This reference provides a concise overview of the key principles in dose selection and optimization and demonstrates applicability to recent successful new drug applications. Compiling key issues and current research on safety, efficacy, and clinical pharmacology, and PK-PD, this volume critically highlights the multidisciplinary nature of drug development and spans the fields of pharmacokinetics, clinical pharmacology, biostatistics, and experimental medicine.
Dose Optimization In Drug Development
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disease progression modeling, effective threshold concentration, small satellite group, total oral clearance, lib study, biomarkers definitions working group, versus confirming, dose optimization, pathophysiologic cascade, safe starting dose, moderate hepatic impairment, clinical biomarkers, dose selection, biomarker validation, clinical drug development, population pharmacokinetics, new medical products, target patient population, oncology drugs, pediatric subjects, surrogate endpoints, start dose, clinical endpoints, population modeling, allometric scaling Key Phrases - Capitalized Phrases (CAPs): (learn more)
Clin Pharmacol Ther, Clin Pharmacokinet, New York, Annu Rev Pharmacol Toxicol, Clin Oncol, Courtesy of Springer Publications, Pharmacokinet Biopharm, Stat Med, Pharmacokinet Pharmacodyn, End of Week, Nat Rev Drug Discov, Cancer Chemother Pharmacol, Clin Cancer Res, Lilly Research Laboratories, Pharm Res, Pharmacol Exp Ther, Anesth Analg, Cent Biol Eval Res, Arthritis Rheum, Biochem Pharmacol, Clin Endocrinol Metab, Marcel Dekker, New Jersey, Pharm Pharmacol, Ann Rheum Dis New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
disease progression modeling, effective threshold concentration, small satellite group, total oral clearance, lib study, biomarkers definitions working group, versus confirming, dose optimization, pathophysiologic cascade, safe starting dose, moderate hepatic impairment, clinical biomarkers, dose selection, biomarker validation, clinical drug development, population pharmacokinetics, new medical products, target patient population, oncology drugs, pediatric subjects, surrogate endpoints, start dose, clinical endpoints, population modeling, allometric scaling Key Phrases - Capitalized Phrases (CAPs): (learn more)
Clin Pharmacol Ther, Clin Pharmacokinet, New York, Annu Rev Pharmacol Toxicol, Clin Oncol, Courtesy of Springer Publications, Pharmacokinet Biopharm, Stat Med, Pharmacokinet Pharmacodyn, End of Week, Nat Rev Drug Discov, Cancer Chemother Pharmacol, Clin Cancer Res, Lilly Research Laboratories, Pharm Res, Pharmacol Exp Ther, Anesth Analg, Cent Biol Eval Res, Arthritis Rheum, Biochem Pharmacol, Clin Endocrinol Metab, Marcel Dekker, New Jersey, Pharm Pharmacol, Ann Rheum Dis New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
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