- Nizoral hair shampoo for anti dandruff controls the flaking, scaling and itching associated with dandruff.
- freedom will go to your head.
- Protect from light and freezing.
- Non-prescription strength.
Product Features |
Frequently Bought Together
Important Information
Indications
Controls flaking, scaling and itching associated with dandruff.
Ingredients
Active Ingredient: Ketoconazole (1%). Inactive Ingredients: Acrylic Acid Polymer (Carbomer 1342), Butylated Hydroxytoluene, Cocamide MEA, FD&C Blue 1, Fragrance, Glycol Distearate, Polyquaternium-7, Quaternium-15, Sodium Chloride, Sodium Cocoyl Sarcosinate, Sodium Hydroxide and/or Hydrochloric Acid, Sodium Laureth Sulfate, Tetrasodium EDTA, Water.
Directions
Adults and Children 12 Years and Over: Wet hair thoroughly; apply shampoo, generously lather, rinse thoroughly. Repeat; use ever 3-4 days for up to 8 weeks or as directed by a doctor. Then use only as needed to control dandruff. Children Under 12 Years: Ask a doctor. Store between 35 and 86 degrees F (2 and 30 degrees C). Protect from light. Protect from freezing.
Controls flaking, scaling and itching associated with dandruff.
Ingredients
Active Ingredient: Ketoconazole (1%). Inactive Ingredients: Acrylic Acid Polymer (Carbomer 1342), Butylated Hydroxytoluene, Cocamide MEA, FD&C Blue 1, Fragrance, Glycol Distearate, Polyquaternium-7, Quaternium-15, Sodium Chloride, Sodium Cocoyl Sarcosinate, Sodium Hydroxide and/or Hydrochloric Acid, Sodium Laureth Sulfate, Tetrasodium EDTA, Water.
Directions
Adults and Children 12 Years and Over: Wet hair thoroughly; apply shampoo, generously lather, rinse thoroughly. Repeat; use ever 3-4 days for up to 8 weeks or as directed by a doctor. Then use only as needed to control dandruff. Children Under 12 Years: Ask a doctor. Store between 35 and 86 degrees F (2 and 30 degrees C). Protect from light. Protect from freezing.
Product Description
Controls flaking, scaling and itching. The freedom will go to your head. Non-prescription strength. A-D Ketoconazole shampoo 1%. Made in Italy.
Product Details
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Customer Reviews
Most Helpful Customer Reviews
205 of 205 people found the following review helpful
Amazon Verified Purchase
Pros: Works wonders on persistent flaking of dandruff, leaves hair clean
Cons: Small size bottle for the price. Tingling Side effects. Has strong chemicals.
Bottom line: If you've tried everything and nothing works...this is the one to get. If you haven't tried everything, there are more natural shampoo available with less side effects.
The story: Only after 2 days of use, my dandruff is gone! Head and shoulders took 5 days but also experience tremendous hair loss when using Head and Shoulders. Both leaves my hair a little dry and a weird tingling feeling. I also noticed a lengthy ingredient list with many warnings.
So you know that this is prescription strength that is available over the counter. I will list the Drug facts later.
If you're experience dandruff and nothing works, definitely try this. If you haven't try everything, try more organic shampoo such as Pura d'or Anti-dandruff: Premium Organic Shampoo (16 fl. oz.) or any other shampoo with Tea tree oil or Zinc ingredients in it (you can probably make your own too). This is not as strong or powerful as Nizoral but it works, is safer and has no side effects.
NIZORAL A-D Ketoconazole Shampoo 1%
Drug Facts
Active ingredients Purpose
Ketoconazole 1%..........................................................................Anti-dandruff shampoo
Uses controls flaking, scaling and itching associated with dandruff
Warnings
For external use only
Do not use
on scalp that is broken or inflamed
if you are allergic to ingredients in this product
When using this product
avoid contact with eyes
if product gets into eyes, rinse thoroughly with water
Stop use and ask a doctor if
rash appears
condition worsens or does not improve in 2-4 weeks
If pregnant or breast-feeding, ask a doctor before use.
Keep out of the reach of children. If swallowed, get medical help or contact a Poison Control Center
right away.
Directions
adults and children wet hair thoroughly
12 years and over apply shampoo, generously lather, rinse thoroughly. Repeat
use every 3-4 days for up to 8 weeks or as directed by a doctor.
