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Protein Crystallization (Iul Biotechnology Series) 1st Edition

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ISBN-13: 978-0963681751
ISBN-10: 0963681753
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--This text refers to an alternate Hardcover edition.

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Editorial Reviews


"This is an essential handbook for anyone engaged in crystallization of macromolecules. It is exceptionally well organized and illustrated and has contributions from all the leaders in what continues to be a challenging and critically important field." --Dr. William L. Duax, American Crystallographic Association, Executive Officer

"Why is crystallization important? At different times, different aspects of protein crystallography have assumed the role of bottleneck. Thus at one time the bottleneck consisted of the lack of a methodology for structure determination, even if a sufficient number of diffraction intensitities were available for structure solution. With the advent of powerful methods for structure solution, the bottleneck shifted to the difficulty in obtaining crystals in sufficient number and of suitable quality to do the diffraction experiment. The present book is dedicated to the problem of describing current methods for protein crystallization and describing them as clear laboratory protocols." --Dr. Herbert A. Hauptman, 1985 Nobel Laureate in Chemistry

"I used the first edition as a graduate student. It was a perfect guide for protein crystallizers at all stages of their careers, providing methodical, clear explanations in lay terminology." --Dr. Lata Govada, Imperial College London --This text refers to an alternate Hardcover edition.

From the Back Cover

Completely revised and updated, Protein Crystallization, 2nd Edition is a greatly expanded follow-up to the best-selling 1st edition. No previous background in crystallization is assumed. Contents include:

--Completely new chapters on high-throughput methods, mass spectrometry, microcalorimetry, counterdiffusion, heavy-atom derivatization, selenomethionine-labeling, rational strategies for crystallization, and protein modification to improve crystallization.
--Updated chapters on formulation of the protein before crystallization, characterization of the protein by dynamic light scattering, classic methods and the phase diagram, seeding, and cryoprotection of the crystals.
--Thirty full-color plates for evaluating crystallization drops.
--Separate section of laboratory exercises, ideal for crystallization courses.
--A-Z glossary. --This text refers to an alternate Hardcover edition.

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Product Details

  • Series: Iul Biotechnology Series
  • Hardcover: 306 pages
  • Publisher: Intl Univ Line; 1 edition (February 1, 1999)
  • Language: English
  • ISBN-10: 0963681753
  • ISBN-13: 978-0963681751
  • Product Dimensions: 1.2 x 6.5 x 9.8 inches
  • Shipping Weight: 1.4 pounds
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #3,276,998 in Books (See Top 100 in Books)

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The book has been very useful for different level students because is very practice and undestable.
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