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St. John's Wort and its Active Principles in Depression and Anxiety (Milestones in Drug Therapy) [Hardcover]

Walter E. M�ller (Author)

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Book Description

Publication Date: April 6, 2005 | Series: Milestones in Drug Therapy

Hypericum extract preparations are used extensively in many countries to treat mildly to moderately depressed patients. While this was based previously on traditional experience, extensive research over the last 10 years has given a broad preclinical and clinical basis to justify the use of Hypericum as an antidepressant. This book reviews the available data related to the biochemical, functional, and behavioural pharmacology of Hypericum and its active constituents. The clinical chapters overview the evidenced basis for its use as an antidepressant, initial data in anxiety and somatoform disorders, and the site effect profile of Hypericum and its possible relevant drug interactions. The known pharmacokinetics of the relevant constituents and the biopharmaceutical quality of commercially available Hypericum preparations are also discussed.

#outer_postBodyPS { display: none; } #psGradient { display: none; } #psPlaceHolder { display: none; } #psExpand { display: none; } Hypericum extract preparations are used extensively in many countries to treat mildly to moderately depressed patients. While this was based previously on traditional experience, extensive research over the last 10 years has given a broad preclinical and clinical basis to justify the use of Hypericum as an antidepressant. This book reviews the available data related to the biochemical, functional, and behavioural pharmacology of Hypericum and its active constituents. The clinical chapters overview the evidenced basis for its use as an antidepressant, initial data in anxiety and somatoform disorders, and the site effect profile of Hypericum and its possible relevant drug interactions. The known pharmacokinetics of the relevant constituents and the biopharmaceutical quality of commercially available Hypericum preparations are also discussed.

Editorial Reviews

Review

Dieses Buch kann sicherlich als eines der aktuellsten Zusammenstellungen wissenschaftlicher Daten zu unterschiedlichen Aspekten von Johanniskraut-Extrakten und deren wichtigsten Inhaltsstoffe angesehen werden. (Pharmazie in unserer Zeit)

Product Details

Hardcover: 196 pages
Publisher: Birkh�user Basel; 1 edition (April 6, 2005)
Language: English
ISBN-10: 3764361603
ISBN-13: 978-3764361600
Product Dimensions: 9.5 x 6.8 x 0.6 inches
Shipping Weight: 1.4 pounds
Amazon Best Sellers Rank: #5,173,593 in Books (See Top 100 in Books)

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Inside This Book (learn more)

First Sentence:
St. John's Wort (Hypericum perforatum) is a member of the Hypericaceae family. Read the first page

Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
pure rutin, biorelevant media, hyperforin content, perforatum extracts, sodium conductive pathways, major antidepressant constituent, hypericum extract, possible antidepressant component, synthetic antidepressants, total hypericin, antidepressant activity, inhibiting constituent, synaptosomal uptake, forced swimming test, immobility time, herbal medicinal products, hypericin content, escape deficit, escape test, vesicular uptake, unavoidable stress, appetitive behaviour, behavioral despair, dissolution testing, extract doses

Key Phrases - Capitalized Phrases (CAPs): (learn more)
John's Wort, Planta Med, Clin Pharmacol, Life Sci, Geriatr Psychiatry Neurol, Pharmacol Biochem Behav, Birkhauser Verlag, Pharm Pharmacol, Pharmacol Exp Ther, Alcohol Alcohol, Biol Psychiatry, Pharmacol Res, Anal Chem, Nat Prod, Antivir Res, Biochem Pharmacol, New York, World Health Organization, Behav Pharmacol, Dokladv Akadernii Nauk Sssr, Dtsch Apoth Ztg, Exp Biol, Hamilton Depression Scale, Neurosci Lett, Phvtochem Anal

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Citations (learn more)

This book cites 1 book:

Cognitive Enhancing Drugs (Milestones in Drug Therapy) by Jerry J. Buccafusco in Back Matter

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