Then use only as needed to control dandruff
children under 12 years ask a doctor
NIZORAL® A-D (continued)
Other information
store between 35° and 86°F (2° and 30°C)
protect from light protect from freezing
see top panel for lot number and expiration date
Inactive ingredients acrylic acid polymer (carbomer 1342), butylated hydroxytoluene, cocamide MEA,
FD&C Blue #1, fragrance, glycol distearate, polyquaternium-7, quaternium-15, sodium chloride, sodium
cocoyl sarcosinate, sodium hydroxide and/or hydrochloric acid, sodium laureth sulfate, tetrasodium
EDTA, water
Questions or comments? call 1-800-962-5357
©McN-PPC, Inc.
Distributed by:
MCNEIL CONSUMER HEALTHCARE
DIVISION OF McNEIL-PPC, INC.
FORT WASHINGTON, PA 19034 USA
Made in Italy
US Patent Nos. 4,335,125; 4,942,162 and 5,456,851
Cons: Small size bottle for the price. Tingling Side effects. Has strong chemicals.
Bottom line: If you've tried everything and nothing works...this is the one to get. If you haven't tried everything, there are more natural shampoo available with less side effects.
The story: Only after 2 days of use, my dandruff is gone! Head and shoulders took 5 days but also experience tremendous hair loss when using Head and Shoulders. Both leaves my hair a little dry and a weird tingling feeling. I also noticed a lengthy ingredient list with many warnings.
So you know that this is prescription strength that is available over the counter. I will list the Drug facts later.
If you're experience dandruff and nothing works, definitely try this. If you haven't try everything, try more organic shampoo such as Pura d'or Anti-dandruff: Premium Organic Shampoo (16 fl. oz.) or any other shampoo with Tea tree oil or Zinc ingredients in it (you can probably make your own too). This is not as strong or powerful as Nizoral but it works, is safer and has no side effects.
NIZORAL A-D Ketoconazole Shampoo 1%
Drug Facts
Active ingredients Purpose
Ketoconazole 1%..........................................................................Anti-dandruff shampoo
Uses controls flaking, scaling and itching associated with dandruff
Warnings
For external use only
Do not use
on scalp that is broken or inflamed
if you are allergic to ingredients in this product
When using this product
avoid contact with eyes
if product gets into eyes, rinse thoroughly with water
Stop use and ask a doctor if
rash appears
condition worsens or does not improve in 2-4 weeks
If pregnant or breast-feeding, ask a doctor before use.
Keep out of the reach of children. If swallowed, get medical help or contact a Poison Control Center
right away.
Directions
adults and children wet hair thoroughly
12 years and over apply shampoo, generously lather, rinse thoroughly. Repeat
use every 3-4 days for up to 8 weeks or as directed by a doctor.
Then use only as needed to control dandruff
children under 12 years ask a doctor
NIZORAL® A-D (continued)
Other information
store between 35° and 86°F (2° and 30°C)
protect from light protect from freezing
see top panel for lot number and expiration date
Inactive ingredients acrylic acid polymer (carbomer 1342), butylated hydroxytoluene, cocamide MEA,
FD&C Blue #1, fragrance, glycol distearate, polyquaternium-7, quaternium-15, sodium chloride, sodium
cocoyl sarcosinate, sodium hydroxide and/or hydrochloric acid, sodium laureth sulfate, tetrasodium
EDTA, water
Questions or comments? call 1-800-962-5357
©McN-PPC, Inc.
Distributed by:
MCNEIL CONSUMER HEALTHCARE
DIVISION OF McNEIL-PPC, INC.
FORT WASHINGTON, PA 19034 USA
Made in Italy
US Patent Nos. 4,335,125; 4,942,162 and 5,456,851
48 of 50 people found the following review helpful
I decided to make my own ketoconazole shampoo because I refuse to pay the price gougers on Amazon. ($109, really?!) My son has severe scalp seborrheic dermatitis due to the rampant hormones of puberty, and our pediatrician recommended Nizoral. I did a literature search to learn the chemistry. See Useful Articles below if you need some juicy bedtime reading ;-)
First, if helpful, here's my layman's understanding of how various anti-dandruff shampoos work (since I had to do all that legwork anyway):
Dandruff in general is accelerated skin cell maturation/shedding cycles (keratinization) and the "disorganized" attachment of lipid droplets to skin cells as they migrate to the outer layer of the scalp, thereby forming itchy flakes. Seborrheic dermatitis is the population explosion of opportunistic Malassezia fungus feasting on increased scalp sebum in addition to the above conditions. There are 7 species of Malassezia, and one in particular loves scalp sebum because it's rich in the saturated hard fats: triglycerides and cholesterol.
