- Reduces acid levels to treat frequent heartburn
- Not intended for immediate relief; 14 day treatment cycle
- May take up to 4 days to reach full effect
- Not to be used by those allergic to omeprazole
- Please read all label information on delivery
Product Features
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In a recent study, we tested the strength of Prilosec OTC against frequent heartburn. Take a look at the results:
| 78% | of consumers were heartburn free on the first night | ||
| 81% | of consumers had complete relief*/only mild symptoms on day one | ||
| 94% | of consumers were satisfied with how well Prilosec OTC worked | ||
See for yourself if Prilosec OTC is right for you.
*It’s possible with Prilosec OTC. Use as directed for 14 days for treating frequent heartburn

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When you eat, millions of tiny pumps in your stomach produce acid to break down food — heartburn occurs when these excess acids reflux into your esophagus. Prilosec OTC works by directly blocking many of these pumps. Your stomach produces enough acid to digest food, but reduces excess acid — making it the most effective heartburn treatment choice and the #1 doctor recommended OTC acid reducer.† Prilosec OTC blocks heartburn for 24 hours with one pill a day.*
Antacids neutralize the acid in your stomach. Unlike the proactive PPI, antacids are commonly taken after you eat or when pain begins. While no heartburn treatments cure the condition, antacids provide only temporary relief.
H2 Blockers relieve heartburn symptoms by reducing the acid production. They begin working within an hour and last for 12 hours. H2 Blockers are not as effective in treating severe heartburn as PPIs.
* It’s possible with Prilosec OTC. Use as directed for 14 days for treating frequent heartburn.
†Wolters Kluwer (Acid reducer category).

Active ingredient (in each tablet)
Omeprazole magnesium delayed-release tablet 20.6 mg
(equivalent to 20 mg omeprazole)
Purpose
Acid reducer
Allergy alert: Do not use if you are allergic to omeprazole
Do not use if you have trouble or pain swallowing food, vomiting with blood, or bloody or black stools.
These may be signs of a serious condition. See your doctor.
Ask a doctor before use if you have
Ask a doctor or pharmacist before use if you are taking
Stop use and ask a doctor if
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
14-Day Course of Treatment
Repeated 14-Day Courses (if needed)
Inactive ingredients glyceryl monostearate, hydroxypropyl cellulose, hypromellose, iron oxide, magnesium stearate, methacrylic acid copolymer, microcrystalline cellulose, paraffin, polyethylene glycol 6000, polysorbate 80, polyvinylpyrrolidone, sodium stearyl fumarate, starch, sucrose, talc, titanium dioxide, triethyl citrate
Product Details
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Most Helpful Customer Reviews
4 of 4 people found the following review helpful:
5.0 out of 5 stars
A Lifesaver!,
By Scott Pointon "Former Marine, Librarian, Wood... (Crest Hill, IL United States) - See all my reviews (VINE VOICE) (REAL NAME)
This review is from: Prilosec OTC Acid Reducer, Delayed-Release Tablets, 28 Count (Health and Beauty)
As my acid reflux worsened over the years, I made the usual progression from antacid tablets, to Pepcid AC, and eventually to prescription medications like Prevacid and Nexium. Prevacid works great but it still requires a prescription and Nexium caused side effects in me. Once Prilosec was offered over the counter I gave it a try and was very impressed. After a week or two of taking it every day, I was able to decrease the dosage to the point where I only take it as needed now. Once I feel heartburn starting, or I eat something guaranteed to give me heartburn, I just take one of these and its gone in about 30 minutes...and when I say gone I mean gone for 10-12 hours.
I highly recommend this product to anyone who suffers acid reflux or chronic heartburn.
3 of 3 people found the following review helpful:
5.0 out of 5 stars
Great Product,
By
This review is from: Prilosec OTC Acid Reducer, Delayed-Release Tablets, 28 Count (Health and Beauty)
I suffered from heartburn everyday regardless of my diet. I now take 1 Prilosec a day and have no heartburn anymore!
2 of 2 people found the following review helpful:
3.0 out of 5 stars
Good product, but overpriced,
Amazon Verified Purchase(What's this?)
This review is from: Prilosec OTC Acid Reducer, Delayed-Release Tablets, 28 Count (Health and Beauty)
This medication works fine, but it is outrageously overpriced. Omeprazole is off patent, the materials cost is a tiny fraction of the cost of the packaging, and it is produced by reputable makers of generic drugs overseas, like India and Israel. Their product is sold in the US at a multiple of the price you can get if you find a way to order directly from the maker, such as PurpleOutlet.
Amazon used to sell omeprazole much cheaper, but no longer does. That product, in capsule form, was just as effective, but in much simpler packaging.
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