The first authoritative collection of recent breakthroughs in Parkinson's disease (PD) research, this reference spans key findings on the mechanisms of neurodegeneration and the role of specific genes that may lead to improved therapies for PD. This guide will review the major aspects of the disease including motoric and pathologic features, and autonomic dysfunction, sleep disorders, and neuropsychiatric manifestations, as well as provide an in-depth review of genetic considerations. With contributions by recognized experts on the topic, this source will address the pathogenesis, experimental models, future therapeutic opportunities, and research trends affecting the field.
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parkin disease, parkin mutants, disease genetics study group, parkin mutations, proteasomal inhibition, rotenone infusion, rotenone exposure, parkin gene mutations, parkinsonian diseases, rotenone model, exon rearrangements, parkinson disease gene product, polyubiquitinated proteins, proteasomal dysfunction, neuron integrity, repeat kinase, glial lesions, autosomal recessive parkinsonism, dopamine neuron loss, gene containing mutations, tau haplotype, nigral cell loss, rotenone toxicity, autosomal recessive juvenile parkinsonism, tau gene Key Phrases - Capitalized Phrases (CAPs): (learn more)
Ann Neurol, Biol Chem, Proc Natl Acad Sci, Mov Disord, Exp Neurol, Arch Neurol, Hum Mol Genet, Brain Res, Neurosci Lett, Hum Genet, Biochem Biophys Res Commun, Cell Biol, Acta Neuropathol, Neurol Neurosurg Psychiatry, Neurol Sci, Nat Genet, New York, Nat Med, Neurobiol Aging, Neurobiol Dis, Biochim Biophys Acta, Acta Neurol Scand, Med Genet, Adv Neurol, Pharmacol Exp Ther New!
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parkin disease, parkin mutants, disease genetics study group, parkin mutations, proteasomal inhibition, rotenone infusion, rotenone exposure, parkin gene mutations, parkinsonian diseases, rotenone model, exon rearrangements, parkinson disease gene product, polyubiquitinated proteins, proteasomal dysfunction, neuron integrity, repeat kinase, glial lesions, autosomal recessive parkinsonism, dopamine neuron loss, gene containing mutations, tau haplotype, nigral cell loss, rotenone toxicity, autosomal recessive juvenile parkinsonism, tau gene Key Phrases - Capitalized Phrases (CAPs): (learn more)
Ann Neurol, Biol Chem, Proc Natl Acad Sci, Mov Disord, Exp Neurol, Arch Neurol, Hum Mol Genet, Brain Res, Neurosci Lett, Hum Genet, Biochem Biophys Res Commun, Cell Biol, Acta Neuropathol, Neurol Neurosurg Psychiatry, Neurol Sci, Nat Genet, New York, Nat Med, Neurobiol Aging, Neurobiol Dis, Biochim Biophys Acta, Acta Neurol Scand, Med Genet, Adv Neurol, Pharmacol Exp Ther New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
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