Pharmacogenomics in Drug Discovery and Development (Methods in Molecular Biology) [Hardcover]

Qing Yan (Editor)

Book Description

ISBN-10: 1588298876 | ISBN-13: 978-1588298874 | Publication Date: March 19, 2008 | Edition: 1

The field of pharmacogenomics arose to develop personalized medicine, or medicine that deals with the complexity of the human body. In this book, leading experts present methodical, state-of-the-art contributions covering topics from individual molecules to systemic diseases, examining both fundamental concepts and advanced technologies. The volume begins by exploring cutting-edge technologies used to pursue systems-based pharmacogenomics, followed by extensive chapters on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases. This book is ideal for scientists striving to transform disease treatment into disease prevention.

Editorial Reviews

Review

From the reviews: "This volume in the Methods in Molecular Biology series covers pharmacogenomics in drug discovery. … The book is intended for scientists in academic, industrial, and health care settings who are striving to transform disease treatment into disease prevention. … The advanced technologies are presented in a very detail manner, even including step-by-step protocols. … By covering topics from individual molecules to systemic diseases … this book provides an overview of current knowledge on the use of pharmacogenomics in therapeutics of disease." (Xiaobo Zhong, Doody’s Review Service, July, 2008)

From the Back Cover

Since each human is genetically distinctive, responding differently to disease-causing factors as well as drugs, the field pharmacogenomics arose to develop personalized medicine, or medicine that deals with the complexity of the human body.  In Pharmacogenomics in Drug Discovery and Development, leading experts present methodical, state-of-the-art contributions covering topics from individual molecules to systemic diseases, examining both fundamental concepts and advanced technologies.  Divided into three sections, the volume begins by exploring cutting-edge technologies used to pursue systems-based pharmacogenomics, followed by extensive chapters on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases. Although not in standard Methods in Molecular Biology™ series format, the book retains the practicality and usefulness of the highly successful series. Comprehensive and up-to-date, Pharmacogenomics in Drug Discovery and Development is an ideal volume for scientists striving to transform disease treatment into disease prevention.

Product Details

• Hardcover: 500 pages
• Publisher: Humana Press; 1 edition (March 19, 2008)
• Language: English
• ISBN-10: 1588298876
• ISBN-13: 978-1588298874
• Product Dimensions: 9.3 x 6.3 x 1.1 inches
• Shipping Weight: 2.1 pounds (View shipping rates and policies)
• Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
• Amazon Best Sellers Rank: #1,330,273 in Books (See Top 100 in Books)

Customer Reviews

Most Helpful Customer Reviews

2 of 2 people found the following review helpful:

5.0 out of 5 stars A timely book on personalized medicine for all levels, June 17, 2008

By 

Personalized Medicine - See all my reviews

This review is from: Pharmacogenomics in Drug Discovery and Development (Methods in Molecular Biology) (Hardcover)

From fundamental concepts to advanced technologies in pharmacogenomics, this comprehensive book is useful for those interested in personalized medicine at all levels. The book discusses pharmacogenomics in three parts: technologies, molecules, and diseases and treatments. The first part of the book introduces cutting-edge technologies in pharmacogenomics, including bioinformatics, microarray, and association studies. The second part of the book discusses biomarkers and molecules including membrane transporters, receptors, and enzymes. This part includes three chapters on pharmacogenomics of G protein-coupled receptors (GPCR), providing a complete discussion on GPCR genetic variations, their relationships with diseases, and their potential uses as drug targets. The third part of this book focuses on diseases and treatments including psychiatric disorders, cardiovascular diseases, cancer, Alzheimer's disease, gastrointestinal disorders such as inflammatory bowel disease and irritable bowel syndrome, autoimmune diseases such as asthma and rheumatoid arthritis, and infectious diseases and vaccines.