Customer Reviews

Operators and Promoters: The Story of Molecular Biology and Its Creators

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Hatch Echols was a well-known biologist. He spent years working on a personal history of his field. After his untimely death, his widow completed the manuscript. This book is the result. It is a history of molecular biology from about 1948 to about 1990. By molecular biology he means the attempt to understand biology using the tools of physics and chemistry. It is a superb book, as makes a fine compiment to the OTHER definitive history of molecular biology, Horace Freeland Judson's "Eighth Day of Creation". Judson's 1979(I think) book was a detailed account of three or four episodes in molecular biology, and stopped at 1970. Echols'book gives a much broader overview, focusing on the questions that arose and the people who answered them. The margins are graced by line drawings of the the major actors. The result is a fine account of both the science (briefly) and those who made it. Most of the participants were his friends, and it shows. On the other hand, unlike most books, I am unaware of any animosity or basic unfairness towards any of the participants. Those of you looking for revelations of scandal had best look elsewhere. This is an idyll of discovery. Having studied the subject through textbooks, I enjoyed finding out about the twist and turns, the false starts and blind alleys and leaps in the dark that really lay behind the development of the most exciting science of the last half of the twentieth century. Highly recommended.

This book seems to be languishing in obscurity, and I think Judson's book is out of print. This is deplorable. Another reason to purchase it is because feel Operators and Promoters is a good book to dip into and read a few chapters here and a few there, so you will want to have a copy about the house.

Worth purchasing? Definitely

For all the molecular biology students out there, here is the scoop. If you are working on or planning on working on some aspect of molecular biology and dont know where to start this is the book for you. If you want to become a serious investigator of biochemistry and molecular biology, and dont know what scientists in your specialized field did before you, this is the book for you. Remember, you cannot make an original contribution to science unless you know what has already been contributed!

The book is similar to the higly acclaimed "eigth day of creation" by H.Judson in that it nicely describes the history of what happened in the field of molecular biology in its earliest years and I bet it will be a lot of fun for someone coming into this field. Where the book differs from the other book is when it looks at events that happened much later in history - more recent events. For example, how did the discovery of ribozyme happen? The book goes into the various experiments that were performed in collaboration with other researchers working in related fields. Whats most impressive to this reviewer is that the book cites specific original research articles everytime it makes a bold statement like "this is how the discovery of ribozyme was made" which makes it very easy to get the article and put things in historical perspective (look at the extensive "Notes" section). You will also remember both the experiments that were performed to derive at the original contribution and the scientist. you can take my word, you will not forget either!

Last but not the least, the book has nice pencil illustrations of scientists who made the big contributions and it is essential to relate the scientists with the science. For someone that is not in science, this book will take some effort to read but is definitely not overwhelming. There is a glossary at the end of the book which I bet will be extremely helpful for the non-specialist reader. Overall this book is a gem and will be in my permanent collection.

If you enjoy reading about the history (and the people) of Science, as I do, you will like this book. This is the best book I've read about the early years in Cell and Molecular Biology. This book is an amazing dive into the personalities and classic experiments conducted between 1955-1990 that served as the foundation for the field of Molecular Biology.

The author was a key player in the field at the time and knew many of the people in this book. He spent the last 6 years of his life on this book and to me, it is his love letter to Molecular Biology. His wife, also a key researcher, finished the text and had it published after his death.

I am so glad I bought this book and I often recommend it to undergraduates and to newby science types who want to understand the fundamentals of molecular biology.

This book looks completely brand new even though it was listed as used. Couldn't be happier!