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Orthomolecular Medicine For Everyone: Megavitamin Therapeutics for Families and Physicians

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Orthomolecular Medicine for Everyone
Megavitamin Therapeutics for Families and Physicians
by Abram Hoffer, PhD, MD, FRCP(C) and Andrew Saul, PhD,
2008, Basic Health Publications Inc., CA, 375 pages www.basichealthpub.com

Megavitamin therapeutics? Whazzat? Do vital amines have health-restoring capabilities? In this book, two highly-qualified authors, Abram Hoffer, PhD, MD and Andrew Saul, PhD explain how orthomolecular medicine can help people feel better and live longer. In Part One, Dr. Hoffer (biochemist, physician and psychiatrist-retired) and Dr. Saul (health educator) teach us that: (1) vitamins and minerals are important to human health; (2) nutritional deficiencies can cause health problems; (3) many patients can restore their health by taking supplements; and (4) healing with nutrients only happens if each patient receives optimal doses (much higher than anti-starvation levels). After introducing the concepts of nutritional deficiencies and dependencies and biochemical individuality, the authors outline the healing capabilities of vitamins, starting with B-3, an essential nutrient which has three names: nicotinic acid, niacin and niacinamide. Then Hoffer and Saul explain how orthomolecular doctors treat chronic illnesses and maintain health by prescribing regimens of vitamins A, B, C, D and E with trace minerals and other nutrients.

Part Two details safe, effective and restorative orthomolecular treatments for nine health problems:
(1) gastrointestinal disorders, (2) cardiovascular disease, (3) arthritis, (4) cancer, (5) the aging brain,
(6) psychiatric and behavioral disorders, (7) epilepsy and Huntington's disease,
(8) allergies, infections, toxic reactions, trauma, lupus and multiple sclerosis and (9) skin problems.

Will a poor diet drain our vitality? If we get sick, can nutrients restore our health? Consider mental illness; most psychiatrists quickly label patients, prescribe combinations of meds (antidepressants, antipsychotics and anticonvulsants, etc.) and talk to their psychoses. Non-responsive patients get electric shocks. Early in his career, Dr. Hoffer saw very few recoveries after patients got labels, meds, talks or shocks. He wondered whether psychotic patients might have metabolic disorders rather than neuroleptic deficiencies. Most doctors don't pay any mind if patients eat junk food or self-medicate with alcohol, oblivious to the reality that brain cells need decent food. Certain nutrients are essential. Psychiatrists don't often consider nutrition but Abram Hoffer went to the old school which taught doctors to assess root causes and contributing factors before making a differential diagnosis. As Hoffer evaluated biochemical and nutritional factors underlying psychosis, he discovered that foods and nutrients can affect mental health. Over his long and distinguished career, Dr. Hoffer fine-tuned patients' diets and prescribed regimens of vitamins, trace minerals, amino acids, antioxidants, energy and enzyme cofactors. These treatments helped many of his patients to stop hallucinating, rejoin their communities, work, pay taxes and live well. Impossible, you say?

Initially, Dr. Hoffer networked with a small team of scientists and health professionals who cooperated to research and develop restorative treatments for schizophrenia. Linus Pauling, PhD, read Niacin Therapy, in which Hoffer reported his first patients who recovered taking niacin for acute schizophrenia. Pauling named it "orthomolecular psychiatry" (Science, 1968). Dr. Hoffer explains the restorative dimension of care: "The practice of orthomolecular medicine recognizes that diseases are due to a metabolic fault that is correctable in most patients by good nutrition, including the use of vitamins and mineral supplements."

Megavitamin therapeutics proved safe and effective. Many of Hoffer's acute schizophrenia patients recovered taking optimum doses of a methyl acceptor (B-3, niacin or niacinamide) with an antioxidant (C, ascorbic acid). For more than 50 years, while researching and developing regimens of nutrients to heal psychosis and other mental disorders, Hoffer reported clinical progress and success by improving diets and giving medicinal doses of vitamins B-3, B-6, C, zinc and manganese. Thousands of patients recovered.

