A Primer of Genome Science bridges the gap between standard genetics textbooks and highly specialized, technical, and advanced treatments of the subdisciplines. It provides an affordable and up-to-date introduction to the field that is suited to advanced undergraduate or early graduate courses. Bioinformatic principles and experimental strategies are explained side-by-side with the experimental methods, establishing a framework that allows teachers to explore topics and the literature at their own pace.
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Editorial Reviews
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"...remarkably comprehensive & organized given its length, covering most model organisms & many new & emerging techniques " -- Mark Lubkowitz, BioScience
--This text refers to an out of print or unavailable edition of this title.
About the Author
GREG GIBSON, North Carolina State University. - SPENCER MUSE, North Carolina State University.
--This text refers to an out of print or unavailable edition of this title.
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Most Helpful Customer Reviews
14 of 15 people found the following review helpful:
4.0 out of 5 stars
Excellent overview of Functional and Structural Genomics,
By A Customer
This review is from: A Primer of Genome Science (Paperback)
This somewhat understated book may be overlooked based on its title, and yet it represents the best book currently in print to provide a solid overview of the science and issues in genome science, functional and structural genomics, and the subdiscipline proteomics. Chapter 1 describes current progress with mapping genomes, including the human genome and other genomes in plants and animals. Chapter 2 describes sequencing approaches and gene identification. Chapter 3 deals with gene expression and technologies. Chapter 4 focuses on proteomics including brief introductions to 2D-PAGE and mass spectrometry. This chapter also briefly introduces the reader to structural genomics, or the prediction of protein structure based on sequence through threading and modeling. After a chapter on single nucletide polymorphisms and genotyping the book concludes with a chapter on integrating genome studies including the use of in silico approaches.Although scant in detail in parts, a major strength of the book is the wide coverage given to science of genomics and its offshoots. Overall an excellent course text for undergraduate or early postgraduate students or others interested in these emerging disciplines. I am not aware of any competing texts which such coverage and certainly not at the price of this one.
2 of 3 people found the following review helpful:
5.0 out of 5 stars
The future may view this text as a foundation for GS,
By RG (Durham, NC USA) - See all my reviews
This review is from: A Primer of Genome Science (Paperback)
Every technician and/or PI should own a copy of this text for their lab. With the logical diagrams and full explanation of the text, this book is really condensed and assumes some knowledge of molecular biology. This book does not assume knowledge of genomics, but rather serves as a manual.
5.0 out of 5 stars
good for beginner,
By JJ You "colorectal surgeon" (ChangHua, Taiwan) - See all my reviews
This review is from: A Primer of Genome Science, 2nd Edition (Paperback)
Except the computer-aided drug design, this book covers all the basic theory and useful information of bioinformatics. I recommended this book for anyone who needs to use the bioinformatics web, software tools. For the clinical physician, medical student, and molecular biology scientist, this book is very useful. Especially when you have no time to understanding the detail mathematic calculation, it quickly gives you a whole view and introduction.
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Inside This Book
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First Sentence:
All genome projects share a common set of aims, subsets of which are emphasized according to available resources, economic and scientific goals, and the biological attributes of the organism under study. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
most genome projects, hierarchical sequencing, higher eukaryotic genomes, recombination mapping, segregating sites, minimal genome, gene annotation, nucleotide diversity, cytological maps, tiling path, structural proteomics, genome scientists, disease loci, haplotype structure, protein microarrays, reporter dye, transcript abundance, metabolic control analysis, segmental duplications, gene ontology, gene content, shotgun sequencing, population stratification, linkage disequilibrium Key Phrases - Capitalized Phrases (CAPs): (learn more)
Genome Res, Natl Acad, Acids Res, Control Array, Male Array, New York, Sinauer Associates, United States, Drug Array, Discussion Questions, Online Mendelian Inheritance, Control Female, Control Male, Drug Female, Drug Male, International Human Genome Sequencing Consortium, Web Site Exercises The Web, Activated B-like, Celera Genomics, European Bioinformatics Institute, Genome Biology, Hrabe de Angelis New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
All genome projects share a common set of aims, subsets of which are emphasized according to available resources, economic and scientific goals, and the biological attributes of the organism under study. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
most genome projects, hierarchical sequencing, higher eukaryotic genomes, recombination mapping, segregating sites, minimal genome, gene annotation, nucleotide diversity, cytological maps, tiling path, structural proteomics, genome scientists, disease loci, haplotype structure, protein microarrays, reporter dye, transcript abundance, metabolic control analysis, segmental duplications, gene ontology, gene content, shotgun sequencing, population stratification, linkage disequilibrium Key Phrases - Capitalized Phrases (CAPs): (learn more)
Genome Res, Natl Acad, Acids Res, Control Array, Male Array, New York, Sinauer Associates, United States, Drug Array, Discussion Questions, Online Mendelian Inheritance, Control Female, Control Male, Drug Female, Drug Male, International Human Genome Sequencing Consortium, Web Site Exercises The Web, Activated B-like, Celera Genomics, European Bioinformatics Institute, Genome Biology, Hrabe de Angelis New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 14
books:
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8
books
cite this book:
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- Mendelian Inheritance in Man: Catalogs of Autosomal Dominant, Autosomal Recessive, and X-Linked Phenotypes by Dr. Victor A. McKusick MD on page 24, page 62, and page 63
- Fundamentals of Molecular Evolution by Dan Graur on page 130, and page 191
- Phylogenetic Trees Made Easy: A How-To Manual for Molecular Biologists by Barry G. Hall on page 130
- Atlas of Protein Sequence and Structure (Vol 5, Supplement 3) by Margaret O. Dayhoff on page 129
- The Practice of Statistics: TI-83/89 Graphing Calculator Enhanced by Dan Yates on page 130
See all 14 books this book cites
- Welcome to the Genome: A User's Guide to the Genetic Past, Present, and Future by Rob DeSalle in Back Matter
- Introduction to Computational Genomics: A Case Studies Approach by Nello Cristianini in Back Matter
- Forensic Science: An Introduction to Scientific and Investigative Techniques by Stuart James on page 249
- Neuroscience with CDROM by Dale Purves on page 28
- Essential Bioinformatics by Jin Xiong on page 260
See all 8 books citing this book
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