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Protein NMR for the Millennium (Biological Magnetic Resonance)
 
 
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Protein NMR for the Millennium (Biological Magnetic Resonance) [Hardcover]

N. Rama Krishna (Editor), Lawrence J. Berliner (Editor)

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Book Description

January 31, 2003 0306474484 978-0306474484 1
Protein NMR for the Millennium is the third volume in a special thematic series devoted to the latest developments in protein NMR under the Biological Magnetic Resonance umbrella. This book is divided into three major sections dealing with significant recent advances in the study of large proteins in solution and solid state, structure refinement, and screening of bioactive ligands.
Key Features:
  • TROSY,
  • Segmental isotope labeling of proteins,
  • Hydrogen bond scalar couplings,
  • Structure refinement based on residual dipolar couplings,
  • Written by the world's foremost experts who have provided broad leadership in advancing the protein NMR field.

Editorial Reviews

Review

`The book is generally easy to read for those with an appreciable knowledge of protein NMR spectroscopy. [...]presents a timely review of many recently developed techniques for the study of large proteins by NMR spectroscopy. We highly recommend it as a reference for anyone with an active interest in this field.'
Journal of the American Chemical Society, 125:51 (2003)

About the Author

Dr. N. Rama Krishna is Professor of Biochemistry and Molecular Genetics and the Director of the NMR Core Facility at the University of Alabama at Birmingham. He has previously served as Guest Editor for Volumes 16 (Modern Techniques in Protein NMR, 1998) and Volume 17 (Structure Computation and Dynamics in Protein NMR, 1999). Dr. Lawrence J. Berliner is currently Professor and Chair of the Department of Chemistry and Biochemistry at the University of Denver after retiring from Ohio State University, where he spent a 32-year career in the area of biological magnetic resonance (EPR and NMR). He is the Series Editor for Biological Magnetic Resonance, which he launched in 1979.

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Inside This Book (learn more)
First Sentence:
The non-equivalence of certain magnetization transfer pathways in NMR experiments viewed from the stand point of the decay of evolving coherences known as nuclear spin relaxation was recognized at the very onset of the multidimensional multinuclear NMR (Griffey and Redfield, 1987; Gueron et al., 1983; Rance, 1988; Shimizy, 1964). Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
dual domain construct, rotational diffusion axes, overall rotational diffusion tensor, ubiquitin encapsulated, dipolar restraints, experimental dipolar couplings, backbone dipolar couplings, segmental labeling, alignment tensor, different alignment media, dipolar coupling information, segmental isotopic labeling, measured dipolar couplings, pseudo contact shifts, global fold determination, using dipolar couplings, residual dipolar couplings, molecular coordinate frame, rotational resonance conditions, deuterated proteins, pseudocontact shifts, magnetization transfer pathways, encapsulated proteins, angle restraints, bond scalar couplings
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Del Bene, Kluwer Academic Publishers, American Chemical Society, Acad Sci, Academic Press, Nature Struct, Chem Phys, Nucleic Acids Res, Protein Science, Acta Cryst, Chemischen Industrie, York Avenue
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