Designed for easy use by both new and experienced protein crystallographers, this much-needed book is for anyone interested in solving protein structures by the method of crystallography. It contains many examples ofactual experiments and data, including electron density maps. Computer methods and computer code samples are presented. Practical Protein Crystallography is loaded with new information on area detectors, synchrotron radiation techniques, and the latest computer methods, and features the XtalView software system. Graduate students and teachers in physical biochemistry and pharmaceutical researchers will find this text a timely and convenient aid.
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Book Description
Editorial Reviews
Review
The author has done and excellent job in presenting his personal experience in this field. He writes in a casual style which make reading easy.
As a manual, the book is highly useful and should be on the shelf in every protein crystallography laboratory
--STRUCTURE
As a manual, the book is highly useful and should be on the shelf in every protein crystallography laboratory
--STRUCTURE
From the Back Cover
Designed for easy use by both beginning and experienced protein crystallographers, the Second Edition of Practical Protein Crystallography is an essential handbook for any scientist interested in solving a protein structure. The book includes examples of actual experiments and data, electron density maps, and computer methods. This Second Edition has been expanded to cover CCP4, SHELX, cryocrystallography, MAD phasing, mmCIF, and automated fitting.
Key Features
* In-depth coverage of every aspect of crystallography
* Coverage of the small details that can make or break projects
* Strongly application-oriented
* Exceptionally well illustrated
* Simple and easy-to-follow robust methods
* Tutorials with actual data available on the Web
* Useful for a broad spectrum of scientists --This text refers to an alternate Hardcover edition.
Key Features
* In-depth coverage of every aspect of crystallography
* Coverage of the small details that can make or break projects
* Strongly application-oriented
* Exceptionally well illustrated
* Simple and easy-to-follow robust methods
* Tutorials with actual data available on the Web
* Useful for a broad spectrum of scientists --This text refers to an alternate Hardcover edition.
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Most Helpful Customer Reviews
5 of 5 people found the following review helpful:
5.0 out of 5 stars
A book for crystallography newbies!,
This review is from: Practical Protein Crystallography, Second Edition (Hardcover)
I'd read the first book, back in my undergrad days and resorted to another to get the overall jist of things for basic understanding. But now that I'm actually a "practicing" crystallographer, I find this book indispensable. McRee explains with both detail and DIRECTION such that not only is the context understandable, but it is USABLE...hence the title of the book. All I could wish for were problems, like solving difference Pattersons and the likes...
4 of 4 people found the following review helpful:
5.0 out of 5 stars
I wish there were more like it!,
By J.Hobbs (SLAC, Stanford, CA USA) - See all my reviews
This review is from: Practical Protein Crystallography (Hardcover)
I discovered this book in my final year of my PhD, and I am so glad I did. It was indispensible to me and a great revision guide in the time leading upto my viva. I am now doing a post doc in protein crystallography and still use it and recommend it to graduate students and undergrads. I just wish that there were more books similar to this one, but going through other protein crystallography programs and showing how to solve structures. This book is mainly for XtalView and SHELX structure solutions, can you write another one on O and CNS & REFMAC structure solutions! Totally worth every penny and have had to buy another copy as the one I had originally has worn away!
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Inside This Book
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First Sentence:
A protein sample must be properly prepared before it can be used in a crystal growth experiment. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
electron density histograms, transfer dewar, acentric reflections, precession photo, cold nitrogen stream, rotation photography, focus residue, artificial mother liquor, riding hydrogens, omit map, phase bias, phasing power, molecular replacement solution, protein refinement, phasing information, canvas menu, reflection file, crystal trials, dispersive difference, anomalous scatterer, series termination errors, vitreous water, photoactive yellow protein, cold gas stream, phase file Key Phrases - Capitalized Phrases (CAPs): (learn more)
San Diego, Academic Press, Auto Fit, Acta Crystallogr, International Tables, Scripps Research Institute, Insert Res, Load Map, Load Sequence, New York, Refine Region, Run Command, Average Filter, Chapel Hill, Hampton Research, Input Argument, Kevin Cowtan, Load Model, Sigma Cut, Split Residue New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
A protein sample must be properly prepared before it can be used in a crystal growth experiment. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
electron density histograms, transfer dewar, acentric reflections, precession photo, cold nitrogen stream, rotation photography, focus residue, artificial mother liquor, riding hydrogens, omit map, phase bias, phasing power, molecular replacement solution, protein refinement, phasing information, canvas menu, reflection file, crystal trials, dispersive difference, anomalous scatterer, series termination errors, vitreous water, photoactive yellow protein, cold gas stream, phase file Key Phrases - Capitalized Phrases (CAPs): (learn more)
San Diego, Academic Press, Auto Fit, Acta Crystallogr, International Tables, Scripps Research Institute, Insert Res, Load Map, Load Sequence, New York, Refine Region, Run Command, Average Filter, Chapel Hill, Hampton Research, Input Argument, Kevin Cowtan, Load Model, Sigma Cut, Split Residue New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
Citations (learn more)
This book cites 7
books:
See all 7 books this book cites
19
books
cite this book:
See all 19 books citing this book
- Macromolecular Crystallography with Synchrotron Radiation by John R. Helliwell on page 36, page 84, and page 185
- Protein Crystallography (Molecular Biology Series) by T. L. Blundell in Front Matter, and page 34
- Structure Determination by X-Ray Crystallography by Mark F.C. Ladd in Front Matter
- Principles of Protein X-ray Crystallography (Springer Advanced Texts in Chemistry) by Jan Drenth in Front Matter
- Computer Graphics Using Open GL (2nd Edition) by Francis S. Hill on page 69
See all 7 books this book cites
- Structure Determination by X-Ray Crystallography by Mark F.C. Ladd on page 625, and page 678
- Crystal Structure Determination by Werner Massa in Back Matter
- Protein Methods by Daniel M. Bollag on page 388
- From Semiconductors to Proteins: Beyond the Average Structure (Fundamental Materials Research) by S.J.L. Billinge in Back Matter
- Protein Structure: Determination, Analysis, and Applications for Drug Discovery by Daniel Chasman on page 90
See all 19 books citing this book
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