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Population Genetics, Molecular Evolution, and the Neutral Theory: Selected Papers
 
 
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Population Genetics, Molecular Evolution, and the Neutral Theory: Selected Papers [Paperback]

Motoo Kimura (Author), Naoyuki Takahata (Editor)
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Book Description

0226435636 978-0226435633 January 1, 1995 1
One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change.

Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift.

Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.

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Product Details

  • Paperback: 704 pages
  • Publisher: University Of Chicago Press; 1 edition (January 1, 1995)
  • Language: English
  • ISBN-10: 0226435636
  • ISBN-13: 978-0226435633
  • Product Dimensions: 9.4 x 6.6 x 1.5 inches
  • Shipping Weight: 2.6 pounds (View shipping rates and policies)
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #1,973,939 in Books (See Top 100 in Books)

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9 of 9 people found the following review helpful:
5.0 out of 5 stars A great collection., November 30, 1999
My only regret is that I had entered the field of evolutionary biology too late to have met Kimura. Although the neutral theory has perhaps had the most ranging effect, I would rather place his work with diffusion models as his most important contribution. This collection puts together the beautiful diffusion papers written by Kimura on the subjects of fixation probability, quantitative genetics and more -- including the hard-to-get work in Applied Probability! One of the most valued books in my collection.
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Inside This Book (learn more)
First Sentence:
In the early days when Kimura started to work at the National Institute of Genetics, he presented his preliminary results in the annual report of the Institute. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
chromosomal variance, minimum genetic load, circular pair mating, quasi linkage equilibrium, average time until fixation, horotelic evolution, unfixed classes, evolutionary base substitutions, rare variant alleles, amino acid site per year, advantageous mutant gene, circular mating, extensive neutral evolution, neutral mutant gene, subterminal classes, effective population number, mutation rate per gamete, random gene frequency drift, synonymous component, individual mutant gene, viability polygenes, substitutional load, possible allelic states, overdominant loci, associative overdominance
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Monte Carlo, University of Wisconsin, Clarendon Press, Sewall Wright, Academic Press, Cambridge University Press, Proc Natl Acad Sci, Cold Spring Harbor Symp, Princeton Univ, Japan Contributed, Human Genet, Maynard Smith, Mol Evol, Columbia Univ, Genetics Kimura, Genet Res, John Wiley, Department of Genetics, Japan Scientific Societies Press, National Biomedical Research Foundation, National Institutes of Health, Cambridge Phil, Mathematics Research Center, The Theory of Gene Frequencies
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