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Principles of Biochemistry (4th Edition) 4th Edition

3.6 out of 5 stars 17 customer reviews
ISBN-13: 978-0131453067
ISBN-10: 0131453068
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Editorial Reviews

From the Publisher

A concise, introductory text that fills the gap between the standard encyclopedic volumes and the cursory overview texts. Widely praised in its previous edition for its accuracy, currency and clarity of exposition, the new edition has been thoroughly updated and revised to reflect recent changes in this dynamic discipline. --This text refers to an out of print or unavailable edition of this title.

From the Back Cover

This accurate and up-to-date book focuses on the basic principles of Biochemistry, with carefully selected examples of each. The areas of greatest change since the second edition are lipid metabolism, oxidative phosphorylation, and protein metabolism. Includes stereo views of many macromolecules; computer supplement; a section on molecular evolution; protein structures; molecular evolution; and developments in the area of gene expression, including the structure of RNA polymerase, the structure of the ribosome, genome organization, repair mechanisms, regulation of transcription and translation, and the structure and evolution of aminoacy1-tRNA synthetases. For readers interested in Biochemistry. --This text refers to an out of print or unavailable edition of this title.
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Product Details

  • Hardcover: 896 pages
  • Publisher: Prentice Hall; 4 edition (July 9, 2005)
  • Language: English
  • ISBN-10: 0131453068
  • ISBN-13: 978-0131453067
  • Product Dimensions: 8.8 x 1.3 x 11.2 inches
  • Shipping Weight: 4.4 pounds
  • Average Customer Review: 3.6 out of 5 stars  See all reviews (17 customer reviews)
  • Amazon Best Sellers Rank: #112,076 in Books (See Top 100 in Books)

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Customer Reviews

Top Customer Reviews

Format: Hardcover
Filled to the brim with useful, concise information, and helpful explanations. It also has very complete coverage of a broad variety of concepts and fields of study of biochemistry. While it can at times get bogged down in the details, it was extremely helpful to me during my biochemistry class, and inspired in me a desire to continue educating myself in the field. I am keeping this book rather than selling it, because I'm certain it will be of great use to me in my further studies in biology and medicine.
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Format: Hardcover
This book was adopted by my university for a senior level / first year graduate level biochemistry course. It is well written and contains no messy jargon. Literally all of the text is useful information. In addition, it is concise.

My chief complaints about the book are: 1) the illustrations require substantial updating to be compared to what is presently available even in inferior texts. 2) it lacks clinical/biological correlations and focuses instead on the quantitative nature of biochemistry (acid base calculations etc) Clinical correlations are certainly essential to applying biochemistry concepts. If this book had either or both of these two items, it would have earned 5 stars from me!

Instead, I recommend the following texts:

- Biochemistry: outstanding illustrations and concept coverage.

- Marks' Basic Medical Biochemistry: A Clinical Approach: outstanding clinical correlations with concise concept coverage and good illustrations (although not in full color)

- Lehninger Principles of Biochemistry, Fourth Edition: outstanding text and illustrations!
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Format: Hardcover
This is one of the most readable texts for biochemistry on the market. It would be most useful for undergraduates and medical students. It is almost useless for graduate students in the biological sciences because it doesn't talk enough about experimental strategies. The older version of this text was much cooler because it has stereoviews. This feature makes the book stand out because the stereoviews are awesome. Whose idea was it to remove them??? This would make a good first book in biochemistry, but for upper level students I would recommend Stryer.
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Format: Hardcover
I am a biochemistry professor. After years of using another text I decided to try the Voet & Voet text. I was very excited about their latest edition and couldn't wait to teach with it. Unfortunately it was a disaster. There are far too many trees in Voet & Voet, and students couldn't see the forest this year. For next year I am looking at "Principles of Biochemistry" 4th edition by Horton et al.

So, in response to V. Kankanala below, student perspectives in these Amazon Reviews are very useful to those of us assigning the texts.
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Format: Hardcover Verified Purchase
4/5 stars for the simplicity and organization of this textbook.It definitely goes into detail where needed and isn't hard to comprehend.

I used this textbook for a 300 level biochem1 course & it was very useful.
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Format: Hardcover Verified Purchase
My class uses the 5th edition of this book, but we were told by the professor that the 4th edition and the international edition are the exact same text, just different page numbers. This edition is considerably cheaper than the 5th, so I chose it. This is a very well written textbook. It is super easy to follow, and definitely not too dense.

I have seen the 5th edition, and it's definitely an improvement. The "key" words are colored in red so they are easier to find, compared to this (4th) edition where they are either bolded or italicized which makes looking for that quick definition a bit of a pain. The 5th edition also has a few more figures/pictures that this book doesn't have, and the layout is a tad different, but still all the same info is there.
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Format: Hardcover Verified Purchase
but I guess that happens when returning to complete ones higher education after 3 decades. The info IS understandable....the me to say that about ANY biochemistry resource is high praise.
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Format: Hardcover Verified Purchase
I had to purchase the book because of the General Biochemistry course that I took at school. Although it is a well-written book, it does not provide the materials that are covered in our class. I do not even know why this book is required for an upper-division general biochemistry course! In other words, the book is very superficial and does not have enough substance.

Moreover, there are a lot of errors in the answer key section. You can pay slightly more and buy Lehninger Principles of Biochemistry, but at least you would have something that you can learn from. I would not recommend this book.
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