Problem-Based Immunology (Paperback)

by Reginald M. Gorczynski (Author), Jacqueline Stanley (Author)

Editorial Reviews

Product Description
It's one thing to understand the basic science of immunology. It's another thing to know how that science applies to the realities of patient care. This new resource uses skillfully presented clinical case studies to efficiently demonstrate the practical relevance of immunology knowledge in diagnosing a wide range of challenging conditions. It offers as an ideal way to review the fundamental principles of immunology ... and see them translated into real-world diagnosis and management!

• Covers each major area of the field - immunization, hypersensitivity, autoimmunity, immunodeficiency disorders, tumor immunology, and transplantation.
• Provides a concise overview of the basic concepts in each area, followed by 6-10 succinct and well-organized case studies that illustrate the associated clinical applications.
• Begins each case study with an initial case presentation, complete with full-color clinical photographs, allowing you to put your diagnostic reasoning skills to the test - followed by a list of the key clinical features involved in the case · a one-paragraph discussion of each differential diagnostic possibility · and a summary of the correct diagnosis and treatment approach

About the Author
Reginald M. Gorczynski, MD, Professor, Department of Surgery and Immunology, University of Toronto Faculty of Medicine, Toronto, Ontario; and Jacqueline Stanley, PhD, Professor, Department of Cell and Molecular Biology, Course Director, Immunology, St. George's University School of Medicine, St. George's, Grenada, West Indies

Product Details

• Paperback: 268 pages
• Publisher: Saunders; 1 edition (February 17, 2006)
• Language: English
• ISBN-10: 1416024166
• ISBN-13: 978-1416024163
• Product Dimensions: 9.9 x 7.9 x 0.5 inches
• Shipping Weight: 1 pounds (View shipping rates and policies)
• Average Customer Review: 5.0 out of 5 stars See all reviews (3 customer reviews)
• Amazon.com Sales Rank: #325,449 in Books (See Bestsellers in Books)

Customer Reviews

Most Helpful Customer Reviews

2 of 2 people found the following review helpful:

5.0 out of 5 stars Must have for Clinical Immunology.., August 10, 2008

By	Francis S. Dossou (MI,USA) - See all my reviews (REAL NAME)

This book is a wonderful tool for Medical Immunology. My second year course at medical school runs only two weeks and there are so many informations and so many concepts to digest. At the beginning I was very skeptical about buying the book because its a very new book( first and only edition, from 2006) and there is no written review as I am the first person to writte this review on Amazon. It first start by discussing every necessary information to understand each concept then it move over to talk about clinical cases related to each concept. It also go to the very bottom of each condition and speculate concisely on the informations necessary we need to understand. For exemple ADA deficiency is a subtype of the wide range of SCIDs and in our notes there are no much infos about ADA and you really need to go back to the biochem notes to clearly understand the mechanism of ADA which will be very hard to do w/in two weeks. And the authors clearly break down the facts about ADA by stating on page 10 w/in a very short paragraph that "..ADA is required for purines metabolism and which is more active in lymphocytes, particularly T lymphocytes. In the absence of this enzyme, toxic metabolites accumulate and inhibit DNA synthesis so proliferation does not occur in response to polyclonal activators". They first save me a trip to last year biochem notes which are accross my table on the living room then, they break down why exactly ADA deficiency inhibit polyclonal activation. Great book I would recommend to any medical student for the Immuno class.

1 of 1 people found the following review helpful:

5.0 out of 5 stars Great learning for all levels in immunology - from novice to advanced!, October 9, 2008

By	Dr. Dan (Miami, FL) - See all my reviews

As an allergy/immunology fellow trying to digest all the information in Abbas and Janeway as it pertains to my patients clinically, I needed a source that helped my brain put it all together. I first noticed this book in my university bookstore and, my burgeoning collection of books be damned, decided to give it a look. I very quickly realized this would be an instrumental book in my learning about clinical issues in immunology, particularly the immunodeficiencies. From the big hitters like SCID to the minutia of innate immunity like TLR4 deficiency - it's all there - and presented in a concise, interesting case-based approach, with beautiful multi-color photographs and diagrams. After looking the book over, other fellows in my program have also purchased this book. I use this book regularly when I want to better understand and synthesize the material I am reading in my Abbas textbook.

My complaints with this book are minor. For one, as the previous reviewer said, it's a first-and-only 2006 edition so far. (Not a problem just yet, though.) Second, each case presentation is followed up with "Group Discussion" questions, which are supposed to stimulate thoughts about the case. The problem is, these questions many times give away the etiology of the case, which ruins the suspense! Finally, the pages themselves are slightly thin, so heavy highlighting (guilty as charged) will tend to bleed through the pages a little, but not much. Again, these are all very minor complaints.

Other than that, I highly, highly recommend this book. If you are a med student, resident, fellow, or even attending seeking a great case-based approach to better learning/solidifying your clinical knowledge of immunology, this is your book. I love it.

5.0 out of 5 stars Great book, Very well organized , January 11, 2009

By	Mr. Vadim Khachaturov "spider" (New York, NY USA) - See all my reviews (REAL NAME)

The book is organized into sections such as autoimmunity and immunization and within those sections there are clinical cases. Each clinical case is dealt with in detail. Clinical cases make the book more medically oriented and help retain the information. There are multiple choice problems at the end of the book for each section.