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On Speed: The Many Lives of Amphetamine
 
 
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On Speed: The Many Lives of Amphetamine [Hardcover]

Nicolas Rasmussen (Author)
4.6 out of 5 stars  See all reviews (8 customer reviews)

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Book Description

March 1, 2008 0814776019 978-0814776018 1

Life in the Fast Lane: The author on the CHE

Uppers. Crank. Bennies. Dexies. Greenies. Black Beauties. Purple Hearts. Crystal. Ice. And, of course, Speed. Whatever their street names at the moment, amphetamines have been an insistent force in American life since they were marketed as the original antidepressants in the 1930s. On Speed tells the remarkable story of their rise, their fall, and their surprising resurgence. Along the way, it discusses the influence of pharmaceutical marketing on medicine, the evolving scientific understanding of how the human brain works, the role of drugs in maintaining the social order, and the centrality of pills in American life. Above all, however, this is a highly readable biography of a very popular drug. And it is a riveting story.

Incorporating extensive new research, On Speed describes the ups and downs (fittingly, there are mostly ups) in the history of amphetamines, and their remarkable pervasiveness. For example, at the same time that amphetamines were becoming part of the diet of many GIs in World War II, an amphetamine-abusing counterculture began to flourish among civilians. In the 1950s, psychiatrists and family doctors alike prescribed amphetamines for a wide variety of ailments, from mental disorders to obesity to emotional distress. By the late 1960s, speed had become a fixture in everyday life: up to ten percent of Americans were thought to be using amphetamines at least occasionally.

Although their use was regulated in the 1970s, it didn't take long for amphetamines to make a major comeback, with the discovery of Attention Deficit Disorder and the role that one drug in the amphetamine family—Ritalin—could play in treating it. Today’s most popular diet-assistance drugs differ little from the diet pills of years gone by, still speed at their core. And some of our most popular recreational drugs—including the "mellow" drug, Ecstasy—are also amphetamines. Whether we want to admit it or not, writes Rasmussen, we’re still a nation on speed.


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Editorial Reviews

From Publishers Weekly

Rasmussen, who has taught life sciences and medicine at UCLA and other universities, examines amphetamine as a case study on the place drugs occupy in our culture and our fantasies (of miracle cures and elixirs). The story begins with chemist Gordon Alles's creation of amphetamine in 1929 and continues through its use for weight loss, attention deficit disorders and today's crystal meth craze. Smith, Kline & French (now GlaxoSmithKline) bought the rights for use of the drug and marketed it to treat depression. During WWII, British and American soldiers developed an amphetamine appetite as RAF medics distributed wakey-wakey tablets to bomber crews. At the book's core is an outstanding chapter, Bootleggers, Beatniks and Benzedrine Benders, describing how Benzedrine inhalers, available without a prescription, could be cracked open for a totally new kind of amphetamine experience, exerting a potent influence on music and literature, from Charlie Parker to Jack Kerouac and Allen Ginsberg. Rasmussen has mined magazines, books and newspapers in addition to extensive explorations through U.K. and American archives. He concludes by calling for strong and immediate action to curb the widespread, dangerous use and abuse of amphetamines, emphasizing treatment and harm reduction (like needle exchange) rather than punishment, and better regulation of the pharmaceutical industry. 37 illus. (Mar. 1)
Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved.

Review

" is a significant contribution to the field and should enjoy a broad readership; it will remain in the definitive history of amphetamines in America for years to come."-Bulletin of the History of Medicine,

"Rasmussen has made a significant contribution by mining many heretofore unused archival sources and large ranges of the scientific and medical literature and presenting through analysis and easily understood history of amphetamines and their society to date."-Historian,

"[A] wonderful book that should be required reading for anyone interested in the history of drug use in the United States."-ISIS,

"Nicolas Rasmussen's On Speed: The Many Lives of Amphetamine provides an intriguing and highly readable perspective on the drug and its history... the book is an important piece of scholarship. It is thoroughly researched and engagingly written and should find a wide audience among historians and mental health professionals. On Speed is a groundbreaking study, a fascinating story, and, above all, a timely and thought-provoking call to reflect on the current-day use of psychotropic medication."-Journal of the American Academy of Child & Adolescent Psychiatry,

"Rasmussen blends science, medical history, and social history with fresh archival research. He fills the narrative with telling details and cultural insights. . . . This is a superb book."
-Journal of American History

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Product Details

  • Hardcover: 400 pages
  • Publisher: NYU Press; 1 edition (March 1, 2008)
  • Language: English
  • ISBN-10: 0814776019
  • ISBN-13: 978-0814776018
  • Product Dimensions: 9 x 6 x 1.4 inches
  • Shipping Weight: 1.4 pounds (View shipping rates and policies)
  • Average Customer Review: 4.6 out of 5 stars  See all reviews (8 customer reviews)
  • Amazon Best Sellers Rank: #865,954 in Books (See Top 100 in Books)

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Customer Reviews

Most Helpful Customer Reviews
15 of 15 people found the following review helpful
Format:Hardcover|Amazon Verified Purchase
This thoroughly researched and very well written book is the history of the amphetamine class of drugs that were first created in the early part of the 20th century and are still causing problems for society for today. In addition to the history of the drug, there is an allegorical story running parallel to the drug that is a detailed and scary look at practices in the pharmaceutical industry then and now.

