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1. Neurons undergo a variety of responses to cellular injury a. Manifestations of axonal damage 1) Distal Wallerian degeneration of axon & myelin 2) Proximal central chromatolysis cell body swelling, nucleus & Nissl body (rough endoplasmic reticulum) pushed to periphery 3) Prolonged axon injury retrograde cell body decay b. If synaptic input is lost, get transsynaptic degeneration c. Cell bodies injured directly by anoxia, glutamate excitotoxicity, apoptosis, metabolic storage diseases (Tay-Sachs, etc.)
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corrected bicarbonate, keratin pearls, gap acidosis, nephritic syndrome, recessive defect, bitemporal hemianopsia, hypersegmented neutrophils, most common tumor, psammoma bodies, noncaseating granulomas
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African Americans, Fence Creek Publishing
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