Physiology and Pathophysiology of Leukocyte Adhesion [Hardcover]

D. Neil Granger (Editor), Geert W. Schmid-Sch�1/2nbein (Editor)

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Book Description

Publication Date: January 5, 1995 | ISBN-10: 0195081021 | ISBN-13: 978-0195081022 | Edition: 1

Leukocytes play an integral role in the pathogenesis of different inflammatory disorders. Recent results indicate that leukocytes are also involved in conditions that had not formerly been associated with a cytotoxic effect by leukocytes. In 27 chapters by leading investigators, this book reviews recent research on leukocyte adhesion and microvascular kinetics. Detailed descriptions of adhesive glycoproteins expressed on the surface of leukocytes and endothelial cells are given together with summaries of the current state of leukocyte rheology, kinetics and entrapment in microvessels. Since leukocytes reach all organs, the mechanisms described in this volume may apply to a wide range of cardiovascular disorders. A variety of important inflammatory and circulatory disorders are discussed including cerebral and coronary ischemia, shock, atherogenesis, chronic venous insufficiency, gastric ulcer and diabetic retinopathy. New concepts about the etiology of cardiovascular complications are presented, with emphasis on molecular, cellular, and microvascular mechanisms. The current state of endogenous anti-adhesive and pro-adhesive mediators is summarized, including interventions against leukocyte activation and adhesion.

#outer_postBodyPS { display: none; } #psGradient { display: none; } #psPlaceHolder { display: none; } #psExpand { display: none; } Leukocytes play an integral role in the pathogenesis of different inflammatory disorders. Recent results indicate that leukocytes are also involved in conditions that had not formerly been associated with a cytotoxic effect by leukocytes. In 27 chapters by leading investigators, this book reviews recent research on leukocyte adhesion and microvascular kinetics. Detailed descriptions of adhesive glycoproteins expressed on the surface of leukocytes and endothelial cells are given together with summaries of the current state of leukocyte rheology, kinetics and entrapment in microvessels. Since leukocytes reach all organs, the mechanisms described in this volume may apply to a wide range of cardiovascular disorders. A variety of important inflammatory and circulatory disorders are discussed including cerebral and coronary ischemia, shock, atherogenesis, chronic venous insufficiency, gastric ulcer and diabetic retinopathy. New concepts about the etiology of cardiovascular complications are presented, with emphasis on molecular, cellular, and microvascular mechanisms. The current state of endogenous anti-adhesive and pro-adhesive mediators is summarized, including interventions against leukocyte activation and adhesion.

Editorial Reviews

About the Author

D. Neil Granger is at Louisiana State University Medical Center. Geert W. Schmid-Schonbein is at University of California, San Diego.

Product Details

Hardcover: 520 pages
Publisher: Oxford University Press, USA; 1 edition (January 5, 1995)
Language: English
ISBN-10: 0195081021
ISBN-13: 978-0195081022
Product Dimensions: 9.3 x 6.2 x 1.2 inches
Shipping Weight: 2.2 pounds

Average Customer Review: 5.0 out of 5 stars See all reviews (1 customer review)

Amazon Best Sellers Rank: #5,387,353 in Books (See Top 100 in Books)

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5.0 out of 5 stars Used medical text., September 19, 2011

Bop Berrigan (Englewood, FL) - See all my reviews

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This review is from: Physiology and Pathophysiology of Leukocyte Adhesion (Hardcover)

A new medical text on this subject would cost ~$100. I paid $5.00 for a used text in near perfect condition. Need I say more????

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