Ketoconazole is a broad spectrum antifungal that directly attacks Malassezia by causing their cell membranes to break down. It's also anti-inflammatory and reduces sebum. The mechanisms of action of selenium sulfide and zinc pyrithione are less well understood. Both reduce Malassezia count and scalp sebum, but basically tackle dandruff by other routes. Zinc pyrithione normalizes the abnormal keratin structure of the stratum corneum resulting in fewer lipid inclusions between skin cells, and therefore fewer flakes. Selenium sulfide reduces the cell turnover rate, which is normally 28-30 days but has been observed to be a week or less in cases of dandruff. Salicylic acid breaks down skin cell-sebum plaques or flakes; in other words, it's symptom management and can be useful in combination with other active ingredients. I passed over tar and sulfur shampoos as my son won't use them. Tea tree oil is out for us; it's a phytoestrogen that's documented to be feminizing if used regularly by boys.
Making ketoconazole shampoo:
In summary, antifungal medications are lipophilic, so you need a fat solvent -- or so I thought until I tried fish pills--- followed by an emulsifier to keep ketoconazole dispersed evenly in your shampoo.
The important issue is formulating ketoconazole at one percent. That begs the question: one percent of what? At one point in the shortage, we had been able to get the 2% Nizoral from the UK thru Amazon, and I saved the leaflet which stated: "The active ingredient in 1 g of Nizoral Dandruff Shampoo is ketoconazole 20mg." Therefore the 1% represents a percentage of VOLUME. This saves us from the impossible task of titration.
This shampoo has worked beautifully. Materials needed:
(1) Aqua Fungus 200mg ketoconazole tablets. 30 tablets, for fish, from Amazon $19.99 + $5 shipping. I figured fish pills just might be water soluable. Indeed they are.
(2) Polysorbate-80, 2 ounces, $2. It's a safe, low toxicity solvent/emulsifier commonly found in food and shampoo. It's inexpensive and readily available from DIY cosmetics websites such as Making Cosmetics, Lotion Crafter, Garden of Wisdom, etc.
(3) A bottle of shampoo with a refillable opening. I used Organix Morocco Argan Oil Shampoo, 385 ml or 13 fluid ounces. I chose argan oil because it's a lipid and a known hair softener that eliminates the need for a conditioner.
(4) A food scale. If you don't have one, you can just use as much shampoo as I did.
(5) A long clean stick for stirring. I used a stainless steel escargot fork because it's easy to sterilize.
(6) A sterile pyrex measuring cup large enough to hold most of your shampoo.
Procedure:
(1) I bought a 385 ml bottle of shampoo, therefore 1% volume-wise would be 3.8 or 3.9 ml. The pills are dosaged in milligrams, so you need a ml to mg coverter. Google that, and count out the required number of pills on your food scale. I used 11 pills.
(2) Fold a thick piece of paper in half. You don't want it to tear. The crease in the paper will help you transfer the crushed pills very neatly. I used a new Papyrus notecard. Put the pills along the fold and crush them as fine as possible with a small hammer or similar.
(3) Put the powder in a small, sterile cup, such as a shotglass. Add just enough distilled or boiled/cooled water to mix it thoroughly. Add a couple of teaspoons of polysorbate 80 and stir.
(4) Pour your shampoo into the pyrex cup first and then add the crushed pill mixture. Stir well and pour back into bottle.
If your shampoo separates from using too much water, shake the bottle before use. It's easier than a do-over.
It might also be helpful to...
-- leave the shampoo on 5 minutes before rinsing.
-- shampoo your hairbrush also
-- change pillowcases frequently
Useful Articles:
Drug delivery strategies for improved azole antifungal action, W.Yang, et al, November, 2008. informahealthcare.com
Design and Development of Topical Microemulsion for Poorly Water-Soluble Antifungal Agents, P. Paranajoti, et al, Journal of Applied Research,2002
An Overview of Medicated Shampoos used in Dandruff Treatment, A. Sanfilippo & J. English. ptcommunity.com
Dandruff has an Altered Stratum Corneum Ultrastructure that is Improved with Zinc Pyrithione Shampoo, R.R. Warner, et al., Journal of the American Academy of Dermatology, Vol 45, Number 6.
