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G  Protein-Coupled Receptors (Methods in Signal Transduction Series)
 
 
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G Protein-Coupled Receptors (Methods in Signal Transduction Series) [Hardcover]

Gabriel Berstein (Editor)
5.0 out of 5 stars  See all reviews (1 customer review)

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Book Description

0849333849 978-0849333842 September 24, 1999 1
Covering recently developed methods in membrane-bound receptors, this book emphasizes receptor structure and function, knowledge of which is essential to the study of signal transduction.
G Protein-Coupled Receptors has culled contributors from domestic and international sources, providing a broad base of knowledge. Some topics covered are the regulation of receptors; phosphorylation of G-protein-coupled receptors and ion channel receptors; desensitization studies using electrophysiological or confocal microscopic methods and the search for endogenous ligands for orphan receptors.
This volume is useful at both the university and industrial levels, and is of particular interest to those who are developing therapeutic approaches to diseases using drugs that influence receptor activation.

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Product Details

  • Hardcover: 424 pages
  • Publisher: CRC Press; 1 edition (September 24, 1999)
  • Language: English
  • ISBN-10: 0849333849
  • ISBN-13: 978-0849333842
  • Product Dimensions: 9.6 x 6.5 x 1.2 inches
  • Shipping Weight: 1.6 pounds (View shipping rates and policies)
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #2,748,879 in Books (See Top 100 in Books)

 

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1 of 1 people found the following review helpful:
5.0 out of 5 stars Comprehensive membrane receptor methodology compendium, December 2, 2001
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This review is from: G Protein-Coupled Receptors (Methods in Signal Transduction Series) (Hardcover)
Comprehensive compendium from leading scientists in the field of membrane receptor function and methodology. Appealing material is presented by Dr. Birdsall on receptor-radioligand binding analysis and ligand-receptor allosteric interactions. Other highlights are the chapters covering heterologous receptor expression techniques, receptor-ion channel methodology and receptor-structure analysis. A must have for those interested in this field.
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Inside This Book (learn more)
First Sentence:
Radioligand binding studies are relatively easy to perform, often very accurate, and can usually be interpreted according to a mechanistic model to yield fundamental chemical quantities, such as the affinity of a ligand for a receptor or the number of receptors in a tissue. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
rat atrial cells, affinity ratio plot, zeocin vectors, appropriate holding potential, bicontinuous lipidic cubic phases, expression casette, radioligand depletion, lipidic mesophases, screening orphan receptors, pastoris clones, solution changer, using melanophores, rat neurotensin receptor, allosteric agent, cultured melanophores, bound dpm, combinatorial diffusion assay, melanophore cells, protein coupling selectivity, radioligand concentration, protein contact sites, receptor under study, free radioligand, ternary complex model, internalization assay
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Cell Biol, Cold Spring Harbor, Experimental Procedure, Trends Pharmacol, Boehringer Mannheim, Life Technologies, Linearizing Transformation of the Data, Peptide Protein Res, Oxford University Press, Practical Approach, Adsorption of Ligands, Functionally Critical Residues, Inhibition of Receptor Internalization, Life Sciences, Molecular Devices, New England Nuclear, Pigment Cell Res, Receptor-Ligand Interactions, Receptors Channels, Trends Biotechnol, X-Ray Crystallography of Membrane Proteins, Ann Arbor, Axon Instruments Inc, Humana Press
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