Osmosis Jones 2001 PG CC

Amazon Instant Video

(162) IMDb 6.2/10
Available in HD
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Frank (Bill Murray "Ocean's Eleven", "Charlie's Angels"), whose body is the "City of Frank" and host to its' inhabitants, falls victim a viral infection.

Bill Murray, Molly Shannon
1 hour 36 minutes

Available in HD on supported devices.

Osmosis Jones

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Product Details

Genres Adventure, Action, Comedy, Kids & Family
Director Bobby Farrelly, Peter Farrelly
Starring Bill Murray, Molly Shannon
Supporting actors David Hyde Pierce, Brandy Norwood, William Shatner, Ron Howard, Kid Rock, Kenny Olson, Jason Krause, Joe C., Stefanie Eulinberg, Jimmie Bones, Uncle Kracker, Jonathan Adams, Carlos Alazraqui, Keith Anthony, Eddie Barth, Sally Ann Brooks, Rodger Bumpass, Michael Carven
Studio Warner Bros.
MPAA rating PG (Parental Guidance Suggested)
Captions and subtitles English Details
Rental rights 24 hour viewing period. Details
Purchase rights Stream instantly and download to 2 locations Details
Format Amazon Instant Video (streaming online video and digital download)

Other Formats

Customer Reviews

Very funny movie.
William King
Osmosis Jones DVD is a great teaching tool to teach young students about the immune system as well as entertaining.
Gwendolyn Worsley
My Kids love this movie!

Most Helpful Customer Reviews

22 of 23 people found the following review helpful By Schtinky VINE VOICE on May 31, 2004
Format: DVD
Osmosis Jones is one of those movies you almost feel like you have to apologize for liking. Well, forget about it, because this is a very funny and downright entertaining movie with no class whatsoever!
The scenes bounce between live acting and full animation, determined by whether we are outside or inside the body of Frank. The casting for this silly and peculiar movie was expertly chosen for both live and voice roles.
Live, we have Bill Murray as Frank, in his most disgusting character since Caddyshack. Chris Elliot plays his brother Bob, and manages to challenge Murray in the "disgusting slob" category. Murray eats a hard boiled egg that landed in monkey doodoo, and thus introduces Thrax into his body, a red-death virus determined to take over Frank and kill him. (voiced by Laurence Fishburne)
Inside of Frank, we go to the animation where Chris Rock is the voice of our hero, a white blood cell named Osmosis Jones. Jones is a detective for the City Of Frank, where William Shatner does the voice for Mayor Phlemming. Jones knows something is wrong, but the Mayor denies any illness could occur in Frank. But just to be safe, he "manually overrides" Frank and has him take a cold pill.
Meet Drix, the huge and snotty cold pill, whose voice is played by David Hyde Pierce (Frazier's brother Niles). Jones and Drix make an unlikely team as they hunt down Thrax and try to stop him from killing Frank.
Nothing is taboo here; they go to the nose and get caught up in the wave of snot when Frank's allergies act up, they travel to The Zit, Frank's hottest new club where Kidney Rock is playing (Kidd Rock), and Jones reminisces about the time he hit the "Panic Button" in Frank's stomach, causing him to vomit all over his daughter Shane's teacher.
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18 of 18 people found the following review helpful By Jamie on December 7, 2004
Format: DVD Verified Purchase
I've been a 5th grade teacher for 5 years and have shown this movie each year as a reward after learning about the human body in science/health. The kids, for the most part, really enjoy it. There is just enough nasty stuff in there to gross them out - which they love! As a teacher, I just love the entire analogy of the story - every little cell in the body is working toward the same goal - keeping Frank alive. The kids like it, and I also enjoy it. There are some moments in there that are more adult humor that the kids don't even catch, so I'm able to get a laugh out of it.
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10 of 10 people found the following review helpful By Ren Culpepper on August 15, 2005
Format: DVD
Osmosis Jones is a really good movie, if a bit... well... disgusting at times.
The plot revolves around a white blood cell named Osmosis Jones (voiced by Chris Rock) who serves as a police officer in the body of a guy named Frank (Bill Murray).
When a dastardly virus named Thrax (voiced by Laurence Fishburne) invades Frank's body, it's up to the immunity force to stop him, and Ozzy is teamed up with a cold tablet named Drixobensomedaphedramine, or Drix for short (voiced by the always-wonderful David Hyde Pierce).
Meanwhile, the pompous blood cell politician in charge of Frank's body, Mayor Phlegmming (voiced by William Shatner), is desperate to win the next election, but he is obviously doing a sub-par job of running Frank's body. His aide (and Ozzy's love interest), Leah, is voiced by Brandy Norwood.

This movie is very amusing in some places, but I had to deduct one star because it is, on occasion, REALLY DARN GROSS. I had to turn my head away from the screen in some places. However, this is by no means a bad movie. I personally consider David Hyde Pierce's portrayal of Drix to be one of the best things in the film (if not the very best), especially when Drix busts a secret mob meeting at a disco and utters the following line, doing some dance steps as he speaks:
"Attention, germs, you are surrounded. Uh-huh, uh-huh. Uh-huh, uh-huh, SURROUNDED!". Trust me, it's worth seeing just for that part.

Overall, Osmosis Jones is definitely worth seeing, and it could also be used to teach an anatomy lesson, because it's very accurate. Just watch out for the gross bits.
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6 of 6 people found the following review helpful By Scott Bright VINE VOICE on November 21, 2001
Format: DVD
Movie Summary: Osmosis Jones is a white blood cell in the body of Frank. He is a cop who defends Frank from invading germs. Frank is a disgusting human being who eats a hard boiled egg from the floor of a monkey's cage and in the process ingests a nasty virus named Thrax. Jones is the only cop who is on to Thrax's evil plan to kill Frank in record time. Jones gets help from an over the counter cold pill named Drix and together they fight to save Frank's life.
My Opinion: The animated portions of the movie were entertaining and fun. The live action portions of the film were gross and not that funny. If it had been 95% animation, this would have been a lot better film. As it is, its audience would be mostly teen and pre-teen boys who are into the gross out humor. Bill Murray's character is disgusting and very hard to like. He doesn't treat his daughter very well. He comes across as very unsympathetic. In the animated portions, all the characters are well done. Chris Rock does an excellent job as Jones. He's funny and you end up rooting for him. David Hyde Pierce is perfect as Drix the cold pill. They make a surprisingly good team. Laurence Fishburne and William Shatner round out the excellent animated cast. If only they could have toned down the live action parts and made Frank more likable. Then we'd probably have a hit on our hands.
DVD Quality: Video: Widescreen anamorphic - 2.35:1 Animation is very crisp and clear. Sound: DD 5.1 The dialog is quiet and the music is loud. Extras: Commentary, Trailers, Behind the Scenes Documentary, Deleted Scenes, Hidden Clip Menus: Average Animated Menus. This is a decent DVD release with a fair amount of extras.
What You Should Do: Rent it if you've got some teen age boys in the house. The animated portion of the story is great, but the live action scenes can get pretty gross.
Related Movies To Check Out: Who Framed Roger Rabbit, Toy Story, Cool World
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