuscular Disease, New York, Air Force New!
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Front Cover | Table of Contents | First Pages | Index | Surprise Me!
chronic reinnervation changes, demyelinating physiology, recurrent myoglohinuria, segmental neurological deficits, nonsystemic vasculitis, fixed muscle weakness, pharmacological remission, median motor conduction velocity, single randomized study, typical clinical phenotype, nonnecrotic muscle fibers, axonal physiology, neurological disability score, patient blinding, muscle carnitine deficiency, peripheral nerve vasculitis, forearm exercise test, global symptom score, muscle strength score, incorporation bias, complete areflexia, asymmetric polyneuropathy, glycosylated hemoglobin concentration, proximal nerve segments, rural nerve biopsy Key Phrases - Capitalized Phrases (CAPs): (learn more)
Clinical Neurology, Muscle Nerve, Ann Neurol, Neurol Neurosurg Psychiatry, Arch Neurol, Neurol Sci, Humana Press Inc, Acta Neurol Scand, Hand Surg, Acad Sci, Paraproteinemic Neuropathies, American Academy of Neurology, Arthritis Rheum, Bone Joint Surg, Electromyogr Clin Neurophysiol, Cochrane Database Systematic Reviews, Eur Neurol, Unclear Unclear Adequate Unclear Adequate, Arch Phys Med Rehabil, Clin Orthop Relat Res, Cochrane Database Syst Rev, Med Genet, Neurontuscular Disease, New York, Air Force New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
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