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Principles and Applications of Asymmetric Synthesis Hardcover – February 7, 2001

ISBN-13: 978-0471400271 ISBN-10: 0471400270 Edition: 1st

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Editorial Reviews


"Lin and colleagues...consolidate and evaluate the most usefulmethodologies for producing enantiomerically pure or enrichedcompounds." (SciTech Book News, Vol. 25, No. 3, September2001)

"...a concise and fairly comprehensive overview..." (AngewandteChemie, 15 October 2001)

"...this book is worthy of purchase for library collections and forchemists who would like to have a one-volume summary of the last 20years of asymmetric synthesis. Those actively involved inasymmetric synthesis research will find this book most useful..."(Journal of Natural Products, Vol. 64, 2001)

"...a very good review of basic asymmetric methodology that can berecommended to students of organic chemistry..." (Journal ofMedicinal Chemistry, Vol. 44, No. 26 2001)

"a well balanced survey of stereocontrolled methodologies andsynthetic applications from which the reader can achieve valuableinformation." (ChemWeb, 14 January 2002)

"This book is quite readable and is highly recommended for thoseclinicians and administrators who want or need a practical andtime-effective way to approach assessment, treatment planning andoutcome measurement." (Keith Harris, Ph.D., clinical psychologistand supervisor of Victor Valley Behavioral Health Center, SanBernardino, California).

"There are many books on asymmetric synthesis, but this work...isone of the most useful and comprehensive" (Organic Process Research& Development)

From the Back Cover

Convenient reference covering one of the most important topics inchemical research today

Principles and Applications of Asymmetric Synthesis

Asymmetric synthesis remains a challenge to practicing scientistsas the need for enantiomerically pure or enriched compoundscontinues to increase. Over the last decade, a large amount ofliterature has been published in this field. Principles andApplications of Asymmetric Synthesis consolidates and evaluates themost useful methodologies into a one-volume resource for theconvenience of practicing scientists and students.

Authored by internationally renowned scientists in the field, thisreliable reference covers more than 450 reactions and includesimportant stoichiometric as well as catalytic asymmetric reactions.The first chapter reviews the basic principles, commonnomenclature, and analytical methods, and the remainder of the bookis organized according to reaction type. The text examines suchtopics as:
* Carbon-carbon bond formations involving carbonyls, enamines,imines, and enolates
* Asymmetric C-O bond formations including epoxidation,dihydroxylation, and aminohydroxylation
* Asymmetric synthesis using the Diels-Alder reaction and othercyclizations
* Applications to the total synthesis of natural products
* Use of enzymes in asymmetric synthesis

Practicing chemists in the pharmaceutical, fine chemical, andagricultural professions as well as graduate students will findthat Principles and Applications of Asymmetric Synthesis affordscomprehensive and current coverage.

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