Perhaps the most astonishing accomplishment of human brain activity has been the invention of scientific methods for transforming limited and distorted information about the outer world, as it is perceived through sensory processes, into conceptual models that have given modern man unprecedented control over his physical environment. A challenging riddle now at the center of the stage of life science, if not of all science, is the following: Can the brain achieve an equally scientific understanding of itself? In this search for understanding, the living brain is at once a physical object to be investigated and the physical source of those experiences that make up the mental life of the working scientist.
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