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by Rob Phillips
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by John A. Adam
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by Ahmed Zewail
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by Timothy Gowers
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by Daniel A. Beard
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This book brings about the confluence of various concepts and tools to address significant problems of our time in physical biology and adjacent disciplines. The volume is structured to provide a broad perspective on current state-of-the-art methods and concepts at the heart of chemical and biological behavior, covering the topics of visualization; theory and computation for complexity; macromolecular function, protein folding, and protein misfolding; molecular recognition; and systems integration from cells to consciousness. The scope of tools is wide-ranging, spanning imaging, crystallography, microfluidics, single-molecule spectroscopy, and synthetic probe targeting, either molecular or by metallic particles. The perspectives are from the point of view of world leaders in physics, chemistry, and biology; and they define potential new frontiers at the interface of these disciplines, including physical, systems, and synthetic biology.
Contents: The Preoccupations of 21st-Century Biology (D Baltimore); Physical Biology: 4D Visualization of Complexity (A H Zewail); The Challenge of Quasi-Regular Structures in Biology (R D Kornberg); The Future of Biological X-ray Analysis (D C Rees); Biology by the Numbers (R Phillips); The Neurobiology of Consciousness (C Koch & F Mormann); Precision Measurements in Biology (S R Quake); Symmetry Breaking, Delocalization and Dynamics in Electron Transfer Systems (N S Hush); and other papers.
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