Most psychiatrists ignored Hoffer's double-blind placebo-controlled gold-standard research. Without studying his ideas, experiments, data or findings, `modern' psychiatrists dismissed Hoffer's reports of a 75% recovery rate for acute schizophrenia. They did not interview his recovered patients. Believing that thousands of patients and their trusting families could benefit from complementary vitamins and minerals, Abram Hoffer somehow found the time to write more than 30 books and 600 medical journal articles and editorials. For decades, he wrote about the biochemistry of schizophrenia, described the healing capabilities of vitamins and other nutrients, recommended healthy diets and introduced orthomolecular medicine to patients, families, caregivers and health professionals. Hoffer's books include The Chemical Basis of Clinical Psychiatry (1960), Niacin Therapy in Psychiatry (1962), How to Live with Schizophrenia (1966), The Hallucinogens (1967), Smart Nutrients (1980) Orthomolecular Medicine for Physicians (1989), and Adventures in Psychiatry (2005). This 2008 book, clear enough for every reader, is a classic example of Hoffer's thorough research, detailed references, careful observations and thoughtful writing.

While prescribing vitamins for patients, Hoffer took the same daily doses of niacin and ascorbic acid himself (vitamins B-3 and C). How many psychiatrists self-test their treatments? He experienced the niacin flush with two brief side effects: 1. warmth and 2. redness. He had no side attacks or toxic effects while taking vitamins, only side benefits. Abram Hoffer's decades-long personal experiment shows that the right doses of the right nutrients can help a doctor feel better and live longer. Will you live as long as Dr. Hoffer if you take vitamins B-3 and C? Maybe you will; note that Dr. Hoffer wrote this book in his 91st year.

Anyone can read about the decades of research, study the references and consider the regimens which Dr. Abram Hoffer and his colleagues developed, tested, healed thousands of patients with, took themselves and wrote clinical success stories about, since the 1950s. Abram Hoffer and Andrew Saul wrote this informative, insightful, helpful and hopeful book to educate the public how we can restore our health, get proper medical care, adjust our diets and take supplements. Hoffer and Saul encourage us to eat foods that we can metabolize, and take nutritional supplements (vitamins, minerals and amino acids, antioxidants, energy and enzyme co-factors and essential fatty acids). If we suffer from metabolic problems, deficiencies or dependencies, we can ask our health professionals to complement standard treatments with nutritional regimens. If our doctors don't know about restorative care, we can ask for second opinions.

As you read this fascinating book, you will learn how to restore health and live well by eating nutritious foods and asking health professionals to recommend nutritional supplements. Ortho-molecular medicine has helped thousands of patients, for decades. Optimum doses of essential nutrients tested safe and effective. You can help yourself recover, feel better and live longer; then tell your friends and families!

review by Robert Sealey, BSc
author of Finding Care for Depression, Mental Episodes & Brain Disorders
www.searpubl.ca

[Historical note - Decades before Hoffer's time, malnourished and psychotic patients recovered from episodes of pellagra by taking niacin and tryptophan and improving their diets. Ref. Dr. J. Goldberger. Divided doses of vitamin B-3, as niacinamide, were also used to heal arthritis. Ref. Dr. W. Kaufman. In the 1950s, Dr. Hoffer applied his PhD in biochemistry to research schizophrenia, neurotransmitters and metabolic pathways. One evening he had a Eureka moment spotting a common chemical basis, an indole, in hallucinogenic compounds. He wondered if the human brain produces indoles and if so, might those metabolites cause hallucinations or perceptual distortions during episodes of schizophrenia. Dr. Hoffer found indoles by tracking the metabolic pathways of catecholamines, especially when the oxidation of adrenalin shifts irreversibly to adrenochrome (an indole). 1 or 2% of people, schizophrenics, hallucinate that way. Hoffer tested various doses of niacin and ascorbic acid (vit. B-3 and C) and had more Eureka moments as megavitamin therapeutics restored normal brain function in patients with acute schizophrenia.]

I've found Hoffer and Saul's book, "Orthomolecular Medicine for Everyone" to be a fascinating read. As a scientist interested in the topic of nutrition, their analysis of vitamin therapies intrigued me. Especially, as I had already learned much of how conventional medicine (negatively) views megadose vitamins, and nutrition as a solution to disease cures.

The authors rationally point out that we humans are tied very strictly, evolutionarily, to vitamins, minerals, and essential amino acids in the Earth's early environment. Thus, our ancestors' food intake has strongly controlled and influenced our genetic makeup today. Drs. Hoffer and Saul also correctly mention the difference between our ancient ancestors' intake of raw nutritious foods versus today's context of post-industrial food processing with loss of nutrients. A significant amount of food in the market today is sold to make companies profitable for their stockholders rather than to have any value related to nutrition. Indeed, government dietary recommendations are thought to be politically tied to lobbying by major food manufacturers (see Marion Nestle "Food Politics" for more detail). Nutrition suffers much in our day due to decreased nutrients stripped away during the manufacturing process, and owing this the authors make the case that vitamin supplementation is therefore a necessity.

