This extensively up-dated and expanded edition provides the busy clinician with an essential overview of the latest developments in human cancer genetics - an area that has made significant advances since publication of the first edition. The opening section presents the principles of cancer genetics and introduces the basic concepts and mechanisms of tumorigenesis and inherited predisposition to cancer. The second part of the book provides information, on a systems basis, on the incidence, significance and management of predisposition to individual cancers. The final section then deals with specific inherited cancer syndromes, giving practical guidance on clinical investigation, screening and management of affected patients and relatives at risk. Up-to-date details of the genetic mapping of inherited cancer syndromes and the molecular genetic changes in individual cancers are also provided. Finally, an appendix provides a helpful revision guide to the fundamental principles of genetics. This practical and clear account will benefit clinicians and research workers in oncology, genetics, surgery and general medicine.
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."..a good quick reference on the genetics of human cancers. Its small format and straightforward style make it practical and easy-to-use." Stephen P. Tomasovic, The Cancer Bulletin
Book Description
This extensively up-dated and expanded edition provides the busy clinician with an essential overview of the latest developments in human cancer genetics - an area that has seen significant advances since publication of the first edition. It will be of value to clinicians and researchers in oncology, genetics, surgery and general medicine, and to genetic counsellors.
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Inside This Book
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First Sentence:
Demand for cancer risk assessment based upon the estimation of the genetic component of cancer risk to a given individual is increasing rapidly. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
familial meningioma, syndromic features, cerebellar haemangioblastoma, dermatological features, lodgkin disease, bilateral tumours, granulosa cell tumours, sporadic tumours, melanoma families, glomus tumours, genetics centre, germline mutations, yearly colonoscopy, founder mutations, embryonal tumours, naevus syndrome, optic glioma, mutation carriers, vestibular schwannoma, polyps occur Key Phrases - Capitalized Phrases (CAPs): (learn more)
Ashkenazi Jewish, Peutz Jeghers, North America, Ashkenazi Jews, Breast Cancer Linkage Consortium, Amsterdam Criteria, Tuberose Sclerosis Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Demand for cancer risk assessment based upon the estimation of the genetic component of cancer risk to a given individual is increasing rapidly. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
familial meningioma, syndromic features, cerebellar haemangioblastoma, dermatological features, lodgkin disease, bilateral tumours, granulosa cell tumours, sporadic tumours, melanoma families, glomus tumours, genetics centre, germline mutations, yearly colonoscopy, founder mutations, embryonal tumours, naevus syndrome, optic glioma, mutation carriers, vestibular schwannoma, polyps occur Key Phrases - Capitalized Phrases (CAPs): (learn more)
Ashkenazi Jewish, Peutz Jeghers, North America, Ashkenazi Jews, Breast Cancer Linkage Consortium, Amsterdam Criteria, Tuberose Sclerosis Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
14
books
cite this book:
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- Inherited Susceptibility to Cancer: Clinical, Predictive and Ethical Perspectives (Cambridge Cancer Series) by William D. Foulkes on 4 pages
- Counseling About Cancer: Strategies for Genetic Counseling by Katherine Schneider on page 117, and page 127
- Bowel Cancer by Barbara Borwell on page 192
- Molecular Biology of Cancer (Advanced Texts) by Fiona Macdonald on page 171
- Genetics for Surgeons by Patrick J. Morrison in Back Matter
See all 14 books citing this book
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