Amphetamine, as a class of drugs, was first discovered by Gordon Alles in 1929 while he was doing research on adrenaline substitutes. Although he was not the first to actually identify the molecule, he was the first to precipitate the salt form and identify it as a potential drug. Eventually he sold the rights to the drug to the Smith Kline French Co. in Philadelphia and the hunt was on to find a use for the new drug, as it was a drug looking for a home.

The story follows the hunt to find a use for the new compound and the efforts by the company to get doctors to experiment with "creative" uses for the compound. The one thing the drug appeared to do well was to make people feel happy and empowered. Other than that, it had little use but the company worked around that problem by getting the military to issue speed to soldiers during World War II as a way of keeping them sharp.

The book follows these uses, as well as the use of the inhaler version for recreational drug use and deals, in detail, with the many times the drug could have been put out to pasture only to be rescued by the company that was making so much money from it.

It is still prescribed today, even given what is known about the addictive properties of the drug. And, of course, illegal drug manufactures discovered numerous ways to make it cheaply from legal products, ensuring that it lives on to today.

While I would not recommend this book as a light read, it is certainly a detailed and fascinating look at a drug the public had no real use for and was sold on anyway. It is well written and very readable for those with an interest in the pharmaceutical industry or for a history of the drug itself.
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8 of 8 people found the following review helpful
Thought provoking December 14, 2008
Format:Hardcover
I am an Australian pediatrician who prescribes stimulants to children. Prior to reading this book I was completely ignorant about the history of these medications and the impact they have had on society. I found the book fascinating and thought provoking. Their use by the military especially during WW2 was most revealing as has been their pervasive impact on popular culture. I would recommend the book to anyone who uses or prescribes these drugs so that they are aware of their potential for abuse as well as their many positive aspects.
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5 of 5 people found the following review helpful
Format:Hardcover
I thoroughly enjoyed this extensively researched, thought-provoking and well-written book. First formulated in the 1930s, speed -- a drug in search of a market - - was initially sold as an antidepressant although results of trials at that time gave little evidence of any effectiveness in that role and substantial evidence of risk. One of the most interesting discussions is on the varied experiences of early testers, who described the drug as anywhere from a confidence-booster (English testers) to a productivity tool (American testers). During World War II, soldiers and airmen of Germany, England, and the U.S. were prescribed speed as an "upper" to keep flight crews awake on long missions and more generally as a morale booster. Interestingly, of the three only Germany stopped using it as its highly addictive and psychotic properties made it dangerous and unreliable. These properties became familiar in the subculture and speed became the drug of choice for beatniks. The postwar years saw an explosion in both prescribed and illicit use of amphetamines with the emergence of happy pills for the middle classes; by the sixties about 1 in 10 Americans were using amphetamines in one form or another. Most shocking to me was the incredible, recent and on-going growth of amphetamines in an entirely new market, namely children and adults with attention deficit disorder.

The book's conclusions are based on actual scientific evidence rather than conventional wisdom about these eras and their cultures. Interesting as the particular story of speed is, it is also used by the author as a proxy for examining the role of drugs, in general, in modern medicine and in society, especially the manner in which drugs are developed and marketed. The book leaves one questioning the reliance on drugs as the treatment of choice for a host of ailments, and the ease with which the latest 'miracle drugs' are widely marketed before the full range of their complications and risks are examined.
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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
benzedrine sulfate, armoured brigade, amphetamine patent, amphetamine epidemic, amphetamine products, pharmaceutical amphetamines, much amphetamine, amphetamine base, amphetamine habit, amphetamine prescriptions, amphetamine pills, amphetamine doses, amphetamine tablets, drug firms, amphetamine use, amphetamine psychosis, amphetamine addiction, amphetamine salts
Key Phrases - Capitalized Phrases (CAPs): (learn more)
United States, Amphetamine's Decline, Benzedrine Inhaler, Attention Deficit, Fast Forward, Benzedrine Benders, New York, The New Sensation, Second World War, West Coast, Los Angeles, Air Force, San Francisco, Eighth Army, Speed Kills, Bomber Command, Boston State, University of Pennsylvania, Joan Vollmer, American Medical Association, Tour de France, University of California, Cold War, North Africa, Henry Dale
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