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Neuronal Substrates of Sleep and Epilepsy
 
 
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Neuronal Substrates of Sleep and Epilepsy [Hardcover]

Mircea Steriade (Author)

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Book Description

June 23, 2003
Conventional wisdom assumes that sleep is a resting state of the brain, with negligible activity of cortical neurons. Here, the author brings new evidence favoring the idea that during sleep, memory traces acquired while awake are consolidated. Mircea Steriade focuses on the coalescence of different sleep rhythms in interacting corticothalamic networks and on three types of paroxysmal disorders: spike-wave seizures as in absence epilepsy, Lennox-Gastaut seizures, and temporal-lobe epilepsy. Many physiological correlates of waking and sleep states as well as diverse types of epileptic seizures are also discussed.

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Editorial Reviews

Review

"...the field of neuroscience is in the professor's debt for writing it...worth the read." Neurology

Book Description

Sleep and epilepsy are common bedfellows, as a series of epileptic fits can occur during the state of sleep with slow electroencephalogram waves. The author describes for neuroscientists and clinicians the signs of different states of vigilance (waking, slow wave, and dreaming sleep), the neuronal operations that account for these normal states and the cellular mechanisms underlying diverse types of epileptic seizures. Readers are presented with comprehensive data and discussion, based on the author's research. This is the first book to explore the inter-related topics of sleep and epilepsy.

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Inside This Book (learn more)
First Sentence:
This book is essentially devoted to analyses of neuronal substrates underlying sleep with low-frequency oscillations, so-called sleep with synchronized electroencephalogram (EEG) or resting sleep [1], and a series of seizures that preferentially develop during this state of sleep. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
isolated cortical slabs, intracortical synchrony, cortical augmenting responses, slow sleep oscillation, thalamic stimuli, brain figurine, cat under barbiturate anesthesia, intrathalamic augmenting responses, athalamic animals, intercalated cell masses, neocortical slabs, cat under urethane anesthesia, spindle sequences, cortical slow oscillation, thalamic centrolateral, brain deafferentation, thalamic lateroposterior, intralaminar centrolateral, anterior thalamic neurons, other sleep rhythms, chronically implanted cat, progressive hyperpolarization, steady hyperpolarization, slow cortical oscillation, intralaminar neurons
Key Phrases - Capitalized Phrases (CAPs): (learn more)
John Hughlings Jackson, Lopes da Silva, Patterns of Lennox-Gastaut
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