First, if helpful, here's my layman's understanding of how various anti-dandruff shampoos work (since I had to do all that legwork anyway):
Dandruff in general is accelerated skin cell maturation/shedding cycles (keratinization) and the "disorganized" attachment of lipid droplets to skin cells as they migrate to the outer layer of the scalp, thereby forming itchy flakes. Seborrheic dermatitis is the population explosion of opportunistic Malassezia fungus feasting on increased scalp sebum in addition to the above conditions. There are 7 species of Malassezia, and one in particular loves scalp sebum because it's rich in the saturated hard fats: triglycerides and cholesterol.
Ketoconazole is a broad spectrum antifungal that directly attacks Malassezia by causing their cell membranes to break down. It's also anti-inflammatory and reduces sebum. The mechanisms of action of selenium sulfide and zinc pyrithione are less well understood. Both reduce Malassezia count and scalp sebum, but basically tackle dandruff by other routes. Zinc pyrithione normalizes the abnormal keratin structure of the stratum corneum resulting in fewer lipid inclusions between skin cells, and therefore fewer flakes. Selenium sulfide reduces the cell turnover rate, which is normally 28-30 days but has been observed to be a week or less in cases of dandruff. Salicylic acid breaks down skin cell-sebum plaques or flakes; in other words, it's symptom management and can be useful in combination with other active ingredients. I passed over tar and sulfur shampoos as my son won't use them. Tea tree oil is out for us; it's a phytoestrogen that's documented to be feminizing if used regularly by boys.
Making ketoconazole shampoo:
In summary, antifungal medications are lipophilic, so you need a fat solvent -- or so I thought until I tried fish pills--- followed by an emulsifier to keep ketoconazole dispersed evenly in your shampoo.
The important issue is formulating ketoconazole at one percent. That begs the question: one percent of what? At one point in the shortage, we had been able to get the 2% Nizoral from the UK thru Amazon, and I saved the leaflet which stated: "The active ingredient in 1 g of Nizoral Dandruff Shampoo is ketoconazole 20mg." Therefore the 1% represents a percentage of VOLUME. This saves us from the impossible task of titration.
This shampoo has worked beautifully. Materials needed:
(1) Aqua Fungus 200mg ketoconazole tablets. 30 tablets, for fish, from Amazon $19.99 + $5 shipping. I figured fish pills just might be water soluable. Indeed they are.
(2) Polysorbate-80, 2 ounces, $2. It's a safe, low toxicity solvent/emulsifier commonly found in food and shampoo. It's inexpensive and readily available from DIY cosmetics websites such as Making Cosmetics, Lotion Crafter, Garden of Wisdom, etc.
(3) A bottle of shampoo with a refillable opening. I used Organix Morocco Argan Oil Shampoo, 385 ml or 13 fluid ounces. I chose argan oil because it's a lipid and a known hair softener that eliminates the need for a conditioner.
(4) A food scale. If you don't have one, you can just use as much shampoo as I did.
(5) A long clean stick for stirring. I used a stainless steel escargot fork because it's easy to sterilize.
(6) A sterile pyrex measuring cup large enough to hold most of your shampoo.
Procedure:
(1) I bought a 385 ml bottle of shampoo, therefore 1% volume-wise would be 3.8 or 3.9 ml. The pills are dosaged in milligrams, so you need a ml to mg coverter. Google that, and count out the required number of pills on your food scale. I used 11 pills.
(2) Fold a thick piece of paper in half. You don't want it to tear. The crease in the paper will help you transfer the crushed pills very neatly. I used a new Papyrus notecard. Put the pills along the fold and crush them as fine as possible with a small hammer or similar.
(3) Put the powder in a small, sterile cup, such as a shotglass. Add just enough distilled or boiled/cooled water to mix it thoroughly. Add a couple of teaspoons of polysorbate 80 and stir.
(4) Pour your shampoo into the pyrex cup first and then add the crushed pill mixture. Stir well and pour back into bottle.
If your shampoo separates from using too much water, shake the bottle before use. It's easier than a do-over.
