A Primer of Genome Science [Paperback]

Spencer V. Muse (Author), Greg Gibson (Author), Spencer Muse (Author)

Book Description

ISBN-10: 0878932348 | ISBN-13: 978-0878932344 | Publication Date: December 3, 2001 | Edition: 1st

This volume bridges the gap between standard genetics textbooks and highly specialised, technical, and advanced treatments of the subdisciplines. It provides an affordable and up-to-date introduction to the field that is suited to advanced undergraduate or early graduate courses. Bioinformatic principles and experimental strategies are explained side-by-side with the experimental methods, establishing a framework that allows teachers to explore topics and the literature at their own pace.

Editorial Reviews

Review

"...remarkably comprehensive & organized given its length, covering most model organisms & many new & emerging techniques " -- Mark Lubkowitz, BioScience

About the Author

GREG GIBSON, North Carolina State University. - SPENCER MUSE, North Carolina State University.

Product Details

• Paperback: 347 pages
• Publisher: Sinauer Associates; 1st edition (December 3, 2001)
• Language: English
• ISBN-10: 0878932348
• ISBN-13: 978-0878932344
• Product Dimensions: 9.3 x 6.9 x 0.7 inches
• Shipping Weight: 1.6 pounds
• Average Customer Review: 4.4 out of 5 stars  See all reviews (5 customer reviews)
• Amazon Best Sellers Rank: #2,116,915 in Books (See Top 100 in Books)

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Customer Reviews

Most Helpful Customer Reviews

14 of 15 people found the following review helpful:

4.0 out of 5 stars Excellent overview of Functional and Structural Genomics, March 19, 2002

By A Customer

This review is from: A Primer of Genome Science (Paperback)

This somewhat understated book may be overlooked based on its title, and yet it represents the best book currently in print to provide a solid overview of the science and issues in genome science, functional and structural genomics, and the subdiscipline proteomics. Chapter 1 describes current progress with mapping genomes, including the human genome and other genomes in plants and animals. Chapter 2 describes sequencing approaches and gene identification. Chapter 3 deals with gene expression and technologies. Chapter 4 focuses on proteomics including brief introductions to 2D-PAGE and mass spectrometry. This chapter also briefly introduces the reader to structural genomics, or the prediction of protein structure based on sequence through threading and modeling. After a chapter on single nucletide polymorphisms and genotyping the book concludes with a chapter on integrating genome studies including the use of in silico approaches.
Although scant in detail in parts, a major strength of the book is the wide coverage given to science of genomics and its offshoots. Overall an excellent course text for undergraduate or early postgraduate students or others interested in these emerging disciplines. I am not aware of any competing texts which such coverage and certainly not at the price of this one.

2 of 3 people found the following review helpful:

5.0 out of 5 stars The future may view this text as a foundation for GS, May 15, 2003

By 

RG (Durham, NC USA) - See all my reviews

This review is from: A Primer of Genome Science (Paperback)

Every technician and/or PI should own a copy of this text for their lab. With the logical diagrams and full explanation of the text, this book is really condensed and assumes some knowledge of molecular biology. This book does not assume knowledge of genomics, but rather serves as a manual.

5.0 out of 5 stars good for beginner, May 11, 2010

By 

JJ You "colorectal surgeon" (ChangHua, Taiwan) - See all my reviews

This review is from: A Primer of Genome Science, 2nd Edition (Paperback)

Except the computer-aided drug design, this book covers all the basic theory and useful information of bioinformatics. I recommended this book for anyone who needs to use the bioinformatics web, software tools. For the clinical physician, medical student, and molecular biology scientist, this book is very useful. Especially when you have no time to understanding the detail mathematic calculation, it quickly gives you a whole view and introduction.