Yes, this album will offend many with a strong religious belief. Not because of it's scientific content. Not even because of its stand on evolution (which some religious people, I understand, accept alongside their faith).
No - this album is offensive to many major religions because it mocks the belief in Angels by likening them to mythical unicorns.
This will be the first TMBG product that I will not be buying in over 20 years of being a fan.