It might also be helpful to...
-- leave the shampoo on 5 minutes before rinsing.
-- shampoo your hairbrush also
-- change pillowcases frequently
Useful Articles:
Drug delivery strategies for improved azole antifungal action, W.Yang, et al, November, 2008. informahealthcare.com
Design and Development of Topical Microemulsion for Poorly Water-Soluble Antifungal Agents, P. Paranajoti, et al, Journal of Applied Research,2002
An Overview of Medicated Shampoos used in Dandruff Treatment, A. Sanfilippo & J. English. ptcommunity.com
Dandruff has an Altered Stratum Corneum Ultrastructure that is Improved with Zinc Pyrithione Shampoo, R.R. Warner, et al., Journal of the American Academy of Dermatology, Vol 45, Number 6.
21 of 24 people found the following review helpful
For everyone trying to find these it honestly makes a lot more sense to look at either alternative products with ketoconazole, or to simply import from places where this apparently isn't in dire shortage like the UK. In the UK the 1% shampoo is branded Nizorelle instead of Nizoral, whereas the 2% strength is called Nizoral there. The price of Nizorelle is still very reasonable so if you have to get ahold of this I'd look on ebay and the like to buy a small bottle or two to tide you over until U.S. supply is restored.
Regenepure DR would be an alternate product that's sold by some sellers right here on Amazon, unfortunately it's also rather expensive but not a $40+ ripoff. The very cheapest alternative I could find containing Ketoconazole was oddly, pet shampoo, but the problem is that those also contain somewhat harsh anti-bacterial agents like chlorhexidine, and may also make for plain lousy human shampoos. If you can find a formulation that's human-safe that doesn't contain harsh chemicals and you're willing to risk using an animal shampoo this is probably the cheapest (and admittedly the worst and vaguely dangerous) alternative.
Regenepure DR would be an alternate product that's sold by some sellers right here on Amazon, unfortunately it's also rather expensive but not a $40+ ripoff. The very cheapest alternative I could find containing Ketoconazole was oddly, pet shampoo, but the problem is that those also contain somewhat harsh anti-bacterial agents like chlorhexidine, and may also make for plain lousy human shampoos. If you can find a formulation that's human-safe that doesn't contain harsh chemicals and you're willing to risk using an animal shampoo this is probably the cheapest (and admittedly the worst and vaguely dangerous) alternative.
Most Recent Customer Reviews
Great shampoo
This product started working on the first use. I noticed that my scalp wasn't itchy and didn't have dandruff flakes on my clothes. Read more
Published 3 days ago by Cmelle
Highly Recommended
With just first tried, there's no more visible dandruff! Though I felt a bit itchy during the first week of usage, eventually everything went well and my dandruff problem was... Read more
Published 11 days ago by chris
Finally after wasted time...
I have found a product that works on my scalp. Between 2010-11, I have used H&S, Selsun Blue and Yellow, Neutrogena T-Sal and T-Gel, KeriCare Dry Scalp, Paul Mitchell Tea Tree,... Read more
Published 25 days ago by T. M. Wiggins
Wow
I used Head and shoulders and Nature's gate calming shampoo before using Nizoral. Head and shoulders was extremely harsh on my head and it actually turned my bangs into a lighter... Read more
Published 1 month ago by Justin
Good job
Riceived this product I been used it for long time it's working as it was ment to be working I am pretty happy with it. No complaints so far. Thanks
Published 1 month ago by Joseph
No more flakes...seriously!!
Bought this for my boyfriend who had tried various other dandruff shampoos to get rid of the excessive flakes and nothing worked. Read more
Published 1 month ago by missest
Finally
After trying every dandruff shampoo imaginable (Head and Shoulders, Selsun Blue, Garnier, and more), this is the first and only thing that worked. Read more
Published 2 months ago by kmarie
Performs well
Controls and eliminates dandruff. I don't usually have a dandruff issue, but this winter has been dry. Read more
Published 2 months ago by Ajo
Nizoral Shampoo
Started using this shampoo years ago because of dandruff. It's good at cleaning the scalp but it makes dry scalp and hair worse because it has sulfate in it. Read more
Published 3 months ago by LDz
It's expensive, but it's worth it.
Every once in a while, I will run across a product that quite literally changes my life. This is one of those products. Read more
Published 3 months ago by Bryan J. Kautzman
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