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Organolithiums in Enantioselective Synthesis (Topics in Organometallic Chemistry)
 
 
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Organolithiums in Enantioselective Synthesis (Topics in Organometallic Chemistry) [Hardcover]

David M. Hodgson (Editor)

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Book Description

3540001042 978-3540001041 June 4, 2003 1

This volume is the first dedicated to a comprehensive coverage of this rapidly developing transdisciplinary field. It provides a rich source of essential information on synthesizing molecules in an enantioselective manner using organolithiums, and serves as an inspiration for future developments.


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Editorial Reviews

Review

This book is a valuable addition to the Topics in Organo-metallic
Chemistry series that has successfully culled a vast
topic into engaging and focused chapters through skillful
editorship. With minimal redundancy, the short text provides
comprehensive coverage of stereoselective deprotonations using
alkyllithiums in the presence of sparteine; the presentation
balances uninspiring examples with those in which the effectiveness
of the asymmetric depronation strategy is unsur-passed.

Interspersed throughout are complementary methods for
the creation and utilization of organolithiums in myriad reactions
that contribute meaningfully to the usefulness of the text. Clear
chapter headings and subject/author indexes make finding
information easy, and the volume will be a useful addition to
library reference collections.

Brian L. Pagenkopf, University of Texas at Austin

J. Am. Chem. Soc. 2003

To cover this very large subject, which has grown in size over several
decades and continues to develop rapidly, in such a compact form, as in this
volume, was certainly a demanding task, but it has been done successfully.
Through the sensible choice of topic areas and by the arrangement of the
material under different headings, the reader is given easy access to this complex subject.

Bernd Goldfuss
Institut für Organische Chemie
Universität Köln

Angewandte Chemie Int. Ed. 2004, 43, 778-781
www.angewandte.org
2004 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

------

In this monograph, which is the newest addition to the excellent Topics in Organometallic Chemistry series, several authors from eight research groups around the world describe the current state of the art in the area of stereoselectivity control using organolithium reagents.
This book is a fine addition to any collection of synthetic monographs or to a library centering on organometallic reactions. Practitioners of stereoselective synthesis of natural products will likely find it very useful.

Marek Majewski
University of Saskatchewan, Canada

Adv. Synth. Catal. 2005, 347, 719-720
Wiley-VCH


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Inside This Book (learn more)
First Sentence:
Organolithium chemistry pervades organic chemistry, and aspects of organolithium chemistry have been reviewed on several occasions [1-5]. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
diastereoselective lithiation, homoaldol products, dynamic thermodynamic resolution, homoaldol reactions, lithiation adjacent, lithiated epoxides, benzyllithium compounds, enantioselective lithiation, arenechromium tricarbonyl complexes, chiral diether, enantioenriched product, external chiral ligand, electrophile incorporation, arenechromium tricarbonyls, electrophile trapping, intramolecular carbolithiations, asymmetric deprotonation, enantiodetermining step, migrating terminus, asymmetric lithiation, lithiation step, enantioselective generation, double lithiation, electrophilic quench, lithium carbanions
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Tetrahedron Lett, Angew Chem Int Ed Engl, Chem Soc Perkin Trans, Chem Commun, Org Lett, Chem Ber, Organomet Chem, Chem Eur, Felix Marr, Dieter Hoppe, Peter Beak, Chem Rev, Acc Chem Res, New York, Chem Lett, Lithiation Directed, Chem Pharm Bull, Liebigs Ann Chem, Shuichi Nakamura, Enantioselective Addition of Organolithiums, Hely Chim Acta, Markus Brüggemann, Springer-Verlag Berlin Heidelberg, University of Munster, Jonathan Clayden
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