Preclinical and Clinical Modulation of Anticancer Drugs focuses on the theoretical and practical approaches to designing and enacting modulation principles. Each class of anticancer drug and the different types of modulators used within each drug class are discussed within individual chapters. The molecular and biochemical rationale for the use of specific modulators is discussed in detail, and preclinical and clinical implications of the data are integrated into each chapter. Mechanisms of drug resistance and the reasons behind circumventing the resistant phenotype are covered. The book will interest cancer chemotherapists, pharmacologists, oncologists, biochemists, and experimental therapeutics researchers, in addition to students studying the principles of drug discovery and protocol design.
FREE Two-Day Shipping for students on millions of items. Learn more |
Book Description
Product Details
Would you like to update product info or give feedback on images?
|
More About the Author
Discover books, learn about writers, read author blogs, and more.
Customer Reviews
|
There are no customer reviews yet.
|
|||
|
Video reviews
|
Inside This Book
(learn more)
First Sentence:
One of the fundamental approaches of conventional cancer chemotherapy has been to focus attention on mechanisms by which the therapeutic index of standard single agents may be improved. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
acid sulfoximines, human colon adenocarcinoma xenografts, rat brain tumor cells, photolabeling agents, thymidylate synthase inhibition, folate species, nitrosourea cytotoxicity, vinca alkaloid resistance, cont inf, sequential methotrexate, mdrl expression, advanced colorectal carcinoma, reduced folate pools, reversing resistance, clinical modulation, colon adenocarcinoma cells, alkyltransferase activity, brequinar sodium, methotrexate cytotoxicity, neoplastic cell lines, vincristine resistance, therapeutic selectivity, advanced colorectal cancer, modulation protocols, mouse leukemia cells Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cancer Res, Cancer Treat, Cancer Chemother, New York, Cancer Clin, Cancer Commun, Academic Press, Cancer Lett, Cell Pharmacol, Cell Physiol, Nucleic Acids Res, Cancer Invest, Cell Biol, Cell Res, New Drugs, Pharmacology Experimental Therapeutics, Plenum Publishing, Radiation Research, Clinical Trials of Sequential, Drug Metab, Inhibition of Polyamine Metabolism, Trends Biochem New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
One of the fundamental approaches of conventional cancer chemotherapy has been to focus attention on mechanisms by which the therapeutic index of standard single agents may be improved. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
acid sulfoximines, human colon adenocarcinoma xenografts, rat brain tumor cells, photolabeling agents, thymidylate synthase inhibition, folate species, nitrosourea cytotoxicity, vinca alkaloid resistance, cont inf, sequential methotrexate, mdrl expression, advanced colorectal carcinoma, reduced folate pools, reversing resistance, clinical modulation, colon adenocarcinoma cells, alkyltransferase activity, brequinar sodium, methotrexate cytotoxicity, neoplastic cell lines, vincristine resistance, therapeutic selectivity, advanced colorectal cancer, modulation protocols, mouse leukemia cells Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cancer Res, Cancer Treat, Cancer Chemother, New York, Cancer Clin, Cancer Commun, Academic Press, Cancer Lett, Cell Pharmacol, Cell Physiol, Nucleic Acids Res, Cancer Invest, Cell Biol, Cell Res, New Drugs, Pharmacology Experimental Therapeutics, Plenum Publishing, Radiation Research, Clinical Trials of Sequential, Drug Metab, Inhibition of Polyamine Metabolism, Trends Biochem New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 39
books:
See all 39 books this book cites
37
books
cite this book:
See all 37 books citing this book
- Mechanisms of Drug Resistance in Neoplastic Cells (Bristol-Myers Cancer Symposia) by Paul V. Woolley on 5 pages
- Cancer Chemotherapy: Challenges for the Future, Volume 10 by Kiyoji Kimura on 4 pages
- RADIATION RESEARCH 2 VOL SET by E. M. Fielden on page 99, page 345, and page 350
- Great Britain (Discovering Cultures) by Sharon Gordon in Front Matter
- Vitamin BSUB 6/SUB - Pyridoxal Phosphate (Coenzymes and Cofactors Series) by David Dolphin on page 74
See all 39 books this book cites
- Progress in Cell Cycle Research: Volume 2 by Laurent Meijer on page 176, page 177, and page 184
- Immune Interferon: Properties and Clinical Applications (Pharmacology and Toxicology: Basic and Clinical Aspects) by Roumen G. Tsanev in Front Matter
- Ryanodine Receptors: G Protein-Coupled Receptors (Handbooks in Pharmacology and Toxicology) by Vincenzo Sorrentino in Front Matter
- Therapeutic Modulation of Cytokines (Pharmacology and Toxicology) by M. W. Bodmer in Front Matter
- Drugs of Abuse and Addiction: Neurobehavioral Toxicology (Handbooks in Pharmacology and Toxicology) by Raymond Niesink in Front Matter
See all 37 books citing this book
Books on Related Topics
(learn more)
|
Tag this product(What's this?)Think of a tag as a keyword or label you consider is strongly related to this product.
Tags will help all customers organize and find favorite items. |
Sell a Digital Version of This Book in the Kindle Store
If you are a publisher or author and hold the digital rights to a book, you can sell a digital version of it in our Kindle Store.
Learn more
Customer Discussions
|
This product's forum
Active discussions in related forums
Search Customer Discussions
|
Related forums
|
