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Ovarian Toxicology (Target Organ Toxicology Series)
 
 
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Ovarian Toxicology (Target Organ Toxicology Series) [Hardcover]

Patricia B. Hoyer (Editor)

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Book Description

April 27, 2004 Target Organ Toxicology Series (Book 19)
In recent years, there has been an alarming increase in environmental by-products that may be harmful to ovarian function. Along with this dangerous situation, the modern trend toward delaying motherhood poses immediate concerns regarding the long-term impact of environmental risks on human fertility. The uncertainty of our reproductive future intensifies the need for a single reference that investigates the chemicals with the potential to jeopardize fertility. The only known text that deals specifically with toxicity in the ovary, Ovarian Toxicology updates our current understanding of the effects of environmental chemicals on ovarian function. This new title in the Target Organ Toxicology Series presents an overview of ovarian physiology, examines the key ovarian target sites, assesses the effects of specific chemicals demonstrated in animal studies, and evaluates related human epidemiological data. Featuring the most complete review available of ovarian metabolism of xenobiotics, chapters also discuss ovarian cancer and modeling and testing for ovarian effects. With its clear handling of data and issues that are crucial to fertility studies, this comprehensive exploration of ovarian toxicology identifies the realistic risks for damage that our environment has the potential to inflict. It will be welcomed by toxicologists and ovarian physiologists, those in the pharmaceutical industries and regulatory agencies, and postgraduate researchers striving to safeguard women's fertility and ensure our reproductive future.

Editorial Reviews

Review

Ovarian Toxicology is probably the first dedicated text to examine the ovary as a toxicological target organ distinct from a treatment encompassing reproductive toxicology … [T]his book is an important work that is highly relevant … and must certainly be considered essential reference matter. … It is highly recommended.
- British Toxicology Society Newsletter

About the Author

Patricia B. Hoyer, PhD, is a Professor in the Department of Physiology at The University of Arizona. Her research is focused on the effects of environmental chemicals on ovarian function. Her professional activities have included memberships in societies, at the National Institute of Health and American Cancer Society study sections, and on editorial boards.

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Inside This Book (learn more)
First Sentence:
The ovary and the testis develop from the same primordial tissue. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
ovarian metabolism, ovotoxic effects, diepoxide metabolite, ovarian aryl hydrocarbon hydroxylase activity, ovarian toxicity, repetitive pseudopregnancies, atrazine exposure, oocyte destruction, membrana propria, ovarian toxicant, follicle loss, immature rat model, getting ovarian cancer, polyovular follicles, cultured granulosa cells, human ovarian cancer cell lines, follicle destruction, human ovarian cancer cells, rat granulosa cells, constant estrus, follicle types, thecal cells, dibromoacetic acid, primordial follicles, antral follicles
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cancer Res, New York, Cancer Inst, United States, Cell Biol, Health Perspect, Environmental Protection Agency, Academic Press, Oxford University Press, North America, San Diego, Steroid Biochem, Cancer Lett, Cell Endocrinol, National Toxicology Program, Technical Report, The Basic Science of Poisons, Biomarkers Prev, Cancer Epidemiol, Comprehensive Toxicology, Drug Metab, Genes Dev, South Korea, The Lancet, Work Environ
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