First Sentence:
As with studies involving viral transduction, the delivery of naked nucleic acids can be broken down into several transport steps, including (1) transport of nuclei acids from the site of injection to the liver, (2) exit of nucleic acids out of the liver vessel lumen into contact with hepatocytes, (3) uptake by hepatocytes, (4) entry into the cytoplasm, and (5) entry into the nucleus.
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Key Phrases - Statistically Improbable Phrases (SIPs):
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hydrodynamic delivery, liver gene transfer, naked plasmid transfer, hepatic locus control region, vivo clectroporation, survivin promoter, transposase molecules, lipid vector, cell electropermeabilization, transposon system, persistent gene expression, bovine growth hormone polyadenylation signal, following gene transfer, plasmid injection, mechanical massage, hepatic gene expression, vivo electroporation, hydrodynamic injection, gene transfer agents, intramuscular gene transfer, gene expression cassettes, cancer gene therapy, gene therapy vectors, foreign gene expression, gene therapy studies
Key Phrases - Capitalized Phrases (CAPs):
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Gene Ther, Gene They, Cancer Res, Gene Med, Elsevier Inc, Nature Med, Nucleic Acids Res, Nature Biotechnol, Nature Genet, Cell Biol, Nature Rev, Genes Dev, Cell Mot, Trends Genet, Cancer Inst, Cell Biochem, Expert Opin, Methods Enzymol, Walter Reed, Care Med, Drug Deliv, Lung Cell Mol, Allergy Clin, Cancer Biol, Cell Sci
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