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Practical Preimplantation Genetic Diagnosis
 
 
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Practical Preimplantation Genetic Diagnosis [Hardcover]

Yury Verlinsky (Author), Anver Kuliev (Author)

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Book Description

1852339209 978-1852339203 October 21, 2005 1st Edition.
From the leaders in the field comes this new and completely up-to-date practical manual of the technique of preimplantation genetic diagnosis. Vital for all practitioners within the field of fertility and reproductive medicine and medical genetics, this will be the leading reference resource for anyone with a practical interest in this most controversial of areas.

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Editorial Reviews

Review

From the reviews of the first edition: "This book is designed to offer a clear guide to those clinicians and scientists who are interested in preimplantation genetic diagnosis. It is written by two pioneers and practitioners within the field and takes the reader through the practical, scientific and more briefly, the ethical, social and legal aspects of preimplantation genetic diagnosis and its broader applications. … The book is a pictorical pleasure with informative diagrams, photographs and tables where necessary." (Alison Lashwood and Pam Renwick, Human Genetics, Vol. 120, 2006)

From the Back Cover

Although treatment is the major goal in the control of genetic disease, this is not yet a reality for most of inherited conditions. Even with the dramatic advancement in field of gene therapy, there are unfortunately not enough success stories to allow us to predict its impact in the near future. Preimplantation genetic diagnosis (PGD) offers the answer to the control of these inherited conditions by predicting reproductive outcome. It is no longer an experimental procedure, having become an integral part of genetic practices and assisted reproduction technology. This practical book is a vital new addition to the literature for fertility clinicians providing a comprehensive description of available experience, indications, methods and clinical outcomes. The authors of this book, from the Reproductive Genetics Institute in Chicago, USA, are among the leaders in this break-through field. Within this book, they instruct readers of the core features of the practice of PGD, while also providing incredibly detailed instructions of the genetics of a wide variety of common and not so common disorders that can be identified with the technique. This thorough and illuminating coverage ensures that this is the definitive reference book for those fertility specialists wishing to set up or already run a PGD clinic.

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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
preimplantation genetics, affected father, linked marker analysis, traditional prenatal diagnosis, chromatid errors, blastomere analysis, aneuploidy testing, unbalanced embryos, maternal recombination, sperm duplication, extra chromatid, normal maternal allele, clinical cycles, diagnosis for single gene disorders, blastomere biopsy, maternal mutation, unaffected embryos, polar body analysis, two linked markers, euploid embryos, mutant oocytes, derived translocations, plantation diagnosis, allele drop, polar body removal
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Assist Reprod Genet, Hum Genet, Hum Reprod, Fertil Steril, Prenat Diagn, International Working Group, Nat Genet, Annealing Gene, Fifth International Symposium, Embryos Pregnancy Birth, Preimlantation Genetics, Med Genet, Ashkenazi Jews, United States, Downers Grove, New York, Hum Mol Genet, Mol Cell Endocrinol, International Conference, Gene Disease Number Inheritance Name, Abstracts of International Seminar, Outside Intron, Proc Natl Acad Sci, Istanbul Memorial Hospital, North America
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