Protecting Groups (Thieme Foundations of Organic Chemistry Series) [Hardcover]

Philip J. Kocienski (Author)

Book Description

Publication Date: December 1994 | ISBN-10: 0865775583 | ISBN-13: 978-0865775589

The didactic presentation of the material makes this book an essential bench-top tool not only for specialists in organic chemistry, but also for students and all those involved in the preparation of organic molecules. Key Features:

- a critical survey of the most used protecting groups, as used by organic chemists

- organization based on functional groups: hydroxyl ; diol; carbonyl; carboxyl; amine

- special emphasis placed on deprotection conditions applied to complex structures where selectivity is a prime issue

- transformations accompanied by key experimental details

- examples from the recent literature span a wide domain of organic synthesis

- over 500 schemes aid visual retrieval - end-of-chapter list reviews which amplify topics covered.

--This text refers to an out of print or unavailable edition of this title.

Editorial Reviews

Review

"Possesses a number of noteworthy features: it is well organized, covers useful information, and is eminently readable--an excellent combination. A chart of protection methods and functional groups is located inside the front cover and provides almost immediate access to any transformation that is of interest. Additionally, the index is very thorough and provides access in a more traditional manner. The coverage of the text is extensive and includes references from 1990 to 2001. There are several other distinctive features that make this volume noteworthy: for example, at several junctures, the characteristic features of the H-! And C-13 NMR spectra of the protecting group are noted. This makes practical information immediately at hand so the reader does not have to access the original literature to obtain this information. Also, the key functional groups undergoing the reaction are highlighted in blue in the drawings. Finally, the price is right, well within the means of students and faculty alike. Although the book is paperback, the price is very reasonable considering that this is the sort of book that will remain in your library for many years to come and will take its place alongside the other indispensable volumes used daily in research. At the moment, this volume looks bright and new sitting on my bookshelf, but I anticipate that it will quickly take on the well-worn patina of a book that sees extensive use by everyone in my lab."--Journal of the American Chemical Society

--This text refers to the Paperback edition.

Product Details

• Hardcover: 260 pages
• Publisher: Thieme Medical Pub (December 1994)
• Language: English
• ISBN-10: 0865775583
• ISBN-13: 978-0865775589
• Product Dimensions: 9.8 x 7 x 0.8 inches
• Shipping Weight: 1.4 pounds
• Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
• Amazon Best Sellers Rank: #10,088,439 in Books (See Top 100 in Books)

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Customer Reviews

Most Helpful Customer Reviews

1 of 1 people found the following review helpful:

5.0 out of 5 stars Extraordinary Useful, April 8, 2010

By 

Nataliya Chumachenko (Boulder, CO) - See all my reviews
(REAL NAME)   

This review is from: Protecting Groups (softcover) (Paperback)

This book reveals the logic behind the described methods and discuss the mechanisms. I never expected I would want to own another protection/deprotection reference book in addition to Greene's "Protective groups in organic synthesis" and I was wrong. Kocienski managed to present broad, comprehensive overview of a "boring but necessary" information as a most enjoyable and thought-provoking reading. The book is filled with carefully selected pieces from total syntheses, often illustrating formidable problems solved in a beautiful way. The book does not reference every single known methods as Greene's does, but is extraordinary informative. I believe the intellectual values of both books are comparable. If you are facing a problem (as usual :) or are designing a complex synthesis, I would suggest to read Kocienski's book first and then supplement it from Greene's. Works for me. If you enjoy the Synthesis, you will love this book.
Nataliya, PhD in Organic Synthesis.