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Post-translational Modifications of Proteins
 
 
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Post-translational Modifications of Proteins [Hardcover]

John J. Harding (Author), M. James C. Crabbe (Author)

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Book Description

December 13, 1991 084934171X 978-0849341717 1
Post-Translational Modifications of Proteins discusses several important topics of interest to researchers and students in protein chemistry and biochemistry, including the occurrence and function of hydroxylated residues and the three enzymes required for their formation; the damaging effects of reactions between sugars and proteins; ADP-riboosylation of proteins outside the nucleus; and Monod, Wyman, and Changeux's concerted model for allosteric control of enzyme activity exemplified by studies on glycogen phosphorylase. The application of Fast Atom Bombardment Mass Spectometry (FAB-MS) to studies on the structure and biosynthesis of various oligosaccharide moieties in protein is examined, and the understanding of the structural diversity and function of glycoprotein oligosaccharides is discussed in this volume.

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Inside This Book (learn more)
First Sentence:
4-Hydroxyproline, 3-hydroxyproline and hydroxylysine (Figure 1) are found in animals almost exclusively in collagens and a few other extracellular proteins with collagen-like amino acid sequences. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
vertebrate prolyl, phosphodolichol pathway, plant prolyl, animal prolyl, chick embryo prolyl, same collagen type, coumalic acid, tower helices, glycogen storage site, cofactor phosphate, protocollagen proline hydroxylase, human prolyl, lysyl hydroxylase, allosteric effector site, lysine hydroxylation, nonenzymatic glycosylation, cuticle collagen, inhibitor site, prolyl hydroxylase activity, enzyme derivative, protein disulfide isomerase, glycosylation endproducts, substrate phosphate, hydroxylase reaction, vertebrate enzyme
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Biol Chem, Acad Sci, Academic Press, Res Commun, Trends Biochem, Biochem Biophys, Biophys Res, Proc Natl, Annu Rev, Biochim Biophys, Arch Biochem, Cell Biol, Biophys Acta, University of Oxford, Glycans Linked, Infect Immun, Nail Acad, Natl Acad, Anna Rev, Fast Atom Bombardment Mass Spectrometry, Methods Enzymol, Plenum Press, Rev Biochem, Van Halbeek
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