A comprehensive introduction to the art and science used by the biochemist and process engineer in the design and optimization of large-scale protein-purification processes. Covers the basics of proteins' properties, the unit operations involved in protein purification as well as important related issues of process design, integration with upstream operations, cost and timing to market. Includes an abundance of figures and tables.
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Most Helpful Customer Reviews
5 of 5 people found the following review helpful:
5.0 out of 5 stars
An excellent text,
By Bill F. (San Diego, CA USA) - See all my reviews
This review is from: Protein Purification: Design and Scale up of Downstream Processing (Hardcover)
Scott Wheelwright does an excellent job of bringing together all the diverse problem areas that impact today's downstream processing. This book is one of the "must have's" of the field, and was obviously written with much attention to the myriad of details that are involved in protein purification process development.
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Inside This Book
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First Sentence:
The design of a process for the large-scale purification of a protein is one of several complex activities that must be successfully completed to bring a product to market. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
species heuristics, grinding media, ion exchange matrix, ultimate scale, hydrophobic matrix, relative centrifugal force, bead mill, transmembrane pressure, protein purification, linear flow rate, hydrophobic interaction chromatography, equilibration buffer, ion exchange step, concentration polarization, preparative chromatography, lyotropic series, basic side chains, gel filtration chromatography, design heuristics, peripheral velocity, reversed micelles, ligand density, depth filters Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, John Wiley, Journal of Chromatography, Analytical Biochemistry, Marcel Dekker, Academic Press, High Resolution Methods, Springer Verlag, American Chemical Society, Biochemical Engineering, Recent Developments, San Francisco, Step Volume, Van Deemter, Courtesy of Pharmacia, Practical Approach, Process Biochemistry New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
The design of a process for the large-scale purification of a protein is one of several complex activities that must be successfully completed to bring a product to market. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
species heuristics, grinding media, ion exchange matrix, ultimate scale, hydrophobic matrix, relative centrifugal force, bead mill, transmembrane pressure, protein purification, linear flow rate, hydrophobic interaction chromatography, equilibration buffer, ion exchange step, concentration polarization, preparative chromatography, lyotropic series, basic side chains, gel filtration chromatography, design heuristics, peripheral velocity, reversed micelles, ligand density, depth filters Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, John Wiley, Journal of Chromatography, Analytical Biochemistry, Marcel Dekker, Academic Press, High Resolution Methods, Springer Verlag, American Chemical Society, Biochemical Engineering, Recent Developments, San Francisco, Step Volume, Van Deemter, Courtesy of Pharmacia, Practical Approach, Process Biochemistry New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 40
books:
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- Protein Purification (DISCONTINUED (UCLA Symposium on Molecular and Cellular Biology)) by Burgess on 6 pages
- Protein Purification: Principles and Practice by Robert K. Scopes on page 39, page 51, and page 97
- Recent Developments in Chemical Process and Plant Design by Y. A. Liu on page 23, page 24, and page 25
- Centrifugation: A Practical Approach by D. Rickwood on page 50, page 71, and page 84
- Protein Purification: Principles, High-Resolution Methods, and Applications by Jan-Christer Janson on page 51, page 170, and page 193
See all 40 books this book cites
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