Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 2e [Paperback]

David E. Golan (Editor), Armen H. Tashjian (Editor), Ehrin J. Armstrong (Editor), April W. Armstrong (Editor)

Book Description

Publication Date: April 27, 2007 | ISBN-10: 0781783550 | ISBN-13: 978-0781783552 | Edition: 2.00

This primary textbook for a first course in pharmacology offers an integrated, systems-based, and mechanism-based approach to understanding drug therapy. Each chapter focuses on a target organ system, begins with a clinical case, and incorporates cell biology, biochemistry, physiology, and pathophysiology to explain how and why different drug classes are effective for diseases in that organ system.

Over 400 two-color illustrations show molecular, cellular, biochemical, and pathophysiologic processes underlying diseases and depict targets of drug therapy. Each Second Edition chapter includes a drug summary table presenting mechanism, clinical applications, adverse effects, contraindications, and therapeutic considerations. New chapters explain how drugs produce adverse effects and describe the life cycle of drug development.

The fully searchable online text and an image bank are available on thePoint.

Editorial Reviews

Review

Doody's Review, Thomas L Pazdernik, PhD(University of Kansas Medical Center) -- This is a basic pharmacology textbook with an emphasis on the biochemical and cellular mechanisms required for understanding the treatment of pathophysiological conditions. This is a collaborative effort by Harvard medical faculty and students to prepare a book useful for students who are studying pharmacology as part of their curriculum. This is particularly useful for courses that focus on the biochemical, cellular, and physiological basis of drug action. The strength of this book lies in the numerous excellent figures that explain the cellular and molecular aspects of drug actions on a physiological basis. This second edition has 100 new or extensively redesigned figures. The sections on fundamentals of drug development and regulation and frontiers in pharmacology provide a perspective not found in most fundamental pharmacology books. An access code is provided for an electronic version of the book and images. A companion case-based workbook, Principles of Pharmacology Workbook, by Farrell (Lippincott Williams Wilkins, 2008), reviews important concepts and drug classes in a question-and-answer format that is valuable for course and board exam review. Four Stars. Weighted Numerical Score: 93

Product Details

• Paperback: 985 pages
• Publisher: Lippincott Williams & Wilkins; 2.00 edition (April 27, 2007)
• Language: English
• ISBN-10: 0781783550
• ISBN-13: 978-0781783552
• Product Dimensions: 10.7 x 8.4 x 1.2 inches
• Shipping Weight: 3.9 pounds
• Average Customer Review: 4.2 out of 5 stars  See all reviews (10 customer reviews)
• Amazon Best Sellers Rank: #90,470 in Books (See Top 100 in Books)
  • #26 in Books > Medical Books > Dentistry > Dental Assisting

Customer Reviews

Most Helpful Customer Reviews

13 of 13 people found the following review helpful:

5.0 out of 5 stars Just get this book as soon as possible!, August 29, 2007

By 

Roberto Yunes (Mendoza, Argentina) - See all my reviews
(REAL NAME)   

This review is from: Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 2e (Paperback)

The second edition is usually better than the first one, and the first one was simply excellent! A great book, with a problem-based learning approach in mind, updated and with many new and important chapters (Protein Therapies, Drug Delivery Advances, Pharmacogenetics, among others). The good thing with this book is that any chapter deals with the necessary coverage of anatomy, physiology, pathology and so on before coming to the drugs facts. With the early med student in mind, the book will be useful for any health related career. The book is clear, is concise -notwithstanding comprehensive-, and with a complete set of drug facts tables at the end of most chapters. Simply said, the kind of book I'd liked to write myself.

One more thing: The book is brilliantly complemented by its companion book, "Principles of Pharmacology Workbook", by S. Farrell, a great account of more than 100 clinical cases regarding each chapter of the main book, with no less than five questions -and their corresponding answers- for every one of the cases. The ideal complement to make this couple of books the best pharmacology books in the scene today. I work very actively with both of them in teaching my own pharmacology courses.

6 of 6 people found the following review helpful:

4.0 out of 5 stars Good Supplimental Pharmacology Text, January 28, 2010

By 

Project Sleep Deprivation (Oregon, USA) - See all my reviews

Amazon Verified Purchase

This review is from: Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 2e (Paperback)

This book can help you get a handle on important concepts in modern pharmacology. The organization is sensible and the writing/editing is above average. I must admit that Goodman & Gilman's (G&G) "The Pharmacological Basis of THERAPEUTICS" is a more comprehensive book that I plan on keeping for a long time. However, G&G can be difficult to read if you have not seen its material previously. Thus I think that this book is a highly appropriate learning tool. So if you are a professional Pharm.D. student, this book can/will help you, but you will need to master the content to a more detailed degree to succeed (get G&G 11th+ ed). That being said, this book will still benefit you greatly. Also, if you are a student or curious person whom wants to know how drugs work, this book should cover all your basic needs.

This book should be all that a M.D. or R.N. student should need (specialist excluded) to make it through their training. Absolute genius students can get by without this book, but they will still have to read something. The book is quit clinically oriented and covers most of the first-line therapeutics with examples. It does not provide much medicinal chemistry (not this books job anyway). The end of chapter drug summaries are helpful. One of my personal favorite properties of the book is that it errs on the side of redundancy, if two concepts are intimately connected in different chapters, without being verbose (like me). This book does not cover pharmacokinetics past what is clinically relevant (no math to speak of), unless the kinetics of the drug are highly important in predicting its pharmacodynamics. I have not used the book's online resources. The one thing I must restate is this: this book is not an exhaustive authority on all things pharmacological, but is a helpful learning tool to get up to speed for clinical practice in typical situations. I consistently use this book as a helpful tool as a Ph.D. candidate pursuing a dual specialization in pharmacology and toxicology. I purchased the book through Amazon.

4 of 4 people found the following review helpful:

5.0 out of 5 stars Excellent textbook for Medical Pharmacology, September 23, 2008

By 

EBZ "EBZ" (Medical College) - See all my reviews

This review is from: Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 2e (Paperback)

Written by a medical student
Comparing this to Lange Pharmacology(Big and Little version), Golan's Pharmacology is a brilliantly written text, well organized, and developed for the Medical student in mind. Its very easy to read with language thats appropriate for the student. All drugs are logically laid out in a organized manner per chapter. Chapters build up a step wise manner: normal physiology section, the pathophysiology or pathology of disease section, finally the pharmacology section. Not a random collection of facts or details like Lange series, that book is extremely difficult to follow. I feel the authors of Lange pharmacology omit a lot of important details, like not writing much about medications' side effects, making it difficult to distinguish between various medications of each group from each other. Golan's Pharmacology thankfully was written to explain the various differences in each drug mechanics, therapeutics, and side effects. Best of all, the the last chapter in each unit has an integrated pharmacology section teaching competently how to utilize combination therapy. Should be the standard text in medical pharmacology courses!