This book examines the danger that exposure of individuals to carcinogenic agents may cause cancers in their offspring, either by a transplacental effect from mother to fetus or by a genetic effect on the germ cells before conception. Over thirty international experts review the most current research in the field, discussing exposure analysis in animals, metabolism of carcinogens, the role of oncogenes, multigeneration animal experiments and human epidemiological studies. Agents considered include polycyclic aromatic hydrocarbons, drugs such as diethylstilbestrol, viruses and radiation, and the atomic bombings of Hiroshima and Nagasaki.
