NEW Patent CD for Tramadol multiple unit formulations

by BrainDex LLC

Product Features

• Patent Search on CD containing over 50 related patents in High Resolution PDF format
• CD of information on Tramadol multiple unit formulations
• Includes drawings, schematics, diagrams and other illustrations of patented technology
• Excellent for researchers, hobbyists, students, teachers, librarians, scientists & engineers
• Braindex has served thousands of satisfied customers in over 25 countries worldwide

Product Description

Following is a sample of the information contained on this CD: FIELD OF THE INVENTION The invention relates to oral, multiple unit formulations of delayed-release pellets which contain a pharmacologically active component coated by at least one pharmaceutically acceptable, release-delaying substance, and to a process for their preparation. BACKGROUND Single unit controlled release tablet dosage forms of drugs have known disadvantages compared to the more desirable multiple unit dosage forms. In single dosage matrix tablets the active ingredient is dispersed as a solid in an inert, release delaying matrix. The embedding matrixing material that slows the release of the drug is usually an insoluble plastic (e.g. methyl acrylate-methacrylate, polyvinyl chloride, or polyethylene), a hydrophilic polymer (e.g. methylcellulose, hydroxypropylmethylcellulose, or sodium carboxyl methylcellulose), or fatty compounds (e.g. various waxes, such as carnauba wax, or glyceryl stearate). Such tablets pass undisintegrated through the gastrointestinal tract, and become ever smaller due to breakdown (erosion tablets), or wherein the active compound is released only in the intestine (enteric-coated tablets), in either case depleting the surface inward through the matrix by dissolution or diffusion through the matrix to the external solution. Multiple unit dosage forms are usually contained within a rapid dissolving capsule, or are compressed into a tablet, and soon after ingestion upon its dissolution fall apart into the multiple units, such as pellets. The sub-units or pellets have the desired slow release properties of the dosage form. In contrast to the matrixed formulations, the multiple unit pellets are each surrounded by a polymeric delay release film coating that provides the controlled, slowed release of the active ingredient from within the pellet. These coated dosage forms are generally referred to as reservoir devices when diffusion phenomena occur

Product Details

• Shipping Weight: 3.5 ounces
• ASIN: B002B4FRVU