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New Concepts in AIDS Pathogenesis
 
 
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New Concepts in AIDS Pathogenesis [Hardcover]

Luc Montagnier (Author)

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Book Description

0824791274 978-0824791278 August 2, 1993 1

This resource offers comprehensive explanations of current theories on the pathogenesis of AIDS, examining in detail current data on the role that HIV and its possible cofactors play in the decline of immune system function and the progressive depletion of T lymphocytes. Information is provided on mycoplasmas - a potentially critical component in virus replication and immune activation.;Revealing research studies in support of the theoretical approaches presented, this volume: updates the mechanisms of HIV latency and activation of expression at both the viral and cellular levels in the human and primate systems; emphasizes the role of cytokines in the dysfunction of the immune and central nervous systems; describes the mechanisms of immune activation that result in anergy and programmed cell death involving the viral external glycoprotein and possible other foreign antigens or superantigens; and explicates original hypotheses on pathogenesis where virus glycoproteins may mimic allogenic stimulation and disturb the immune system network.;This reference is intended for immunologists, infectious disease specialists, microbiologists, virologists, molecular and cell biologists, parasitologists and pathologists.


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Editorial Reviews

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. . .well organized and edited.
---The New England Journal of Medicine
. . .a stimulating update.
---Journal of Scientific & Industrial Research

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Inside This Book (learn more)
First Sentence:
A striking feature of the clinical presentation of AIDS is the discrete stages of disease progression observed in most patients (1). Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
programmed cell death hypothesis, allogeneic challenge, neuronotoxic activity, uninfected monocytes, allogeneic effect, promonocytic cells, human immunodeficiency virus expression, chronically infected cells, viral activation, immunodeficiency virus isolate, superantigen encoded, allogeneic cells, infected cell lines, allogeneic lymphocytes, nef gene, syncytia formation, viral expression, cell decline, cell tropism, membrane expression, mangabey monkeys, autoimmune mice, viral latency, human immunodeficiency virus type, clonal anergy
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Exp Med, Proc Natl Acad Sci, Immunol Today, Clin Invest, Infect Dis, Res Hum Retrovir, Clin Exp Immunol, New York, Ann Neurol, Ann Intern Med, Clin Immunol Immunopathol, Related Animal Diseases, Immunol Rev, Infect Immun, Retroviruses of Human, Colloque des Cent Gardes, Sem Immunol, Van Noesel, Annu Rev Immunol, Becton Dickinson, Biol Chem, Cell Immunol, Curr Biol, Dal Canto, Hum Pathol
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