My only concern in the book is that the authors fail to discuss problems with the 1994 U.S. law "Dietary Supplement Health and Education Act", commonly referred to as 'DSHEA'. This law, a result of intense lobbying by supplement companies, led to free market availability of dietary supplements -- the good part. The bad part is there is very little oversight in the quality manufacture of dietary supplements in the United States. Unlike drugs, supplements are not required to be tested and verified for potency listed on the label, or for safety (i.e., no toxins). There has recently more legislation to help improve this situation, so we'll keep our fingers crossed for the future. Plus, more and more companies out there now are quite reputable, but the obligation does still fall mainly on the consumer to figure it out.

Despite this small drawback, I highly recommend this thought-provoking book, especially to those working in medical, research, and nutrition fields. If correct, proper supplementation with vitamins, minerals, and amino acids can offer a way to drastically reduce the number of people afflicted with diseases without the need for expensive and, sometimes, deleterious drug intervention.

ORTHOMOLECULAR MEDICINE FOR EVERYONE is an updated and expanded edition of Dr. Abram Hoffer's long out of print classic, ORTHOMOLECULAR MEDICINE FOR PHYSICIANS. The original book was created as a nutritional reference guide for doctors. This new addition is intended as a reference guide for anyone interested in natural health care, including open-minded physicians.

Dr. Hoffer and Dr. Andrew Saul take us through the research and rationale behind megavitamin therapy and share with us the results of many case studies. This fascinating book provides us with much detailed information, yet remains highly readable. This is a great book! This is an important book!

ORTHOMOLECULAR MEDICINE FOR EVERYONE should be in every home, and on every physician's desk. Buy it, read it, refer to it and tell your friends about it! It's fantastic!

This book is very informative and can give you a clear picture on how different vitamins and minerals work. It also suggested the maximum safty dose you can try, side effect which may occur etc..

Very good book,good guide, highly recommended!

winnie huie
Hong Kong

BRILLIANT! Concise, informative, putting everything into perspective, detailed discussion of deficiency & benefits of supplementing. Must read for anyone who is serious about their health.

This is a must read....if you want to protect your health and age not just gracefully but full of vim and vigor. I have instituted many of his recommendations and I feel great!
I am a science geek so your mileage may vary but it is very readable and do-able for the lay person.

I am enjoying this book at present. There are many good ideas to use to improve one's health. In one place it informs the reader of Vitamin C being used as a general laxative with no bad side effects. It works very well for everyone in this household. It takes more for me than the wife uses. Ten grams is too much. Vitamins really is the way!!! Before you brush-it-off as BS, TRY IT!!

I have alot of vitamin and mineral supplementation books and this one is the best. Ofcourse we all know chemical vitamins made in a factory are dead, i.e. the have no life force energy (they are not the same as the stuff plants make) but I believe there is many positive uses the body can do with them. If you ever wondered if you can take more vitamin supplements or alot more than this is the book you need. This book gives the benefits and side effects with certain dosages. Most vitamin supplements you can well exceed the recommend dosage by huge increments. Have deppression take as much Niacin as it takes too make you better. Stuff like that, this book is great. Love it great reference. I often return to reading passages when I am taking vitamins and I am excited about them, know what I mean??? Love it.

I am very grateful that I purchased this book. I find it very informative with very good resources to reference on the journey to taking better care of myself. I had always believed the food I was eating was depleted and that I need to take supplements. This book really explains in detail the need to exceed the recommended daily allowance to acheive health. I recently shared with my health care provider as well.

This book provides an excellent overview of high dose vitamin therapy. It is very suitable to give to doctors.

The information is very technical in parts and the focus is more on proving the worth and value of nutritional treatments rather than on giving practical advice for those wanting to start their own regime of nutrients.

For that reason, it may be best to read this book together with Dr Atkins' 'Vita-Nutrient Solution' and 'Detoxify or Die' by Dr Sherry Rogers.

This book may be too heavy-going for those with severe diseases such as M.E. as it isn't broken up into many smaller parts as well as many other books. But for those with a real interest in this topic, and healthy enough to read fairly well, this book is an essential addition to your health library.

Highly recommended, especially for doctors.

I just wish I had paid a bit more and gotten a paper copy as I am too ill to read my electronic copy again.

Jodi Bassett, The Hummingbirds' Foundation for M.E.